Bioinformatics Core

生物信息学核心

• 批准号: 10631973
• 负责人: Jeffrey Good
• 金额: $ 40.74万
• 依托单位: MONTANA STATE UNIVERSITY - BOZEMAN
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-09-25 至 2024-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10631973
• 关键词: Advisory Committees; American Indians; Area; Basic Science; Bioinformatics; Biomedical Research; Biometry; Biostatistics Core; Breeding; Centers of Research Excellence; Client; Clinical Sciences; Collaborations; Communities; Computer software; Data Analyses; Data Collection; Development; Doctor of Philosophy; Ecology; Educational process of instructing; Educational workshop; Environment; Faculty; Foundations; Future; Genomics; Goals; Grant; Human; Institutionalization; Interdisciplinary Study; Laboratories; Leadership; Learning; Mass Spectrum Analysis; Mentors; Metagenomics; Montana; Performance; Positioning Attribute; Preparation; Problem Solving; Proteomics; Public Health; Research; Research Assistant; Research Personnel; Research Project Grants; Research Support; Resources; Rural health equity; Sampling; Services; Solid; Students; Systems Biology; Techniques; Testing; Training; Universities; Work; bioinformatics tool; biological research; career; data analysis pipeline; gateway course; graduate student; metabolomics; multiple omics; outreach; programs; response; social; student training; support network; tool; training opportunity; transcriptomics; tribal college; working group

The most impactful core is one that anticipates, adapts, and develops with its users. The landscape of bioinformatics has expanded significantly since the beginning of the MT INBRE program. Therefore, MT INBRE IV features an evolved Bioinformatics and Biostatistics Core (BBC) optimized to meet the needs of a new breed of researchers across Montana and regional partners. The BBC in MT INBRE I-III was developed to meet the needs of investigators performing genomics, metagenomics, transcriptomics and the associated high- throughput data analysis needed for these techniques. These “omics” approaches are now essential to many laboratory-based biological research and public health projects as well. In response, the BBC developed into an integral and essential component of research and teaching in Montana. For MT INBRE III network investigators, the BBC provided access to high performance research computing, expertise and training on the use of bioinformatics software, and biostatistical support. In addition, the BBC provided training for students in bioinformatics and the development of specialized data analysis pipelines. In this way, the Core served MT INBRE III's scientific community and the greater biomedical research community in Montana. It also helped educate students who will enter careers in biostatistics and bioinformatics and/or continue to apply advanced tools to their research programs. In MT INBRE IV, the BBC will build upon the solid foundation established in MT INBRE I-III, enhancing and adding to the activities and services supporting our clients. During MT INBRE III, the bioinformatics Faculty Advisory Committee, all Core Directors, and the MT INBRE PI and PC analyzed the current and future needs of MT INBRE investigators and students across the network, incorporating input from the MT INBRE III External Advisory Committee to develop goals for enhancing the core. To achieve these goals, we will accomplish three specific aims. Aim 1: Maintain and further develop the MT INBRE IV Bioinformatics and Biostatistics Core (BBC) Leadership Team and overall capacity to support and enhance future research directions in basic and clinical science. Aim 2: Continue to provide training opportunities to support Network investigators' research and expose students to the expanding field of multi-omics. Aim 3: Increase biomedical research capacity across the MT INBRE IV Network and RAIN by providing enhanced resources and facilities to support research in focus areas.

最有影响力的核心是预测，适应和与用户一起发展。的景观 自MT INBRE计划开始以来，生物信息学已经显著扩展。因此，MT INBRE IV具有经过优化的生物信息学和生物统计学核心（BBC），以满足 蒙大拿州和地区合作伙伴的新一代研究人员。MT INBRE I-III中的BBC被开发为 满足研究人员进行基因组学，宏基因组学，转录组学和相关的高， 这些技术所需的吞吐量数据分析。这些“组学”方法现在对许多人来说至关重要， 以实验室为基础的生物研究和公共卫生项目。作为回应，BBC发展成为 研究和教学在蒙大拿州的一个组成部分和重要组成部分。用于MT INBRE III网络 调查人员，英国广播公司提供了高性能的研究计算，专业知识和培训， 使用生物信息学软件和生物统计学支持。此外，英国广播公司还为学生提供培训， 生物信息学和开发专门的数据分析管道。这样，Core服务于MT INBRE III的科学界和蒙大拿州更大的生物医学研究界。它还帮助 教育学生谁将进入职业生涯在生物统计学和生物信息学和/或继续应用先进的 他们的研究计划的工具。在MT INBRE IV中，BBC将建立在 MT INBRE I-III，增强和增加支持客户的活动和服务。MT INBRE期间 三、生物信息学系咨询委员会、所有核心主任以及MT INBRE PI和PC分析 MT INBRE研究人员和学生在整个网络中的当前和未来需求， 来自MT INBRE III外部咨询委员会的建议，以制定加强核心的目标。实现这些 目标，我们将实现三个具体目标。目标1：维持和进一步发展MT INBRE IV 生物信息学和生物统计学核心（BBC）领导团队和整体能力，以支持和提高 基础和临床科学的未来研究方向。目标2：继续提供培训机会， 支持网络调查人员的研究，并让学生接触到不断扩大的多组学领域。目标三： 通过提供增强的生物医学研究能力，提高MT INBRE IV网络和RAIN的生物医学研究能力 资源和设施，以支持重点领域的研究。