Virtual Activities of Living for Occupational Rehabilitation

项目总结/摘要 介绍：职业康复生活虚拟活动（VALOR）SBIR计划将支持 远程医疗交付和远程监测上肢（UE）中风康复的做法， 虚拟日常生活活动（ADL）和工具性ADL（IADL）。VALOR系统与地面结合- 打破了无限制的虚拟现实（VR）头显技术和深度学习运行时3D运动跟踪， 现有的一套数字ADL/IADL内容，使功能，重复性任务的做法，在家里与远程医疗 支持.一个关键的技术突破是无标记跟踪，它采用内置在低成本VR中的摄像头。 头戴式耳机，使患者能够使用其受影响的UE手动参与虚拟职业。 VALOR I期项目通过由以下人员进行的试点研究追求两个主要研究目标： 杜克大学：（1）评估UE沉浸式VR ADL/IADL实践的可用性和技术接受度 老年中风患者的治疗;（2）建立沉浸式虚拟ADL/IADL实践的有效性， 跟踪患者的UE运动状态以实现远程健康反馈和监测。第一阶段技术工作 包括将用于实时UE跟踪的运行时神经网络与现有的一套虚拟 ADL/IADL（最初为使用Kinect的非沉浸式基于PC的系统开发），以支持沉浸式 VR使用低成本的独立式、不受束缚的头戴式耳机（无需PC、显示器和额外的传感器）。 待解决的问题：COVID-19大流行暴露出严重缺乏提供 通过远程医疗进行循证UE干预。需要创新的解决方案，使患者能够安全地 在家参与治疗师监控的治疗计划。在超过795，000人中， 在美国，每年因中风住院的患者患有UE功能的慢性缺陷[1]，[2]。现有临床 用于沉浸式VR的治疗系统对于在患者家中使用来说太昂贵、复杂和/或笨重。游戏 游戏机，exergames，或马虎，非证据为基础的虚拟现实技术的适应不解决 在日常生活活动中实现功能独立所需的综合运动和认知技能。 长期目标：改善神经损伤患者的结局和功能独立性。 第一阶段概述：第一阶段将生产一个原型VALOR系统，该系统由一个移动的软件组成 在不受限制的Oculus Quest 2上运行的应用程序（即，无线）VR耳机。至少3种沉浸式ADL/IADL 活动将被充分集成和测试，利用现有的虚拟世界资产库， 沉浸式临床VR系统。杜克大学对中风患者进行的一项试点研究将证明， 可用性和技术接受度，并调查沉浸式体验期间捕获的指标 ADL/IADL实践在UE功能的金标准测量方面具有高标准有效性。 商业机会：VALOR产品准备通过成熟的 营销和分销渠道，以满足对循证远程保健职业治疗的迫切需要。

PROJECT SUMMARY/ABSTRACT Introduction: The Virtual Activities of Living for Occupational Rehabilitation (VALOR) SBIR program will support telehealth delivery and remote monitoring of upper extremity (UE) stroke rehabilitation through the practice of virtual activities of daily living (ADLs) and instrumental ADLs (IADLs). The VALOR system marries ground- breaking untethered virtual reality (VR) headset technology and deep learning runtime 3D motion tracking with an existing suite of digital ADL/IADL content to enable functional, repetitive task practice at home with telehealth support. A key technological breakthrough is markerless tracking that employs cameras built into a low-cost VR headset, enabling patients to manually engage in virtual occupations using their affected UE. The VALOR Phase I program pursues two primary investigational objectives through a pilot study conducted by Duke University: (1) assess the usability and technology acceptance of immersive VR ADL/IADL practice for UE therapy by older adult stroke patients; and (2) establish the validity of immersive virtual ADL/IADL practice for tracking a patient's UE motor status to enable telehealth feedback and monitoring. Technical work in Phase I includes integration of a runtime neural network for real-time UE tracking with an existing suite of virtual ADLs/IADLs (originally developed for a non-immersive, PC-based system using the Kinect) to support immersive VR using a low cost standalone, untethered headset (no PC, no monitor, and no additional sensors required). Problem to be addressed: The COVID-19 pandemic exposed a critical lack of options for delivering an evidence-based UE intervention via telehealth. Innovative solutions are needed to enable patients to safely participate from home in a therapist-monitored therapy program. Approximately 50% of the >795,000 individuals hospitalized due to stroke each year in the U.S. suffer from chronic deficits in UE function [1], [2]. Existing clinical therapy systems for immersive VR are too expensive, complex, and/or bulky for use in patients' homes. Game consoles, exergames, or slipshod, non-evidence-based adaptations of VR technology do not address the integrated motor and cognitive skills required to achieve functional independence in daily living activities. Long-Term Goal: Improved outcomes and functional independence for patients with neurological injury. Phase I Summary: Phase I will produce a prototype VALOR system that consists of a mobile software application that runs on an Oculus Quest 2 untethered (i.e., wireless) VR headset. At least 3 immersive ADL/IADL activities will be fully integrated and tested, leveraging an existing library of virtual world assets from a non- immersive clinical VR system. A pilot study conducted by Duke University with stroke patients will demonstrate usability and technology acceptance, and investigate the hypothesis that metrics captured during immersive ADL/IADL practice will have high criterion validity with respect to gold standard measures of UE function. Commercial Opportunity: The VALOR product is poised to rapidly transition through well-established marketing and distribution channels to meet a critical need for evidence-based telehealth occupational therapy.