Research Services Core

项目摘要-研究服务核心。密西西比州临床和医疗中心的目标是 翻译研究(MCCTR)研究服务的核心(RSC)是培训和协助研究人员进行研究 开发和实施，包括法规管理、负责任的研究行为、有效 招聘和保留，以及研究合规性。RSC将提供广泛的临床、 向MCCTR临床和翻译中心的研究人员提供流行病学和人口健康方面的专业知识 研究学者(CTRS)计划和试点项目计划(PPP)，以促进临床和 翻译(C/T)和人口健康研究，重点是：种族/民族健康差距，农村 健康和远程医疗。为了促进C/T研究的实施，以改善密西西比州人的生活， RSC将开发一种新的远程医疗亚核心，以覆盖该州的农村地区，这些地区的 心脏代谢性疾病和更糟糕的健康结果。与社区参与和 外展(CEO)核心，RSC还将利用包括密西西比州国务院在内的新的州网络 卫生和密西西比州推广服务部，以扩大这些重要临床项目的覆盖范围。 在MCCTR第二阶段，RSC将通过更多的 使用UMMC研究数据仓库和患者队列浏览器，这将允许调查人员使用 《现实世界》数据探索各种健康指标和结果。RSC还将促进更广泛的早期 职业调查员参与大型流行病学研究，包括杰克逊心脏研究， 社区动脉粥样硬化风险(ARIC)研究和农村地区纵向(农村)潜在风险 通过创建新的队列研究导航员职位进行研究。皇家莎士比亚委员会将与所有核心密切合作 但与每个MCCTR的生物统计学、流行病学和研究设计(BERD)核心的早期互动 调查员将优化成功设计和完成项目的机会。联华电子将成为 临床试验，RSC将通过RSC扩大UMMC临床研究和试验单位的使用 临床研究协调员。RSC将简化MCCTR研究人员的临床试验流程和 协助伙伴机构招募参与者并留住多样化的参与者群体。 RSC还将帮助扩大MCCTR伙伴机构以及其他机构之间的合作 CTRS/CTSA，包括梅奥临床和翻译科学中心(CCATS)，华盛顿大学 阿拉巴马州伯明翰临床和翻译科学中心(UAB CCTS)，路易斯安那州临床和翻译科学中心 翻译科学(LACATS)和西北大学临床与翻译科学研究所 (NUCATS)。这些合作网络将为更大规模的调查提供独特的机会 健康差距、农村健康和远程医疗。

PROJECT SUMMARY-RESEARCH SERVICES CORE. The goal of the Mississippi Center for Clinical and Translational Research (MCCTR) Research Services Core (RSC) is to train and assist investigators in research development and implementation including regulatory management, responsible conduct of research, effective recruitment and retention, and research compliance. The RSC will provide a broad range of clinical, epidemiologic, and population health expertise to investigators from the MCCTR Clinical and Translational Research Scholars (CTRS) Program and Pilot Projects Program (PPP) to facilitate growth in clinical and translational (C/T) and population health research with an emphasis on: racial/ethnic health disparities, rural health, and telehealth. To facilitate implementation of C/T research to improve the lives of Mississippians, the RSC will develop a new Telehealth subcore to reach rural areas of the state, which have high rates of cardiometabolic diseases and worse health outcomes. In collaboration with the Community Engagement and Outreach (CEO) Core, the RSC will also leverage new state networks including the Mississippi State Department of Health and Mississippi State Extension Services to expand the reach of these important clinical programs. During MCCTR Phase II, the RSC will expand use of electronic health data by partner institutions through greater use of the UMMC Research Data Warehouse and Patient Cohort Explorer, which will allow investigators to use “real world” data to explore a variety of health indicators and outcomes. The RSC will also facilitate broader early career investigator involvement in large epidemiologic studies including the Jackson Heart Study, the Atherosclerosis Risk in Communities (ARIC) Study, and the Risk Underlying Rural Areas Longitudinal (RURAL) Study through creation of a new Cohort Study Navigator position. The RSC will work closely with all of the cores but early interactions with the Biostatistics, Epidemiology, and Research Design (BERD) Core with each MCCTR investigator will optimize chances of successful project design and completion. UMMC will serve as the “hub” for clinical trials, and the RSC will expand use of the UMMC Clinical Research and Trials Unit through the RSC Clinical Research Coordinators. The RSC will streamline the clinical trial process for MCCTR investigators and assist with participant recruitment and retention of a diverse participant population by the partner institutions. The RSC will also help expand collaborations between the MCCTR partner institutions as well as other CTRs/CTSAs including the Mayo Clinic Center for Clinical and Translational Science (CCaTS), the University of Alabama Birmingham Center for Clinical and Translational Science (UAB CCTS), the Louisiana Clinical and Translational Science (LACaTS), and the Northwestern University Clinical and Translational Sciences Institute (NUCATS). These collaborative networks will provide unique opportunities for larger scale investigations of health disparities, rural health, and telehealth.