Stanford Undergraduate URM Summer Cardiovascular Research Program

项目总结 该R25计划的目标是增加未被充分代表的少数族裔(URM)的数量 通过为URM本科生提供短期指导来促进心血管研究的职业发展 斯坦福大学医学院心血管研究所(CVI)成员的实验室研究经验。 在美国，心血管疾病是导致死亡和残疾的主要原因。然而，这些疾病确实 并不是平等地影响所有美国亚群。非洲裔美国人和拉美裔/西班牙裔美国人经历了 心脏病或中风导致的死亡或残疾风险显著增加。非裔美国人、拉丁裔/西班牙裔 美国人、美洲原住民和一些亚裔亚群也经历了更高的患病风险 2型糖尿病本身就是心血管疾病的危险因素。这些群体构成了一个不断增长的 美国人口的一小部分，从历史上看，诊所和医学研究都没有为他们提供足够的医疗服务。 由于招募和保留方面的问题，非洲裔美国人、拉美裔/西班牙裔美国人和 美洲原住民在医学和基础心血管研究中的代表性明显不足 劳动力。非洲人、拉丁裔/西班牙裔和美国原住民医疗和研究专业人员的短缺 导致高危少数群体缺乏医疗服务，因为人们更有可能寻求 从属于自己种族群体的个人那里得到照顾。在心血管研究方面， 少数族裔研究人员更有可能关注并意识到环境、遗传和行为 不同群体之间的差异会影响诊断和治疗。已经证明，参与 有指导的研究增加了本科生URM学生作为科学家的认同感和坚持不懈的程度 在学术和医学研究生涯中。然而，因为有更多的本科生寻求研究 很多本科生，特别是本科生，缺乏足够的经验 在学术实验室进行独立研究的机会。 R25将：1)为本科生提供心血管方面的技术培训和经验 研究；2)为城市管理机构提供心血管研究导师和榜样；以及3)建立 斯坦福医学与地方和全国性少数民族服务机构的关系。史丹福 一般的医学，特别是CVI，在心血管研究方面都以卓越而闻名。该计划 参与此R25的董事(Wu、De Jesse Perez和Red-Horse)和计划学院，其中许多人 他们自己也有最先进的研究项目，涵盖人口结果、临床和 翻译和基础心血管研究，并欢迎有机会指导R25学员。同舟共济 他们有指导专业知识和资源来支持R25学员，尽管是在这个项目中。

PROJECT SUMMARY The goal of this R25 program is to increase the numbers of underrepresented minorities (URMs) pursuing careers in cardiovascular research by providing URM undergraduate students with a short-term mentored research experience in the laboratories of members of Stanford Medicine’s Cardiovascular Institute (CVI). Cardiovascular diseases are the leading causes of death and disability in the US. However, these diseases do not affect all US subpopulations equally. African Americans and Latino/Hispanic Americans experience a significantly higher risk of death or disability from heart disease or stroke. African Americans, Latino/Hispanic Americans, Native Americans, and some Asian sub-populations also experience increased risk of developing type 2 diabetes, which is itself a risk factor for cardiovascular diseases. These groups, which constitute a growing fraction of the US population, have historically been medically underserved by both clinics and medical research. Due to problems with both the recruitment and retention, African Americans, Latino/Hispanic Americans and Native Americans are significantly underrepresented in the medical and basic cardiovascular research workforce. This shortage of African, Latino/Hispanic, and Native American medical and research professionals contributes to the scarcity of medical care for at risk minority populations because people are more likely to seek out care from individuals that are members of their own ethnic group. In terms of cardiovascular research, minority researchers are more likely to focus on and be aware of environmental, genetic, and behavioral variations between groups that can affect diagnosis and treatment. It has been shown that participation in mentored research increases the degree to which undergraduate URM students identify as scientists and persist in academic and medical research career. However, because there are more undergraduates seeking research experiences than there are available positions, many undergraduate students, particularly URMs, lack the opportunity to perform independent research in an academic lab. This R25 will: 1) provide undergraduate URMs with technical training and experience in cardiovascular research; 2) provide URMs with cardiovascular researcher mentors and role models; and 3) build relationships between Stanford Medicine and local & national minority-serving institutions. Stanford Medicine in general and the CVI in particular are known for excellence in cardiovascular research. The Program Directors (Wu, de Jesus Perez, and Red-Horse) and Program Faculty involved in this R25, many of whom are themselves URMs, have state-of-the-art research programs spanning population outcome, clinical and translational, and basic cardiovascular research, and welcome the opportunity to mentor R25 trainees. Together they have the mentoring expertise and the resources to support R25 trainees though in this program.