Short Course on the Genetics of Addiction

成瘾遗传学短期课程

• 批准号: 10652414
• 负责人: Elissa J Chesler
• 金额: $ 2.5万
• 依托单位: JACKSON LABORATORY
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-07-01 至 2025-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10652414
• 关键词: Acceleration; Active Learning; Animal Model; Applied Genetics; Appointment; Atmosphere; Awareness; Behavior; Bioinformatics; Biological; Biology; Brain Diseases; Chronic; Communities; Computer software; Data Analyses; Data Set; Development; Drug Addiction; Educational workshop; Enrollment; Epigenetic Process; Faculty; Food; Fostering; Funding Opportunities; Genetic; Genetic Models; Genetic study; Genomic approach; Genomics; Hand; Heritability; Human; Human Genetics; Institution; Instruction; Laboratories; Learning; Literature; Maine; Methodology; Methods; Modernization; Mus; Participant; Phenotype; Predisposition; Public Health; Reproducibility; Research; Research Personnel; Resources; Role; Scientist; Structure; Students; The Jackson Laboratory; Therapeutic; Time; Training; Translational Research; Underrepresented Minority; Woman; Work; addiction; behavioral phenotyping; career; career development; data resource; design; efficacious treatment; faculty-student interactions; genetic analysis; genetic approach; genetic resource; genome resource; human model; lectures; member; model organism; mouse model; new technology; skills; societal costs; success; symposium; tool

ABSTRACT The annual Short Course on the Genetics of Addiction proposed in this application builds on the successes of the previous iteration of this Course and will provide students with an opportunity to learn about genetic applications and approaches to drug addiction research in humans and model organisms. The methodological instruction includes examples, literature and data sets drawn from studies of addiction-related phenotypes, plenary sessions on major progress in addiction genetics, and discussion sessions in which students each present their work on applications of genetic methods, and discuss general questions provoked by the lectures. Students will leave the course able to design and interpret genetic and genomic studies of addiction as they relate to their specific research question, to locate the opportunities and resources for extrapolation between human genetics and model organisms, and to utilize current online data resources to support their research. These aims will be accomplished annually over the next five years through an intensive five-day course to be offered in late summer at the Jackson Laboratory (JAX) in Bar Harbor, Maine. In 2020, the course will be held September 20-26, with arrivals and a reception on September 20 and departures on September 26. Participants will be chosen for their outstanding research potential in fields relevant to the course and will have the opportunity to interact with a group of prominent computational biologists, bioinformaticists, biologists, and geneticists from JAX and other institutions. A combination of didactic sessions and hands-on training will be offered during the day and informal discussions will be held in the evening. Student enrollment is deliberately kept small (35) to achieve a desirable level of student-faculty interaction. Food and lodging will be provided at the JAX-owned Highseas Conference Center, which creates an atmosphere highly conducive to interactions between students and faculty. A major emphasis will be placed on attracting promising young investigators to participate in this course and to actively promote the inclusion of women and under-represented minorities in an effort to cultivate diversity in the professoriate.

摘要 本申请中提议的成瘾遗传学年度短期课程是建立在以下方面的成功基础上的： 本课程的前一次迭代，并将为学生提供一个机会，了解遗传 在人类和模式生物中药物成瘾研究的应用和方法。的方法论 教学包括例子，文献和数据集从成瘾相关表型的研究， 关于成瘾遗传学重大进展的全体会议，以及学生们各自参加的讨论会。 介绍他们在遗传学方法应用方面的工作，并讨论讲座引起的一般问题。 学生将离开课程能够设计和解释成瘾的遗传和基因组研究，因为他们 联系到他们的具体研究问题，找到机会和资源之间的推断 人类遗传学和模式生物，并利用目前的在线数据资源，以支持他们的研究。 在今后五年里，每年将通过一个为期五天的强化课程来实现这些目标， 在夏末在缅因州巴尔港的杰克逊实验室（JAX）提供。2020年，该课程将在 9月20日至26日，9月20日抵达和接待，9月26日离开。 参与者将被选为他们在相关领域的杰出研究潜力的课程，并将有 有机会与一群杰出的计算生物学家，生物信息学家，生物学家和 来自JAX和其他机构的遗传学家。将结合教学课程和实践培训， 在白天提供，非正式讨论将在晚上举行。学生入学是故意的 保持小（35），以实现学生与教师互动的理想水平。食物和住宿将在 JAX拥有的公海会议中心，创造了一个非常有利于互动的氛围 学生和教师之间。重点将放在吸引有前途的年轻研究人员， 参加这一课程，并积极促进妇女和代表性不足的少数民族参与， 努力培养教授群体的多样性。