Development of a mobile health intervention for electronic cigarette use among young adults

开发针对年轻人电子烟使用的移动健康干预措施

基本信息

  • 批准号:
    10449656
  • 负责人:
  • 金额:
    $ 17.28万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2022
  • 资助国家:
    美国
  • 起止时间:
    2022-07-01 至 2024-06-30
  • 项目状态:
    已结题

项目摘要

PROJECT ABSTRACT Despite declines in combustible cigarette smoking among young adults, use of electronic nicotine delivery systems (ENDS), such as e-cigarettes, continues to rise. Young adulthood marks a particularly susceptible time for the experimentation and initiation of substance use behaviors, including tobacco. Further, some who initiate tobacco use with ENDS transition to combustible products, such as cigarettes or marijuana, or become users of multiple products (dual/poly users). Despite the addiction potential of ENDS and high interest in quitting among young adults , there are few resources available to help individuals quit or reduce their use of ENDS. The aim of the proposed research is to develop an evidence-based mobile health (mHealth) text- message based intervention for young adult ENDS and dual (ENDS and cigarette) users (K99 phase 1), and determine whether the intervention is effective in reducing ENDS use (primary outcome) and increasing cessation , quit attempts, and use of nicotine replacement therapy (NRT; secondary outcomes; R00 phase 2). In phase 1 (K99), we will determine intervention content and delivery schedule based on existing evidence- based smoking cessation materials as well as utilize focus groups with young adult ENDS users (both ENDS- only and dual users) to adapt content to an mHealth ENDS-specific intervention. We will then run an initial pilot study with 45 participants to determine intervention feasibility and acceptability. After the pilot intervention, we will conduct additional focus groups with individuals who participated in the pilot to further refine the intervention. In phase 2 (R00), we will conduct a randomized control trial to determine the intervention’s effect on ENDS outcomes. Young adult ENDS and dual users will be randomized to one of three conditions: 1) mHealth ENDS intervention, 2) standard ENDS advice+NRT, or 3) standard advice alone . Standard advice will include a website that will be updated with information on products/safety and strategies for ENDS cessation as information evolves over the course of the study. Participants in the mHealth condition will complete a 6- week text-message based intervention with content tailored based on 1) motivation to quit ENDS, 2) whether an individual uses ENDS only or is a dual user of tobacco products, and 3) target quit date. Participants will complete an assessment of ENDS behaviors, quit attempts, and use of NRT at 3-month follow-up. ENDS use frequency will be the primary outcome , while biochemically verified 7-day point prevalence abstinence, NRT use, and quit attempts will be the secondary outcomes of interest. This study’s findings will inform emerging ENDS intervention literature, an area where a clear evidence base is currently lacking, and whether a mHealth intervention can impact young adults’ ENDS cessation, behaviors, and barriers to NRT use. This project will serve to provide valuable mentorship and training complementary to the proposed research to facilitate Dr. Brett’s transition to an independently-funded investigator and clinical addiction and tobacco control scientist.
项目摘要 尽管年轻人吸烟的可燃性香烟数量有所下降,但电子尼古丁输送的使用 电子烟等末端系统(ENDS)的使用率持续上升。年轻的成年期标志着一个特别易受影响的 实验和开始物质使用行为的时间,包括烟草。此外,一些谁 开始使用烟草与ENDS过渡到可燃产品,如香烟或大麻,或成为 多种产品的用户(双/多用户)。尽管ENDS有成瘾的可能性 以及对 年轻人戒烟 ,很少有资源可以帮助个人戒烟 或减少使用 形接头.拟议研究的目的是开发一个基于证据的移动的健康(mHealth)文本- 针对年轻成人ENDS和双重(ENDS和香烟)使用者的基于信息的干预(K99第1阶段),以及 确定干预是否有效, 减少ENDS的使用(主要结局), 停止 戒烟尝试和尼古丁替代疗法的使用(NRT;次要结局; R 00第2阶段)。 在第一阶段(K99),我们将根据现有证据确定干预内容和实施时间表- 基于戒烟材料,并利用重点小组与年轻的成年人ENDS用户(两个ENDS- 只有和双重用户),以适应内容的mHealth ENDS特定的干预。然后我们将运行一个初始试点 研究与 45 参与者确定干预的可行性和可接受性。在试点干预后,我们 将与参与试点的个人进行更多的焦点小组讨论,以进一步完善 干预在第2阶段(R 00),我们将进行随机对照试验,以确定干预的效果 结束的结果。年轻成人ENDS和双重使用者将被随机分配至 三 条件:1) 移动健康结束干预, 2)标准ENDS建议+NRT,或3)仅标准建议 .标准建议将 包括一个网站,该网站将更新有关产品/安全性和终止ENDS策略信息 随着信息在研究过程中的发展。在mHealth条件下的参与者将完成一个6- 一周基于短信的干预,内容基于1)戒烟的动机,2)是否 个体仅使用ENDS或是烟草产品的双重使用者,和3)目标戒烟日期。参与者将 在3个月随访时完成对ENDS行为、戒烟尝试和NRT使用的评估。端 使用 频率将是主要结果 ,而生化验证的7天点患病率禁欲,NRT 使用和戒烟尝试将是次要的结果。这项研究的结果将告知新兴的 结束干预文献,一个目前缺乏明确证据基础的领域,以及移动健康是否 干预可以影响年轻人的ENDS停止,行为和NRT使用障碍。该项目将 提供宝贵的指导和培训,以补充拟议的研究,以促进博士。 布雷特的过渡到一个独立资助的调查员和临床成瘾和烟草控制科学家。

项目成果

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Emma Brett其他文献

Emma Brett的其他文献

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{{ truncateString('Emma Brett', 18)}}的其他基金

Development of a mobile health intervention for electronic cigarette use among young adults
开发针对年轻人电子烟使用的移动健康干预措施
  • 批准号:
    10640966
  • 财政年份:
    2022
  • 资助金额:
    $ 17.28万
  • 项目类别:

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