Motivating Occupational Virtual Experiences In Therapy for kids
激发儿童治疗中的职业虚拟体验
基本信息
- 批准号:10264174
- 负责人:
- 金额:$ 92.8万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2018
- 资助国家:美国
- 起止时间:2018-04-01 至 2024-08-31
- 项目状态:已结题
- 来源:
- 关键词:AddressAdherenceAffectAwardBlindedBrain InjuriesCerebral PalsyChildChildhoodChildhood strokeClinicalClinical ResearchClinical TrialsComputer softwareDevelopmentDiseaseElementsEvidence based treatmentExerciseGoalsGoldHand functionsHealthcareHemiplegiaHomeHumanImprove AccessInterventionInterviewLearningMarketingMeasuresMedicalModelingMonitorMotionMotivationMotorMotor SkillsMovementNeuronal PlasticityOccupationalOutcomeParentsParticipantPatient ParticipationPatientsPediatric HospitalsPerformancePhasePilot ProjectsPlayProductionProviderPublic HealthQuestionnairesRandomized Controlled TrialsRecoveryRegimenRehabilitation therapyRole playing therapySafetySecureSelf CareSmall Business Innovation Research GrantSpecialistSupervisionSupport SystemSystemTechnologyTestingToyTrainingTraumaUniversitiesUpper ExtremityUser-Computer InterfaceVideo GamesVirginiaVisualbasecohortcommercializationcompliance behaviorconstraint induced movement therapyconstraint induced therapycostcost effectivedashboarddata fusiondesigndosageefficacy studyevidence baseexercise programexperiencehaptic feedbackimprovedimproved outcomeindividual patientindividualized medicineinnovationinnovative technologieskinematicsmixed realitymultisensoryprogramsprototypepsychologicremote monitoringsensorskillsstandard measuresuccesstelehealththerapy adherencetherapy durationtreatment as usualtreatment grouptumorunderserved areausabilityvirtualvirtual world
项目摘要
PROJECT SUMMARY/ABSTRACT
Introduction: The Motivating Occupational Virtual Experiences In Therapy for kids (MOVE-IT) SBIR Phase II
program will support telehealth delivery of intensive rehabilitation for pediatric hemiplegia through smart toy-
enabled games that inspire high-dosage, task-directed upper extremity (UE) movements. Although higher-
dosage training is almost uniformly associated with better outcomes in UE rehabilitation [1], [2], [3], [4], achieving
the repetitions necessary to attain lasting results through neuroplasticity is a formidable challenge. The MOVE-
IT system will employ therapy games that combine virtual- and real-world physical elements to provide a turn-
key solution suitable for both home and clinical use. MOVE-IT will engage patients in repetitive practice,
facilitating an evidence-based approach that integrates proven concepts in constraint-induced movement
therapy (CIMT) and other intensive therapy regimes [5]. This innovative solution employs a multi-sensory smart
toy, advanced game engine, and low-cost motion tracking to create games that promote sustained adherence.
Problem to be Addressed: Pediatric hemiplegia can result from Cerebral Palsy (CP) or acquired brain injury
(including pediatric stroke, trauma, tumor, or other disease), and adversely affect motor functions essential to
self-care, play, exploratory learning, and other daily activities [6]. Existing systems do not currently support
telehealth delivery of the high-dosage, evidence-based therapy required for improvement in UE function.
Long-Term Goals: Provide an effective home exercise program supported by remote guidance and monitoring
of evidence-based treatment for pediatric hemiplegia. Improve patient participation and adherence to an
intensive therapy regimen. Reduce the cost of, and improve access to, state-of-the-art rehabilitation. Provide
validated metrics for remotely tracking patient status and progress.
Phase I Results: Phase I produced a prototype smart toy, two UE therapy mini-games, human kinematics
tracking software, and validated UE motor performance metrics. A pilot study was conducted at the University of
Virginia (UVA) Children’s Hospital involving 10 children with hemiplegia. Analysis confirms the primary Phase I
hypothesis that MOVE-IT generated metrics have high criterion validity with gold-standard measures of UE motor
function. Patient/parent interviews/questionnaires strongly support the technology’s acceptance and usability.
Phase II Summary: MOVE-IT Phase II will produce a commercial system including an enhanced smart toy and
quest-based game software for sustained engagement over a full course of therapy; demonstrate efficacy;
establish safety and usability; and pursue FDA-clearance. Phase II will culminate in a rater-blinded randomized,
controlled trial to investigate efficacy in home use by children with hemiplegia, as measured by change in gold-
standard measures of UE function for a cohort using MOVE-IT compared to a usual care treatment (UCT) group.
Commercial Opportunity: High likelihood of commercialization is supported by Barron Associates’ past
successes in development, clinical trials, FDA-clearance, and marketing of innovative technology for UE therapy.
