Mobile Health Intervention to Increase Substance-Free Activities During Alcohol Treatment

移动健康干预以增加酒精治疗期间的无物质活动

• 批准号: 10473817
• 负责人: Lidia Meshesha
• 金额: $ 18.48万
• 依托单位: UNIVERSITY OF CENTRAL FLORIDA
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-20 至 2025-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10473817
• 关键词: Abstinence; Affect; Alcohol consumption; Alcohols; Applications Grants; Behavior; Behavior Therapy; Behavioral; Car Phone; Cardiovascular Diseases; Categories; Cognitive Therapy; Data; Data Analyses; Development; Development Plans; Ecological momentary assessment; Effectiveness; Employment; Enhancement Technology; Environment; Evaluation; Feedback; Focus Groups; Funding; Goals; Health; Health Personnel; Human; Individual; Injury; Intervention; Interview; Lead; Life; Link; Liver diseases; Maintenance; Malignant Neoplasms; Mentored Patient-Oriented Research Career Development Award; Mentors; Metadata; Methodology; Monitor; Moods; National Institute on Alcohol Abuse and Alcoholism; Neurobiology; Outpatients; Participant; Patient Monitoring; Patient Self-Report; Patients; Phase; Psychological reinforcement; Public Health; Questionnaires; Randomized; Recovery; Relapse; Religion; Reporting; Research; Research Personnel; Research Training; Resources; Rewards; Role; Sampling; Series; Social Network; Suggestion; Technology; Time; Training; Treatment Efficacy; Treatment outcome; acceptability and feasibility; active control; alcohol abstinence; alcohol abuse therapy; alcohol testing; alcohol use disorder; base; brief advice; career; career development; cost; design; drinking; efficacy testing; experience; hands-on learning; improved; improved outcome; innovation; interest; mHealth; mobile computing; novel; pilot trial; preventable death; prototype; reduced substance use; reinforcer; relapse risk; research and development; smartphone Application; sobriety; social cognitive theory; substance misuse; therapy design; treatment as usual; treatment center; treatment effect; usability

PROJECT SUMMARY/ ABSTRACT Alcohol Use Disorder (AUD) is a highly prevalent and significant public health problem. Behavioral treatments based in the principles of social learning theory and cognitive behavior therapy have been developed and tested for AUD, yet effect sizes are relatively small and rates of relapse following treatment are high. Theoretically informed adjunctive interventions may help to enhance the effects of extant AUD treatments. In particular, evidence suggests that environments lacking in substance-free (SF) activities contribute to the development and maintenance of AUD and that the availability of rewarding SF activities may serve as viable alternatives to compete with alcohol use. Building on the advantages of accessibility and low-cost option afforded by the use of mobile technology, this K23 Mentored Patient-Oriented Research Career Development Award proposal outlines a well-integrated research and training plan to investigate a mobile health intervention to increase engagement in rewarding SF activities among patients in AUD treatment. This proposed research aims to develop and evaluate a mobile phone ecological momentary assessment plus ecological momentary intervention (EMA+EMI; entitled: mobile – Rewarding Activity Centered Treatment (m-ReACT)) app to augment existing AUD treatment. The m-ReACT app will monitor self-reported rewarding SF activity engagement in real-time and deliver personalized feedback that encourages participants to engage in highly rewarding activities that are goal-oriented and support positive treatment outcomes. This proposed intervention will be developed in two phases. Phase 1 will develop the m-ReACT app through a series of focus groups and usability studies and Phase 2 will evaluate its efficacy in randomized control pilot trial with a sample of 50 AUD patients who have recently initiated outpatient AUD treatment. Participants in the pilot RCT will be randomly assigned to either the m-ReACT condition or an active control condition. It is hypothesized that m-ReACT will result in increased rates of percent days of alcohol abstinence and increased reinforcement from SF activities. This research plan provides the PI the essential hands-on learning and mentored training in development and delivery of technology enhanced interventions, design and implementation of EMA+EMI platforms, qualitative methodology, and advanced statistical approaches. Successful completion of this K23 award will provide the PI essential training to be able to transition to an independent investigator role examining novel interventions to enhance AUD treatment. This proposal is highly consistent with NIAAA’s current funding priorities of funding projects that use mobile technology to improve the effectiveness, accessibility, and use of behavioral interventions for AUD.

项目概要/摘要 酒精使用障碍（AUD）是一个非常普遍且重要的公共卫生问题。行为治疗 基于社会学习理论和认知行为疗法的原理已经发展和 对 AUD 进行了测试，但效果相对较小，并且治疗后复发率很高。 从理论上讲，辅助干预措施可能有助于增强现有 AUD 治疗的效果。在 特别是，有证据表明，缺乏无物质（SF）活动的环境会导致 AUD 的开发和维护以及奖励性 SF 活动的可用性可能是可行的 与酒精使用竞争的替代品。建立在可访问性和低成本选择的优势之上 通过使用移动技术，K23 指导的以患者为导向的研究职业发展 奖励提案概述了一项综合研究和培训计划，以调查移动健康干预措施 增加 AUD 治疗患者对奖励 SF 活动的参与度。这项拟议的研究 旨在开发和评估手机生态瞬时评估+生态瞬时 干预（EMA+EMI；标题：移动 – 奖励活动中心治疗 (m-ReACT)）应用程序 增强现有的 AUD 治疗。 m-ReACT 应用程序将监控自我报告的奖励 SF 活动 实时参与并提供个性化反馈，鼓励参与者高度参与 奖励以目标为导向并支持积极治疗结果的活动。这项拟议的干预措施 将分两期开发。第一阶段将通过一系列焦点小组和 可用性研究和第 2 阶段将在随机对照试点试验中评估其功效，样本为 50 澳元 最近开始门诊 AUD 治疗的患者。试点随机对照试验的参与者将是随机的 分配给 m-ReACT 条件或主动控制条件。假设 m-ReACT 将 导致戒酒百分比天数增加，并增加 SF 活动的强化。 该研究计划为 PI 提供了必要的实践学习和开发方面的指导培训 提供技术增强干预措施、EMA+EMI 平台的设计和实施、定性 方法论和先进的统计方法。成功完成此 K23 奖项将提供 PI 进行必要的培训，以便能够过渡到独立调查员的角色，检查新的干预措施 加强澳元治疗。该提案与NIAAA当前的资助重点高度一致 使用移动技术来提高行为的有效性、可访问性和使用的项目 澳元的干预措施。