Research Services Core

项目摘要-研究服务核心。密西西比临床和医学中心的目标是 转化研究（MCCTR）研究服务核心（RSC）是培训和协助研究人员进行研究 制定和实施，包括监管管理、负责任的研究、有效的 招聘和保留，以及研究合规性。RSC将提供广泛的临床， 流行病学和人口健康专业知识，从MCCTR临床和转化研究人员 研究学者（CTRS）计划和试点项目计划（PPP），以促进临床和 翻译（C/T）和人口健康研究，重点是：种族/民族健康差异，农村 保健和远程保健。为了促进C/T研究的实施，以改善密西西比人的生活， RSC将开发一个新的远程保健子核心，以覆盖该州的农村地区，这些地区的 心脏代谢疾病和更差的健康结果。与社区参与和 外联（首席执行官）核心，RSC还将利用新的国家网络，包括密西西比州国务院 卫生部和密西西比州推广服务部的合作，以扩大这些重要临床项目的覆盖范围。 在MCCTR第二阶段，RSC将通过更大的合作伙伴机构扩大电子健康数据的使用。 使用UMMC研究数据仓库和患者队列浏览器，这将允许研究者使用 “真实的世界”的数据来探索各种健康指标和结果。RSC还将促进更广泛的早期 职业调查员参与大型流行病学研究，包括杰克逊心脏研究， 社区动脉粥样硬化风险（ARIC）研究和农村地区纵向风险（RURAL） 通过创建新的队列研究导航员职位进行研究。RSC将与所有核心密切合作， 但与每个MCCTR的生物统计学、流行病学和研究设计（BERD）核心的早期互动 调查人员将尽可能增加项目设计和完成成功机会。UMMC将作为“枢纽”， 临床试验，RSC将通过RSC扩大UMMC临床研究和试验部门的使用 临床研究协调员。RSC将简化MCCTR研究者的临床试验流程， 协助伙伴机构招募和留住不同的参与者。 RSC还将帮助扩大MCCTR合作机构以及其他机构之间的合作 CTR/CTSA，包括马约诊所临床和转化科学中心（CCaTS）、 亚拉巴马伯明翰临床和转化科学中心（UAB CCTS）、路易斯安那临床和 转化科学（LACaTS）和西北大学临床和转化科学研究所 （NUCATS）。这些合作网络将为更大规模的调查提供独特的机会， 健康差距、农村健康和远程保健。

PROJECT SUMMARY-RESEARCH SERVICES CORE. The goal of the Mississippi Center for Clinical and Translational Research (MCCTR) Research Services Core (RSC) is to train and assist investigators in research development and implementation including regulatory management, responsible conduct of research, effective recruitment and retention, and research compliance. The RSC will provide a broad range of clinical, epidemiologic, and population health expertise to investigators from the MCCTR Clinical and Translational Research Scholars (CTRS) Program and Pilot Projects Program (PPP) to facilitate growth in clinical and translational (C/T) and population health research with an emphasis on: racial/ethnic health disparities, rural health, and telehealth. To facilitate implementation of C/T research to improve the lives of Mississippians, the RSC will develop a new Telehealth subcore to reach rural areas of the state, which have high rates of cardiometabolic diseases and worse health outcomes. In collaboration with the Community Engagement and Outreach (CEO) Core, the RSC will also leverage new state networks including the Mississippi State Department of Health and Mississippi State Extension Services to expand the reach of these important clinical programs. During MCCTR Phase II, the RSC will expand use of electronic health data by partner institutions through greater use of the UMMC Research Data Warehouse and Patient Cohort Explorer, which will allow investigators to use “real world” data to explore a variety of health indicators and outcomes. The RSC will also facilitate broader early career investigator involvement in large epidemiologic studies including the Jackson Heart Study, the Atherosclerosis Risk in Communities (ARIC) Study, and the Risk Underlying Rural Areas Longitudinal (RURAL) Study through creation of a new Cohort Study Navigator position. The RSC will work closely with all of the cores but early interactions with the Biostatistics, Epidemiology, and Research Design (BERD) Core with each MCCTR investigator will optimize chances of successful project design and completion. UMMC will serve as the “hub” for clinical trials, and the RSC will expand use of the UMMC Clinical Research and Trials Unit through the RSC Clinical Research Coordinators. The RSC will streamline the clinical trial process for MCCTR investigators and assist with participant recruitment and retention of a diverse participant population by the partner institutions. The RSC will also help expand collaborations between the MCCTR partner institutions as well as other CTRs/CTSAs including the Mayo Clinic Center for Clinical and Translational Science (CCaTS), the University of Alabama Birmingham Center for Clinical and Translational Science (UAB CCTS), the Louisiana Clinical and Translational Science (LACaTS), and the Northwestern University Clinical and Translational Sciences Institute (NUCATS). These collaborative networks will provide unique opportunities for larger scale investigations of health disparities, rural health, and telehealth.