Summer Environmental Health Sciences Training Program

夏季环境健康科学培训计划

• 批准号: 10469317
• 负责人: Matthew C Cave
• 金额: $ 5.12万
• 依托单位: UNIVERSITY OF LOUISVILLE
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-08-13 至 2027-02-28
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10469317
• 关键词: Authorship; Award; Chemical Exposure; Chronic Disease; Clinical; Clinical Research; Conflict of Interest; Data; Diabetes Mellitus; Education; Eligibility Determination; Environment; Environmental Health; Funding; Grant; Health; IACUC; Institutional Review Boards; Laboratories; Malignant Neoplasms; Medical; Medical Students; Mentors; Mentorship; Metabolism; National Institute of Environmental Health Sciences; Obesity; Outcome; Peer Review; Persons; Physicians; Plagiarism; Positioning Attribute; Public Health; Publications; Reproducibility; Research; Research Project Grants; Residencies; Scientist; Specialist; Structure; Student recruitment; Students; Training; Training Programs; Training Support; Translational Research; Vertebrates; Work; design; disadvantaged background; experience; fabrication; health science research; hormone regulation; human subject; interest; medical schools; meetings; non-alcoholic fatty liver disease; peer; posters; programs; responsible research conduct; skills; summer student; symposium; underrepresented minority student

Abstract: This proposal is a competing renewal application for a T35 short term medical student summer training program in environmental health science research that has been funded by NIEHS for 15 years. The Specific Aims are: 1) To provide hands-on training in basic and clinical environmental health-based research to medical students in a structured, mentored environment; 2) To provide an interactive, educational experience that introduces medical students to the fundamental skills necessary for basic, translational, and clinical Environmental Health Sciences-based research. The Distinction in Research Track (DIR), a feature added in the previous award period, enhances training for our students to function as environmental health sciences specialists in an academic health center setting. This NIEHS T35 training program encourages students to participate in the DIR for a continued longitudinal research experience in the 2nd – 4th years of medical training, allowing them to develop research-oriented skills to complete a clinical or translational research project in the third/fourth years. Publication of peer-reviewed articles, as some trainees have achieved, as well as the strength of residency training and first permanent position as physician-scientists are tracked as outcomes. The program will support training of 8 second year medical students in environmental health sciences research topics related to chemical exposure induced chronic diseases including diabetes, non-alcoholic fatty liver disease, obesity, cancer and hormonal regulation of metabolism. UofL medical students in the top half of the first year class choose from research projects submitted by 23 mentors in the Schools of Medicine and Public Health (ranking them 1-5 for interest). Trainees to be appointed to the T35 training grant are selected after in- person meetings between trainees and mentors to assure `fit'. A successful effort has been made to recruit students from underrepresented minorities and disadvantaged backgrounds. During the 11-week summer training, students work with mentors on their research project in clinical or laboratory settings and complete training in the Responsible Conduct of Research (topics include: reproducibility, fabrication and falsification of data, plagiarism, managing scientific data, publication practices, mentorship, responsible authorship, stewardship, conflict of interest). Trainees working with human subjects complete human subject and IRB training prior to beginning their research. Trainees who use vertebrate animals in mentors' labs complete and pass IACUC training courses. All trainees will attend a weekly “Environmental Health Sciences Conference” designed to introduce clinical and translational research in environmental health sciences to T35 trainees. The conference culminates with each Trainee presenting his/her research project to peers and mentors. Trainees also present the results of their research as posters with peers at a School of Medicine week-long research celebration that includes nationally recognized physician-scientists as keynote speakers. Poster contest Winners are eligible to attend the National Student Research Forum the following Spring.

摘要： 这项提案是T35医科学生短期暑期培训的竞争性续签申请 NIEHS资助了15年的环境健康科学研究计划。具体的 目标是：1)向医学界提供以环境健康为基础的基础和临床研究的实践培训 学生在结构化、有指导的环境中学习；2)提供互动的教育体验 向医学生介绍基本、翻译和临床所需的基本技能 基于环境健康科学的研究。研究跟踪(DIR)中的区别，这是添加到 上一个获奖期，加强了我们的学生作为环境健康科学的培训 学术健康中心环境中的专家。NIEHS T35培训计划鼓励学生 参加DIR，在2-4年的医学培训中继续纵向研究经验， 允许他们发展以研究为导向的技能，以完成临床或转化性研究项目 第三年/第四年。发表同行评议的文章，正如一些受训人员所实现的那样，以及 住院医师培训的强度和作为内科科学家的第一个永久职位被跟踪为结果。 该计划将支持对8名二年级医学生进行环境健康科学研究的培训。 与化学物质暴露引起的慢性疾病相关的主题，包括糖尿病、非酒精性脂肪肝 疾病、肥胖、癌症和新陈代谢的激素调节。UofL医科学生排名上半部分 一年级学生从23名医学院和公立学校导师提交的研究项目中选择 健康(在兴趣方面给他们打1-5分)。将获委任为T35培训补助金的学员将在以下时间后被挑选出来- 实习生和导师之间的面对面会议，以确保“适合”。已经做出了成功的努力来招募 来自代表性不足的少数族裔和弱势背景的学生。在11周的夏天里 培训，学生在临床或实验室环境中与导师合作进行研究项目，并完成 负责任的研究行为培训(主题包括：可重复性、捏造和伪造 数据，剽窃，管理科学数据，出版实践，指导，负责任的作者， 管理、利益冲突)。与人类受试者一起工作的受训者完成人类受试者和IRB 在开始他们的研究之前进行培训。在导师实验室中使用脊椎动物的受训者完成 通过IACUC培训课程。所有学员将参加每周一次的“环境健康科学会议”。 旨在向T35学员介绍环境健康科学方面的临床和转化性研究。这个 会议的高潮是每个受训者向同行和导师介绍他/她的研究项目。实习生 他们还在医学院为期一周的研究中与同行一起张贴海报展示他们的研究结果 庆祝活动包括全国公认的内科医生和科学家作为主旨演讲者。海报大赛 获奖者有资格参加来年春天举行的全国学生研究论坛。