Bioinformatics Core

最具影响力的核心是与用户一起预测、适应和发展的核心。风景名胜 自MT INBRE计划开始以来，生物信息学已经有了显著的发展。因此，MT INBRE IV具有进化的生物信息学和生物统计核心(BBC)，经过优化以满足 蒙大拿州和地区合作伙伴的新一代研究人员。英国广播公司在MT INBRE I-III的开发是为了 满足执行基因组学、元基因组学、转录组学和相关的高质量基因组学研究人员的需求 这些技术所需的吞吐量数据分析。这些“组学”方法现在对许多人来说是必不可少的 以实验室为基础的生物研究和公共卫生项目。作为回应，英国广播公司发展成为 是蒙大拿州研究和教学不可或缺的组成部分。适用于MT INBRE III网络 调查人员，BBC提供了高性能的研究计算、专业知识和培训 使用生物信息学软件，并提供生物统计学支持。此外，英国广播公司还为学生提供了 生物信息学和开发专门的数据分析管道。就这样，核心服务于MT INBRE III的科学界和蒙大拿州更大的生物医学研究界。这也是有帮助的 教育将进入生物统计学和生物信息学职业生涯的学生和/或继续应用高级 为他们的研究项目提供工具。在MT INBRE IV中，BBC将建立在 MT INBRE I-III，加强和增加支持我们客户的活动和服务。在MT INBRE期间 生物信息学学院咨询委员会，所有核心主任，以及MT INBRE PI和PC分析 整个网络中MT INBRE调查人员和学生的当前和未来需求，纳入了意见 来自MT INBRE III外部咨询委员会制定加强核心的目标。要实现这些目标 目标，我们将实现三个具体目标。目标1：维护和进一步发展MT INBRE IV 生物信息学和生物统计学核心(BBC)领导团队和整体能力，以支持和提高 基础和临床科学的未来研究方向。目标2：继续提供培训机会 支持网络研究人员的研究，并让学生接触到不断扩大的多元组学领域。目标3： 提高MT INBRE IV网络和RAIN的生物医学研究能力 支持重点领域研究的资源和设施。

The most impactful core is one that anticipates, adapts, and develops with its users. The landscape of bioinformatics has expanded significantly since the beginning of the MT INBRE program. Therefore, MT INBRE IV features an evolved Bioinformatics and Biostatistics Core (BBC) optimized to meet the needs of a new breed of researchers across Montana and regional partners. The BBC in MT INBRE I-III was developed to meet the needs of investigators performing genomics, metagenomics, transcriptomics and the associated high- throughput data analysis needed for these techniques. These “omics” approaches are now essential to many laboratory-based biological research and public health projects as well. In response, the BBC developed into an integral and essential component of research and teaching in Montana. For MT INBRE III network investigators, the BBC provided access to high performance research computing, expertise and training on the use of bioinformatics software, and biostatistical support. In addition, the BBC provided training for students in bioinformatics and the development of specialized data analysis pipelines. In this way, the Core served MT INBRE III's scientific community and the greater biomedical research community in Montana. It also helped educate students who will enter careers in biostatistics and bioinformatics and/or continue to apply advanced tools to their research programs. In MT INBRE IV, the BBC will build upon the solid foundation established in MT INBRE I-III, enhancing and adding to the activities and services supporting our clients. During MT INBRE III, the bioinformatics Faculty Advisory Committee, all Core Directors, and the MT INBRE PI and PC analyzed the current and future needs of MT INBRE investigators and students across the network, incorporating input from the MT INBRE III External Advisory Committee to develop goals for enhancing the core. To achieve these goals, we will accomplish three specific aims. Aim 1: Maintain and further develop the MT INBRE IV Bioinformatics and Biostatistics Core (BBC) Leadership Team and overall capacity to support and enhance future research directions in basic and clinical science. Aim 2: Continue to provide training opportunities to support Network investigators' research and expose students to the expanding field of multi-omics. Aim 3: Increase biomedical research capacity across the MT INBRE IV Network and RAIN by providing enhanced resources and facilities to support research in focus areas.