Initiative to Maximize Research Education in Genomics: Diversity Action Plan (DAP)

最大化基因组学研究教育的倡议：多样性行动计划（DAP）

• 批准号: 10631939
• 负责人: RICHARD A GIBBS
• 金额: $ 29.97万
• 依托单位: BAYLOR COLLEGE OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-08-19 至 2024-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10631939
• 关键词: Address; African American; African American population; African American student; Area; Atmosphere; Award; Bachelor' s Degree; Behavioral Research; Bioinformatics; Biological Sciences; Biomedical Research; Clinical Research; Competence; Country; Critical Thinking; Data; Disparity; Doctor of Philosophy; Doctor' s Degree; Education; Educational Activities; Educational Curriculum; Engineering; Faculty; Foundations; Funding; Genetic; Genetic Variation; Genomics; Goals; Graduate Education; Health; Hispanic Populations; Human; Human Genetics; Human Genome Project; Institution; Internships; Intervention; Journals; Knowledge; Lead; Medicine; Minority; Minority Groups; Molecular Genetics; National Human Genome Research Institute; Native Americans; Outcome; Postbaccalaureate; Recording of previous events; Research; Research Training; STEM career; STEM field; Science; Science, Technology, Engineering and Mathematics; Scientist; Students; Training; Training Activity; Training Programs; Training and Education; Underrepresented Populations; Underrepresented Students; United States; Visit; career; college; education research; educational atmosphere; experience; graduate school; graduate student; human disease; human genome sequencing; improved; innovation; interest; intervention program; next generation; pre-doctoral; prevent; programs; recruit; skills; student participation; student retention; success; successful intervention; summer internship; summer research; summer student; therapy development; undergraduate student

Project Summary/Abstract The United States (US) science, technology, engineering, and mathematics (STEM) workforce has been a world leader in biomedical research for decades, and in the 21st century the US took the lead in sequencing the human genome. The STEM workforce has also faced the challenge of increasing participation of under-represented (UR) populations to remain competitive in science and engineering. The National Human Genome Research Institute (NHGRI) had the foresight from the outset of the Human Genome Project to include training (Diversity Action Plan-DAP) that would address this shortage as the field developed. In spite of many national interventions, several minority groups remain underrepresented at all degree and professional career levels.1-2 For example, of the 76,447 doctorate degrees awarded in the biological sciences in 2012, only 3,677 (4.8%) were African Americans, 4,463 (5.8%) were Hispanics, and 314 (0.41%) were Native Americans. 1 Therefore, the development of intervention programs seeking to ameliorate these disparities within science research become important and necessary. The long term goal of this proposal is to increase UR PhDs in genomics and bioinformatics. We will approach this goal in two specific aims. Aim 1 will provide six undergraduate and 8 post-baccalaureate students DI training activities that result in 75% completing the program with greater genomics/bioinformatics knowledge and lab-based critical thinking skills appropriate for success in graduate school. Although the number of UR PhDs is low in biomedical research, in the field of bioinformatics there is a shortage of US trained scientists in this area and the UR groups are even more severely limited in this new field. Aim 2 plans to recruit and retain 50% of DI trainees as graduate students in the Molecular and Human Genetics Department at Baylor College of Medicine. The African American applicant pool is lowest among all under-represented groups that apply to the MHG department. We will address these aims, using research training as our foundation, in the HGSC-DI summer research internship and Post-baccalaureate programs. Our program data indicates the following DI results: 72% of our post-baccalaureate students enter PhD programs; 100% of pre-doctoral alumni are retained in PhD programs; and 100% of the summer interns obtain bachelor's degrees. We have proven ability to recruit and retain students in STEM. The overall impact of this proposal will increase the number of UR PhDs in genomics and trained in bioinformatics.

项目总结/摘要 美国（US）科学、技术、工程和数学（STEM）劳动力一直在 几十年来一直是生物医学研究的世界领导者，而在21世纪，美国在生物医学研究方面处于领先地位 对人类基因组进行测序。STEM劳动力也面临着增加 代表性不足（UR）人口的参与，以保持在科学和工程方面的竞争力。的 国家人类基因组研究所（NHGRI）从人类基因组研究开始就有远见。 基因组项目包括培训（多样性行动计划-DAP），以解决这一短缺， 场开发。尽管国家采取了许多干预措施，但若干少数群体的代表性仍然不足 1 -2例如，在1998年颁发的76，447个博士学位中， 在2012年的生物科学中，只有3,677人（4.8%）是非洲裔美国人，4,463人（5.8%）是西班牙裔， 314人（0.41%）为美洲原住民。1、制定干预方案 在科学研究中寻求改善这些差距变得重要和必要。 该提案的长期目标是增加UR基因组学和生物信息学博士学位。我们将 在两个具体目标中实现这一目标。目标1将提供6个本科和8个学士后学位 学生DI培训活动，导致75%的完成计划， 基因组学/生物信息学知识和基于实验室的批判性思维技能，适合在 研究生院虽然UR博士的数量在生物医学研究中很低，但在生物医学领域， 生物信息学在这一领域缺乏美国训练有素的科学家，而UR小组甚至更多。 在这一新领域受到严重限制。目标2计划招收并保留50%的DI学员作为研究生 贝勒医学院分子和人类遗传学系的教授。非裔美国人 在申请MHG部门的所有代表性不足的群体中，申请人人数最少。我们将 在HGSC-DI夏季研究中，以研究培训为基础，实现这些目标 实习和学士后课程。我们的程序数据表明以下DI结果： 我们的学士后学生进入博士课程; 100%的博士前校友被保留在 博士课程;和100%的暑期实习生获得学士学位。我们有能力证明 招募和留住STEM学生。这一建议的总体影响将增加工发组织代表的数目， 基因组学博士和生物信息学培训。