Histology and Imaging Core
组织学和成像核心
基本信息
- 批准号:10414548
- 负责人:
- 金额:$ 26.03万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2022
- 资助国家:美国
- 起止时间:2022-06-01 至 2027-05-31
- 项目状态:未结题
- 来源:
- 关键词:AcademiaAdvisory CommitteesAntibodiesApplications GrantsAwardBiologicalBiomedical ResearchBrainBusinessesCaliberCaringCenters of Research ExcellenceCollaborationsCommunicationCommunitiesComputer softwareContract ServicesContractsDataDensitometryDevelopmentEnsureEquipmentEvaluationExtramural ActivitiesFacultyFee-for-Service PlansFeedbackFeesFluorescenceFreezingFundingGoalsGrantHistologicHistologyHuman ResourcesImageImage AnalysisImmunohistochemistryIncomeIndustryInstitutesInstitutionInvestmentsLaboratoriesLaboratory PersonnelMaineMaintenanceMedical centerMethodsMicroscopeMicrotome - medical deviceNew EnglandPainParaffin EmbeddingPerformancePhasePlastic EmbeddingProceduresProviderPublicationsReproducibilityResearchResearch InstituteResearch MethodologyResearch PersonnelResearch Project GrantsResearch SupportResourcesRoleSamplingScanningSecureSensoryService delivery modelServicesSlideStainsStrategic PlanningStreamStudentsSystemTechnical ExpertiseTimeTissue EmbeddingTrainingUnited States National Institutes of HealthUniversitiesValidationWagesWorkbasebonecryostatexperienceexperimental studyimaging capabilitiesindustry partnerinstrumentationoutreachprogramsquantitative imagingresearch facilitysuccesssynergismtwo photon microscopytwo-photonvoucher
项目摘要
Prior to the initiation of this COBRE, there were no research cores at the University of New England (UNE). Phase 1 and
2 COBRE support resulted in the development of the Histology and Imaging Core (HIC) into a critical resource for
COBRE investigators and the broader research community at UNE and the region. The Core's histology instrumentation
includes tissue embedding equipment, microtomes, vibratomes, cryostats and slide staining workstations. Imaging
equipment includes brightfield, widefield fluorescence, slide-scanning, confocal and 2-photon microscopes. Technical
services include tissue embedding, sectioning, conventional histology stains, immunohistochemistry, and antibody
optimization and validation. In Phase 2, the HIC provided services to 38 investigators (15 UNE-COBRE, 8 UNE-non-
COBRE, 10 in external academia and 5 in industry), and trained 175 laboratory personnel. Also in Phase 2, a fee-for-
service model was initiated, and strong partnerships with other IDeA institutions at Brown University and Maine Medical
Center Research Institute were developed that, in combination with internal users, have the potential to be long-term
sustaining providers of Core income. Special care has been taken to ensure that the Core capabilities do not duplicate
those offered by other COBRE- and INBRE-supported research cores. Instead, the Core has strategically specialized in
unique services such the processing of brain samples, bone samples and marine-derived samples. In Phase 3, the HIC will
maintain its current outstanding level of performance, critically assess its performance, continue to develop its personnel
professionally, and hire an additional technician to keep pace with the needs of its broadening user base. The HIC will
also undertake a rigorous strategic planning program under the direction of a UNE expert in small business strategy, with
the goal of completing its transition to post-award sustainability. The HIC has secured critical additional institutional
support, including guarantees of post-Phase 3 salary for key Core personnel, protected time for Directors, laboratory
space, assistance with maintenance and service contracts, and an internally funded core voucher program and continuation
of the UNE mini-grant program for those striving for extramural support. Through these efforts, the UNE HIC will
continue to provide excellent critical research support to its many users, ensuring maximum utility to UNE and the
broader research community in Phase 3 and beyond.
在此COBRE启动之前,新英格兰大学(UNE)没有研究核心。第一阶段及
项目成果
期刊论文数量(0)
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{{ truncateString('DEREK C MOLLIVER', 18)}}的其他基金
Mitochondrial regulation of nociceptor function
伤害感受器功能的线粒体调节
- 批准号:
10644865 - 财政年份:2023
- 资助金额:
$ 26.03万 - 项目类别:
Adenylyl cyclase signaling in persistent pain
持续性疼痛中的腺苷酸环化酶信号传导
- 批准号:
10418657 - 财政年份:2019
- 资助金额:
$ 26.03万 - 项目类别:
Purinergic G protein signal integration in nociceptors
伤害感受器中的嘌呤能 G 蛋白信号整合
- 批准号:
9049508 - 财政年份:2013
- 资助金额:
$ 26.03万 - 项目类别:
Purinergic G protein signal integration in nociceptors
伤害感受器中的嘌呤能 G 蛋白信号整合
- 批准号:
8838952 - 财政年份:2013
- 资助金额:
$ 26.03万 - 项目类别:
Purinergic G protein signal integration in nociceptors
伤害感受器中的嘌呤能 G 蛋白信号整合
- 批准号:
8500600 - 财政年份:2013
- 资助金额:
$ 26.03万 - 项目类别:
Pro- and Anti-Nociceptive Actions of P2y Nucleotide Receptors in Sensory Neurons
感觉神经元中 P2y 核苷酸受体的促伤害和抗伤害作用
- 批准号:
7501933 - 财政年份:2007
- 资助金额:
$ 26.03万 - 项目类别:
Pro- and Anti-Nociceptive Actions of P2y Nucleotide Receptors in Sensory Neurons
感觉神经元中 P2y 核苷酸受体的促伤害和抗伤害作用
- 批准号:
7371619 - 财政年份:2007
- 资助金额:
$ 26.03万 - 项目类别:
Pro- and Anti-Nociceptive Actions of P2y Nucleotide Receptors in Sensory Neurons
感觉神经元中 P2y 核苷酸受体的促伤害和抗伤害作用
- 批准号:
7878610 - 财政年份:2007
- 资助金额:
$ 26.03万 - 项目类别:
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