Cardiovascular Outcomes Research in Perioperative Medicine - COR-PM

围手术期医学心血管结局研究 - COR-PM

• 批准号: 10392118
• 负责人: Karsten Bartels
• 金额: $ 1万
• 依托单位: UNIVERSITY OF NEBRASKA MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-11-23 至 2022-10-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10392118
• 关键词: Address; Advisory Committees; African; Anesthesiology; Anesthetics; Applications Grants; Area; Atmosphere; Benchmarking; Cardiology; Cardiovascular Surgical Procedures; Cardiovascular system; Career Mobility; Cessation of life; Clinical; Clinical Research; Diagnosis; Effectiveness; Ensure; Event; Expenditure; Funding; Goals; Grant Review; Heart; Home; Hospitals; Human; Institution; International; Knowledge; Lead; Location; Medicine; Mentors; Mentorship; Methods; Modality; Modeling; Operative Surgical Procedures; Organ; Outcome; Outcomes Research; Participant; Patients; Perioperative; Perioperative Care; Peripheral; Physicians; Prevention; Productivity; Professional Organizations; Quality of Care; Recommendation; Research; Research Methodology; Research Personnel; Resources; Scholarship; Scientist; Secondary to; Societies; Surveys; Translating; Underrepresented Populations; United States; United States National Institutes of Health; Woman; base; career development; catalyst; design; disability; innovation; inpatient surgery; meetings; member; mortality; novel; patient safety; perioperative mortality; recruit; satisfaction; success; symposium; translational pipeline; virtual; working group

Abstract Anesthesiology research has contributed to dramatic improvements in patient safety and quality of care. Although in the United States, only 8.2 deaths per million surgical hospital discharges are secondary to apparent anesthetic complications, 30-day mortality after inpatient surgeries still ranges at 1.3%. The most common and potentially preventable causes of 30-day mortality after non-cardiac surgery are cardiovascular events. With more than 300 million patients having surgeries worldwide, the potential of improvements in perioperative care to reduce human suffering and harm is immense. Despite its relevance to perioperative mortality, high-quality clinical cardiovascular outcomes research, in particular, is not commonly conducted in the majority of US academic anesthesiology departments. Indeed, the ongoing decline in the physician-scientist workforce sparked the Director of NIH, Dr. Francis Collins, to convene the physician-scientist working group to provide recommendations to enhance its robustness and diversity. The field of anesthesiology lags behind in NIH funding, e.g., as compared to surgery or medicine departments. Yet, despite efforts to provide junior applicants with a competitive advantage, the critical transition from career development to independent investigator status, often referred to as “K2R”, remains a significant challenge, especially for women and investigators from underrepresented in medicine backgrounds. Currently, the typical model for a mentor/mentee relationship is conditional on physical proximity. COR-PM challenges this status quo, by proposing mentees from around the US to lead a cross-institutional mentoring effort, that will be independent of the physical location of mentee and mentor. To achieve the conference’s objectives, the investigators have designed a steering group comprised of 25 junior investigators from across the US, advised by an international eight-member senior advisory panel comprised of independent investigators with a track record of success in clinical cardiovascular outcomes research. Using a “By Mentees – With Mentors – For Mentees” paradigm, the investigators propos three specific aims. Aim 1: Organize the 2022 Cardiovascular Outcomes Research in Perioperative Medicine - COR-PM to advance clinical outcomes research in cardiovascular medicine within the T2-T4 translational spectrum. Aim 2: Provide mentorship capacity for junior investigators by providing tangible mentoring to attendees through pairing mentees with mentors across institutions. Aim 3: Create an inclusive and welcoming conference atmosphere by enhancing diversity and in all aspects of conference planning and implementation. The expected outcome of this conference is for participants to gain knowledge in the area of perioperative cardiovascular outcomes research and benefit from establishing mentoring relationships outside of their respective home institutions. COR-PM will thereby have an immediate and positive impact.

抽象的 麻醉学研究极大地提高了患者安全和护理质量。 尽管在美国，每百万例外科出院病例中只有 8.2 例死亡是继发性死亡 除了明显的麻醉并发症之外，住院手术后 30 天的死亡率仍为 1.3%。这 非心脏手术后 30 天死亡的最常见且可能可预防的原因是 心血管事件。全球有超过 3 亿患者接受手术， 围手术期护理的改善对减少人类痛苦和伤害是巨大的。尽管其 与围手术期死亡率、高质量临床心血管结局研究的相关性 特别是，在美国大多数学术麻醉科并不普遍进行。 事实上，医师科学家队伍的持续下降引发了美国国立卫生研究院院长弗朗西斯博士的不满。 柯林斯，召集医师科学家工作组，提供建议，以加强其 稳健性和多样性。麻醉学领域在 NIH 资金方面落后，例如，与 外科或内科部门。然而，尽管努力为初级申请者提供有竞争力的机会 优势，从职业发展到独立调查员地位的关键转变，通常 被称为“K2R”，仍然是一个重大挑战，特别是对于女性和来自 医学背景的代表性不足。目前，导师/受训者的典型模型 关系以身体接近为条件。 COR-PM 挑战这一现状，提出 来自美国各地的受训者领导跨机构的指导工作，该工作将独立于 受训者和导师的实际位置。为了实现会议的目标，研究人员 设计了一个由来自美国各地的 25 名初级研究人员组成的指导小组，并由 一个由八名成员组成的国际高级顾问小组，由独立调查员组成 临床心血管结果研究的成功记录。使用“受训者 – 与 “导师 – 对于受训者”范式，研究人员提出了三个具体目标。目标 1：组织 2022 年围手术期医学心血管结果研究 - COR-PM 推进临床 T2-T4 转化谱范围内心血管医学的结果研究。目标 2：提供 通过向与会者提供切实的指导来提高初级研究者的指导能力 将受训者与跨机构的导师配对。目标 3：创建一个包容、热情的会议 通过增强会议规划和实施各个方面的多样性来营造良好的氛围。这 本次会议的预期成果是让与会者获得围手术期领域的知识 心血管结果研究并从在其外部建立指导关系中受益 各自的家乡机构。因此，COR-PM 将产生立竿见影的积极影响。