Nanostructured porous silicon for ophthalmic implants

用于眼科植入物的纳米结构多孔硅

• 批准号: nhmrc : 595901
• 负责人: A/Pr Sonja Klebe
• 金额: $ 35.78万
• 依托单位: Flinders University
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2010
• 资助国家: 澳大利亚
• 起止时间: 2010-01-01 至 2013-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/nanostructured-porous-silicon-ophthalmic-implants/76552
• 关键词: Nanostructured; porous; silicon; ophthalmic; implants

Blindness exerts major physical, emotional and economic constraints upon the sufferer. Our goal is to develop novel nanostructured porous silicon-based implants to improve outcomes for patients prone to recurrent episodes of inflammation in the eye, or with visual loss following ocular trauma or infection. Treatments are available, but are not always effective. Porous silicon is a non-toxic, non-inflammatory, biodegradable material that can be loaded with drugs or cells for transfer to the eye.

失明对患者造成了身体、情感和经济上的严重限制。我们的目标是开发新型纳米结构多孔硅基植入物，以改善容易出现眼部炎症复发或眼外伤或感染后视力丧失的患者的预后。治疗是可行的，但并不总是有效的。多孔硅是一种无毒、非炎症、可生物降解的材料，可以装载药物或细胞，用于转移到眼睛。