Cardiovascular Outcomes Research in Perioperative Medicine - COR-PM

围手术期医学心血管结局研究 - COR-PM

• 批准号: 10392118
• 负责人: Karsten Bartels
• 金额: $ 1万
• 依托单位: UNIVERSITY OF NEBRASKA MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-11-23 至 2022-10-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10392118
• 关键词: Address; Advisory Committees; African; Anesthesiology; Anesthetics; Applications Grants; Area; Atmosphere; Benchmarking; Cardiology; Cardiovascular Surgical Procedures; Cardiovascular system; Career Mobility; Cessation of life; Clinical; Clinical Research; Diagnosis; Effectiveness; Ensure; Event; Expenditure; Funding; Goals; Grant Review; Heart; Home; Hospitals; Human; Institution; International; Knowledge; Lead; Location; Medicine; Mentors; Mentorship; Methods; Modality; Modeling; Operative Surgical Procedures; Organ; Outcome; Outcomes Research; Participant; Patients; Perioperative; Perioperative Care; Peripheral; Physicians; Prevention; Productivity; Professional Organizations; Quality of Care; Recommendation; Research; Research Methodology; Research Personnel; Resources; Scholarship; Scientist; Secondary to; Societies; Surveys; Translating; Underrepresented Populations; United States; United States National Institutes of Health; Woman; base; career development; catalyst; design; disability; innovation; inpatient surgery; meetings; member; mortality; novel; patient safety; perioperative mortality; recruit; satisfaction; success; symposium; translational pipeline; virtual; working group

Abstract Anesthesiology research has contributed to dramatic improvements in patient safety and quality of care. Although in the United States, only 8.2 deaths per million surgical hospital discharges are secondary to apparent anesthetic complications, 30-day mortality after inpatient surgeries still ranges at 1.3%. The most common and potentially preventable causes of 30-day mortality after non-cardiac surgery are cardiovascular events. With more than 300 million patients having surgeries worldwide, the potential of improvements in perioperative care to reduce human suffering and harm is immense. Despite its relevance to perioperative mortality, high-quality clinical cardiovascular outcomes research, in particular, is not commonly conducted in the majority of US academic anesthesiology departments. Indeed, the ongoing decline in the physician-scientist workforce sparked the Director of NIH, Dr. Francis Collins, to convene the physician-scientist working group to provide recommendations to enhance its robustness and diversity. The field of anesthesiology lags behind in NIH funding, e.g., as compared to surgery or medicine departments. Yet, despite efforts to provide junior applicants with a competitive advantage, the critical transition from career development to independent investigator status, often referred to as “K2R”, remains a significant challenge, especially for women and investigators from underrepresented in medicine backgrounds. Currently, the typical model for a mentor/mentee relationship is conditional on physical proximity. COR-PM challenges this status quo, by proposing mentees from around the US to lead a cross-institutional mentoring effort, that will be independent of the physical location of mentee and mentor. To achieve the conference’s objectives, the investigators have designed a steering group comprised of 25 junior investigators from across the US, advised by an international eight-member senior advisory panel comprised of independent investigators with a track record of success in clinical cardiovascular outcomes research. Using a “By Mentees – With Mentors – For Mentees” paradigm, the investigators propos three specific aims. Aim 1: Organize the 2022 Cardiovascular Outcomes Research in Perioperative Medicine - COR-PM to advance clinical outcomes research in cardiovascular medicine within the T2-T4 translational spectrum. Aim 2: Provide mentorship capacity for junior investigators by providing tangible mentoring to attendees through pairing mentees with mentors across institutions. Aim 3: Create an inclusive and welcoming conference atmosphere by enhancing diversity and in all aspects of conference planning and implementation. The expected outcome of this conference is for participants to gain knowledge in the area of perioperative cardiovascular outcomes research and benefit from establishing mentoring relationships outside of their respective home institutions. COR-PM will thereby have an immediate and positive impact.

摘要 麻醉学研究极大地提高了患者的安全性和护理质量。 尽管在美国，每百万个外科医院出院只有8.2人死亡，是次要的 对于明显的麻醉并发症，住院手术后30天的死亡率仍在1.3%。这个 非心脏手术后30天死亡的最常见和可能预防的原因是 心血管事件。全球有超过3亿患者接受手术，潜在的 改善围手术期护理以减少人类的痛苦和伤害是巨大的。尽管它的 与围手术期死亡率的相关性，高质量的临床心血管结果研究 特别是，在美国大多数学术麻醉科并不普遍进行。 事实上，医生-科学家队伍的持续下降促使美国国立卫生研究院院长弗朗西斯博士 Collins，召集医生-科学家工作组提出建议，以加强其 稳健性和多样性。麻醉学领域在NIH资金方面落后，例如，与 外科或内科。然而，尽管努力为初级申请者提供具有竞争力的 优势，从职业发展到独立调查员地位的关键过渡，通常 被称为“K2R”，仍然是一个重大挑战，特别是对妇女和来自 在医学背景中代表性不足。目前，导师/学员的典型模式 关系是以身体上的亲近为条件的。COR-PM挑战这一现状，提出 来自美国各地的受训者领导一个跨机构的指导工作，这将独立于 被辅导者和辅导者的实际位置。为了实现会议的目标，调查人员 我设计了一个由来自美国各地的25名初级调查人员组成的指导小组，建议 一个由八人组成的国际高级咨询小组，由独立调查人员组成 在临床心血管结果研究方面取得成功的记录。使用“由被辅导者-与” 导师-对于被导师的范式，调查人员提出了三个具体目标。目标1：组织 2022年围术期心血管结局研究--COR-PM推进临床 T2-T4翻译谱内心血管医学的结果研究。目标2：提供 初级调查人员的指导能力，通过以下方式为与会者提供有形的指导 将学员与不同机构的导师配对。目标3：创造一个包容和欢迎的会议 通过加强多样性以及在会议规划和执行的所有方面营造氛围。这个 本次会议的预期结果是让与会者获得围手术期的知识。 心血管结果研究并受益于在其外部建立指导关系 各自的本土机构。COR-PM因此将产生立竿见影的积极影响。