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Mobile Health Intervention to Increase Substance-Free Activities During Alcohol Treatment

移动健康干预以增加酒精治疗期间的无物质活动

基本信息

批准号：
10681252
负责人：
Lidia Meshesha
金额：
$ 15.9万
依托单位：
UNIVERSITY OF CENTRAL FLORIDA
依托单位国家：
美国
项目类别：
财政年份：
2020
资助国家：
美国
起止时间：
2020-09-20 至 2025-08-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10681252
关键词：
Abstinence Affect Alcohol consumption Alcohols Applications Grants Behavior Behavior Therapy Behavioral Cardiovascular Diseases Categories Cellular Phone Cognitive Therapy Data Data Analyses Development Development Plans Ecological momentary assessment Effectiveness Employment Enhancement Technology Environment Evaluation Feedback Focus Groups Funding Goals Health Health Personnel Human Individual Injury Intervention Interview Life Link Liver diseases Maintenance Malignant Neoplasms Mentored Patient-Oriented Research Career Development Award Mentors Metadata Methodology Monitor Moods National Institute on Alcohol Abuse and Alcoholism Neurobiology Outpatients Participant Patient Monitoring Patient Self-Report Patients Phase Psychological reinforcement Public Health Questionnaires Randomized Recovery Relapse Religion Reporting Research Research Personnel Resources Rewards Role Sampling Series Social Network Suggestion Technology Time Training Treatment Efficacy Treatment outcome acceptability and feasibility active control alcohol abstinence alcohol abuse therapy alcohol testing alcohol use disorder brief advice career career development cost design drinking efficacy testing experience hands-on learning high reward improved improved outcome innovation interest mHealth mobile computing novel pilot trial preventable death prototype reduced substance use reinforcer relapse risk research and development smartphone application sobriety social cognitive theory substance misuse therapy design treatment as usual treatment center treatment effect usability

项目摘要

PROJECT SUMMARY/ ABSTRACT Alcohol Use Disorder (AUD) is a highly prevalent and significant public health problem. Behavioral treatments based in the principles of social learning theory and cognitive behavior therapy have been developed and tested for AUD, yet effect sizes are relatively small and rates of relapse following treatment are high. Theoretically informed adjunctive interventions may help to enhance the effects of extant AUD treatments. In particular, evidence suggests that environments lacking in substance-free (SF) activities contribute to the development and maintenance of AUD and that the availability of rewarding SF activities may serve as viable alternatives to compete with alcohol use. Building on the advantages of accessibility and low-cost option afforded by the use of mobile technology, this K23 Mentored Patient-Oriented Research Career Development Award proposal outlines a well-integrated research and training plan to investigate a mobile health intervention to increase engagement in rewarding SF activities among patients in AUD treatment. This proposed research aims to develop and evaluate a mobile phone ecological momentary assessment plus ecological momentary intervention (EMA+EMI; entitled: mobile – Rewarding Activity Centered Treatment (m-ReACT)) app to augment existing AUD treatment. The m-ReACT app will monitor self-reported rewarding SF activity engagement in real-time and deliver personalized feedback that encourages participants to engage in highly rewarding activities that are goal-oriented and support positive treatment outcomes. This proposed intervention will be developed in two phases. Phase 1 will develop the m-ReACT app through a series of focus groups and usability studies and Phase 2 will evaluate its efficacy in randomized control pilot trial with a sample of 50 AUD patients who have recently initiated outpatient AUD treatment. Participants in the pilot RCT will be randomly assigned to either the m-ReACT condition or an active control condition. It is hypothesized that m-ReACT will result in increased rates of percent days of alcohol abstinence and increased reinforcement from SF activities. This research plan provides the PI the essential hands-on learning and mentored training in development and delivery of technology enhanced interventions, design and implementation of EMA+EMI platforms, qualitative methodology, and advanced statistical approaches. Successful completion of this K23 award will provide the PI essential training to be able to transition to an independent investigator role examining novel interventions to enhance AUD treatment. This proposal is highly consistent with NIAAA’s current funding priorities of funding projects that use mobile technology to improve the effectiveness, accessibility, and use of behavioral interventions for AUD.

项目摘要/摘要酒精使用障碍(AUD)是一个非常普遍和重要的公共卫生问题。行为治疗基于社会学习理论和认知行为疗法的原理已经发展起来，对AUD进行了测试，但效果规模相对较小，治疗后复发率较高。理论上知情的辅助干预可能有助于增强现有AUD治疗的效果。在……里面特别是，有证据表明，缺乏无物质(SF)活动的环境有助于开发和维持澳元，以及提供奖励的科普活动可能是可行的与酒精使用竞争的替代品。以无障碍和低成本选项的优势为基础通过使用移动技术，K23指导了以患者为导向的研究职业发展奖励方案概述了一项完美整合的研究和培训计划，以调查移动健康干预在AUD治疗的患者中增加对奖励SF活动的参与。这项拟议的研究旨在开发和评估手机生态瞬时评估加生态瞬时干预(EMA+EMI；标题：以移动为奖励的以活动为中心的治疗(M-Reaction))APP 加强现有的AUD治疗。M-Reaction应用程序将监控自我报告的奖励SF活动实时参与并提供个性化反馈，鼓励参与者高度参与奖励以目标为导向并支持积极治疗结果的活动。这项拟议的干预将分两个阶段开发。第一阶段将通过一系列焦点小组和可用性研究和第二阶段将在随机对照试点试验中评估其有效性，样本为50澳元最近开始进行AUD门诊治疗的患者。试点RCT的参与者将是随机的被分配到m反应条件或主动控制条件。据推测，m反应将结果是酒精戒断天数百分比增加，SF活动增强。这项研究计划为PI提供了必要的实践学习和指导培训，以发展和提供技术增强的干预措施，设计和实施EMA+EMI平台，定性方法和先进的统计方法。成功完成这项K23奖项将提供PI 能够过渡到独立调查员角色的基本培训，以审查新的干预措施加强AUD治疗。这项提议与NIAAA目前的资金优先事项高度一致使用移动技术来提高行为的有效性、可访问性和使用率的项目对澳元的干预。