项目概要/摘要
简介:儿童治疗中的激励性职业虚拟体验 (MOVE-IT) SBIR 第二阶段
该计划将通过智能玩具支持小儿偏瘫强化康复的远程医疗服务
激发高剂量、任务导向的上肢 (UE) 运动的游戏。虽然较高——
剂量训练几乎一致与更好的 UE 康复结果相关 [1]、[2]、[3]、[4],
通过神经可塑性获得持久结果所需的重复是一项艰巨的挑战。行动-
IT系统将采用结合虚拟和现实世界物理元素的治疗游戏来提供回合制治疗。
适合家庭和临床使用的关键解决方案。 MOVE-IT 将使患者参与重复练习,
促进基于证据的方法,将经过验证的概念整合到约束引起的运动中
治疗(CIMT)和其他强化治疗方案[5]。这一创新解决方案采用了多感官智能技术
玩具、先进的游戏引擎和低成本的运动跟踪来创建促进持续坚持的游戏。
要解决的问题:小儿偏瘫可能是由脑瘫(CP)或后天性脑损伤引起的
(包括小儿中风、创伤、肿瘤或其他疾病),并对运动至关重要的功能产生不利影响
自我照顾、玩耍、探索性学习和其他日常活动[6]。现有系统目前不支持
远程医疗提供改善 UE 功能所需的高剂量、循证治疗。
长期目标:提供由远程指导和监控支持的有效家庭锻炼计划
小儿偏瘫的循证治疗。提高患者的参与度和依从性
强化治疗方案。降低最先进康复的成本并改善获得最先进康复的机会。提供
用于远程跟踪患者状态和进展的经过验证的指标。
一期成果:一期生产了一个原型智能玩具、两个UE治疗小游戏、人体运动学
跟踪软件,并验证 UE 电机性能指标。英国大学进行了一项试点研究
弗吉尼亚州 (UVA) 儿童医院涉及 10 名偏瘫儿童。分析证实了第一阶段的主要进展
假设 MOVE-IT 生成的指标对于 UE 电机的黄金标准测量具有高标准有效性
功能。患者/家长访谈/问卷调查强烈支持该技术的接受度和可用性。
第二阶段总结:MOVE-IT 第二阶段将生产一个商业系统,包括增强型智能玩具和
基于任务的游戏软件,可在整个治疗过程中持续参与;证明功效;
建立安全性和可用性;并寻求 FDA 许可。第二阶段将在评估者盲态随机、
对照试验调查偏瘫儿童在家使用的效果,通过金-变化来衡量
使用 MOVE-IT 的队列与常规护理治疗 (UCT) 组相比,UE 功能的标准测量。
商业机会:Barron Associates 过去的经验支持商业化的可能性很高
UE 疗法创新技术的开发、临床试验、FDA 批准和营销方面取得了成功。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Richard J. Adams其他文献
Dynamic regulation of growing domains for elongating and branching morphogenesis in plants
- DOI:
10.1016/j.biosystems.2012.03.004 - 发表时间:
2012-09-01 - 期刊:
- 影响因子:
- 作者:
Lionel G. Harrison;Richard J. Adams;David M. Holloway - 通讯作者:
David M. Holloway
Improving inter-organizational baseline alignment in large space system development programs
改善大型空间系统开发计划中的组织间基线一致性
- DOI:
10.1109/aero.2006.1656167 - 发表时间:
2006 - 期刊:
- 影响因子:0
- 作者:
Donald R. Greer;Laura J. Black;Richard J. Adams - 通讯作者:
Richard J. Adams
(書評論文)Peter Lambert and Andrew Nickson (eds.), The Paraguay Reader: History, Culture, Politics, (Durham: Duke University Press, 2013)
(书评文章)Peter Lambert 和 Andrew Nickson(编辑),《巴拉圭读本:历史、文化、政治》(达勒姆:杜克大学出版社,2013 年)
- DOI:
- 发表时间:
2014 - 期刊:
- 影响因子:0
- 作者:
Dianne T.V. Pawluk;Richard J. Adams;Ryo Kitada;武田和久 - 通讯作者:
武田和久
Properties of Rasch residual fit statistics.
Rasch 残差拟合统计量的属性。
- DOI:
- 发表时间:
2013 - 期刊:
- 影响因子:0
- 作者:
Margaret Wu;Richard J. Adams - 通讯作者:
Richard J. Adams
Automated Plume Sentry Observations During International Space Station Thermal Control System Venting
国际空间站热控制系统通风期间的自动羽流哨兵观测
- DOI:
- 发表时间:
2023 - 期刊:
- 影响因子:1.6
- 作者:
C. Maldonado;A. Ketsdever;R. Balthazor;P. Neal;G. Wilson;M. McHarg;R. Osiander;Richard J. Adams - 通讯作者:
Richard J. Adams
Richard J. Adams的其他文献
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{{ truncateString('Richard J. Adams', 18)}}的其他基金
Virtual Activities of Living for Occupational Rehabilitation
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10382990 - 财政年份:2022
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Glove Rehabilitation Application for Stroke Patients (GRASP)
中风患者手套康复应用 (GRASP)
- 批准号:
9254255 - 财政年份:2016
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Multi-modal Application for the Perception of Spaces (MAPS)
空间感知的多模态应用(MAPS)
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8314498 - 财政年份:2013
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A New Approach to Vision Therapy Based on Naturalistic 3-D Computer Gaming
基于自然 3D 计算机游戏的视觉治疗新方法
- 批准号:
9455693 - 财政年份:2010
- 资助金额:
$ 92.8万 - 项目类别:
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