UT Southwestern Center for Translational Medicine

德州大学西南转化医学中心

• 批准号: 10412142
• 负责人: Keith Edward Argenbright
• 金额: $ 130.57万
• 依托单位: UT SOUTHWESTERN MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-05-26 至 2026-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10412142
• 关键词: Academy; Acceleration; Address; Applications Grants; Award; Awareness; Basic Science; Career Choice; Clinical Research; Collaborations; Communities; Community Health; Competence; Cost Sharing; Custom; Development; Discipline; Educational Curriculum; Elements; Ensure; Evaluation; Exposure to; Faculty; Fostering; Frequencies; Funding; Future; Gender; Generations; Goals; Grant; Health; Incubators; Individual; Informatics; Institution; K-Series Research Career Programs; Manuscripts; Medicine; Mentors; Mentorship; Minority Women; Modeling; Modernization; NCI Scholars Program; Physicians; Program Development; Program Evaluation; Research; Research Personnel; Research Project Grants; Research Training; Resources; Role; Science; Scientist; Secure; Series; Structure; Team Process; Technology; Texas; Thinking; Time; TimeLine; Training; Training Programs; Training and Infrastructure; Translational Research; Translations; Vocational Guidance; Woman; base; career; career development; community engagement; design; empowered; ethnic minority; externship; improved; innovation; interdisciplinary collaboration; peer; peer coaching; pre-clinical research; programs; racial and ethnic; recruit; success; theories; tool; translational medicine; translational pipeline

The UT Southwestern Center for Translational Medicine's (CTM) KL2 Scholars Program already has a proven track record for growing a new generation of Scholars who have become leaders in clinical and translational research (CTR). Our KL2 program, with an ethos of continuous improvement based on metrics and changing needs, has been a model of unique and centralized CTR training in our Hub. Our training curriculum has been streamlined and modernized, and the diversity of our Scholars across all important domains has greatly increased. In the new grant cycle, we will elevate our KL2 program to the next level through innovative programming and cost sharing of CTSA, institutional and hub resources. We will appoint three new KL2 Scholars per year for a two-year term (ongoing total of six/year). KL2 Scholars will engage in mentored research training, take formal coursework and short nanocourses on emerging CTR topics, and submit manuscripts and grant proposals to secure individual career development and/or research grants (K2K and K2R conversion, respectively) in a timely manner, to minimize the career-disrupting “K-cliff.” Careful program evaluation will guide us to restructure elements further to increase the diversity of those we train and broaden the disciplines and institutions from which the Scholars are recruited. The new KL2 plan proposed here is significant and innovative. We will strategically leverage CTSA core and institutional resources to broaden the KL2 program's impact and provide CTR training to an expanding pool of biomedical workforce. The four Aims are integrated through our unique culturally-aware Tiered Mentorship Model, which includes mentorship by primary and secondary research mentors, program directors, near-peer mentors, and Scholar self-mentoring. We propose: Aim 1. Ensure personalized research career development, with customization by a faculty-level Curriculum Navigator and a longitudinal training roadmap; Aim 2. Catalyze collaboration and innovation by launching team science, community engagement, innovator studios and women in technology programs; Aim 3. Promote K2R conversion to independent investigators by strengthening longitudinal K2R progression along the K2R roadmap, creating an Interdiscipinary Sandwich Junior Mentor-in- Training Program and a CTR-Scientific Management program to address unique needs of junior CTR PIs; Aim 4. Expand and strengthen the diverse CTR investigator pipeline by providing CTR training to existing underrepresented trainee career development programs. Impact: Institutional resources will be leveraged to expand the KL2's footprint and enlarge the CTR Scholar community. Rigorous evaluation metrics will be used to enable us to improve our program iteratively. Our forward-thinking and integrated training paradigm will greatly expand the number of Scholars armed with the tools for success and empowered to anticipate and adapt effectively to become CTR leaders of the future.

UT西南转化医学中心（CTM）KL 2学者计划已经证明了 培养新一代学者的良好记录，这些学者已成为临床和翻译领域的领导者 研究（CTR）。我们的KL 2计划，具有基于指标和不断变化的持续改进的精神 根据客户的需求，我们的中心一直是独特的集中式CTR培训的典范。我们的培训课程 精简和现代化，我们的学者在所有重要领域的多样性大大 增加在新的资助周期，我们将通过创新的方式将我们的KL 2计划提升到一个新的水平。 CTSA、机构和中心资源的方案编制和费用分摊。我们将任命三名新的KL 2 学者每年为期两年（正在进行的总共六个/年）。KL 2学者将参与指导 研究培训，参加关于新兴CTR主题的正式课程和简短的纳米课程，并提交 手稿和赠款提案，以确保个人职业发展和/或研究赠款（K2 K和 K2 R转换，分别）及时，以尽量减少破坏职业生涯的“K悬崖”。精心策划 评估将指导我们进一步重组要素，以增加我们培训和扩大的人员的多样性 招募学者的学科和机构。这里提出的新KL 2计划是 重要和创新。我们将战略性地利用CTSA的核心和机构资源， KL 2计划的影响，并为不断扩大的生物医学劳动力提供CTR培训。四 目标通过我们独特的文化意识分层导师模式整合，其中包括 初级和中级研究导师，项目主任，近同行导师和学者的指导 自我指导我们建议：通过定制确保个性化的研究职业发展 通过学院级课程导航和纵向培训路线图;目标2.促进协作 通过启动团队科学、社区参与、创新者工作室和女性参与， 技术方案;目标3。促进K2 R向独立调查员的转变， 纵向K2 R进展沿着K2 R路线图，创建一个跨学科三明治初级导师， 培训计划和CTR科学管理计划，以满足初级CTR PI的独特需求;目标 4.通过向现有的CTR研究者提供CTR培训，扩大和加强多样化的CTR研究者渠道 代表性不足的受训人员职业发展方案。影响：将利用机构资源， 扩大KL 2的足迹，扩大CTR学者社区。将使用严格的评价标准 使我们能够不断改进我们的项目。我们的前瞻性思维和综合培训模式将 大大增加了学者的数量，他们拥有成功的工具，并有能力预测和 有效地适应成为未来的CTR领导者。