Stanford Undergraduate URM Summer Cardiovascular Research Program

项目摘要 这个R25计划的目标是增加代表性不足的少数民族（URM）的数量， 通过为URM本科生提供短期指导， 在斯坦福大学医学心血管研究所（CVI）成员的实验室进行研究的经验。 心血管疾病是美国死亡和残疾的主要原因。然而，这些疾病 并不会对所有美国亚群造成同等影响。非裔美国人和拉丁裔/西班牙裔美国人经历了一个 因心脏病或中风而死亡或残疾的风险明显更高。非裔美国人，拉丁裔/西班牙裔 美国人，美洲原住民和一些亚洲亚群也经历了发展的风险增加， 2型糖尿病本身就是心血管疾病的危险因素。这些群体， 美国人口的一小部分，历史上一直没有得到医疗服务的诊所和医学研究。 由于招聘和留住人才的问题，非洲裔美国人、拉丁裔/西班牙裔美国人和 美洲原住民在医学和基础心血管研究中的代表性明显不足 劳动力非洲、拉丁美洲/西班牙裔和美洲原住民医疗和研究专业人员的短缺 导致处于危险中的少数群体的医疗保健稀缺，因为人们更有可能寻求 照顾自己的种族群体的成员。在心血管研究方面， 少数民族研究人员更有可能关注并意识到环境，遗传和行为 组间差异可能影响诊断和治疗。事实表明，参与 指导研究提高了本科URM学生作为科学家的认同程度，并坚持 在学术和医学研究生涯中。然而，由于有更多的本科生寻求研究， 经验比有可用的职位，许多本科生，特别是URMs，缺乏 有机会在学术实验室进行独立研究。 该R25将：1）为本科URM提供心血管技术培训和经验 研究; 2）为URM提供心血管研究人员导师和榜样;以及3）建立 斯坦福大学医学与地方和国家少数民族服务机构之间的关系。斯坦福大学 医学，特别是CVI，以其在心血管研究方面的卓越而闻名。程序 董事（吴，德耶稣佩雷斯，和红马）和计划教师参与这一R25，其中许多人是 URM本身拥有最先进的研究项目，涵盖人口结局、临床和 翻译和基础心血管研究，并欢迎有机会指导R25学员。一起 他们有指导的专业知识和资源，以支持R25学员虽然在这个程序。

PROJECT SUMMARY The goal of this R25 program is to increase the numbers of underrepresented minorities (URMs) pursuing careers in cardiovascular research by providing URM undergraduate students with a short-term mentored research experience in the laboratories of members of Stanford Medicine’s Cardiovascular Institute (CVI). Cardiovascular diseases are the leading causes of death and disability in the US. However, these diseases do not affect all US subpopulations equally. African Americans and Latino/Hispanic Americans experience a significantly higher risk of death or disability from heart disease or stroke. African Americans, Latino/Hispanic Americans, Native Americans, and some Asian sub-populations also experience increased risk of developing type 2 diabetes, which is itself a risk factor for cardiovascular diseases. These groups, which constitute a growing fraction of the US population, have historically been medically underserved by both clinics and medical research. Due to problems with both the recruitment and retention, African Americans, Latino/Hispanic Americans and Native Americans are significantly underrepresented in the medical and basic cardiovascular research workforce. This shortage of African, Latino/Hispanic, and Native American medical and research professionals contributes to the scarcity of medical care for at risk minority populations because people are more likely to seek out care from individuals that are members of their own ethnic group. In terms of cardiovascular research, minority researchers are more likely to focus on and be aware of environmental, genetic, and behavioral variations between groups that can affect diagnosis and treatment. It has been shown that participation in mentored research increases the degree to which undergraduate URM students identify as scientists and persist in academic and medical research career. However, because there are more undergraduates seeking research experiences than there are available positions, many undergraduate students, particularly URMs, lack the opportunity to perform independent research in an academic lab. This R25 will: 1) provide undergraduate URMs with technical training and experience in cardiovascular research; 2) provide URMs with cardiovascular researcher mentors and role models; and 3) build relationships between Stanford Medicine and local & national minority-serving institutions. Stanford Medicine in general and the CVI in particular are known for excellence in cardiovascular research. The Program Directors (Wu, de Jesus Perez, and Red-Horse) and Program Faculty involved in this R25, many of whom are themselves URMs, have state-of-the-art research programs spanning population outcome, clinical and translational, and basic cardiovascular research, and welcome the opportunity to mentor R25 trainees. Together they have the mentoring expertise and the resources to support R25 trainees though in this program.