Prevention Epicenters Program: Protecting Patients from Infections, Antibiotic Resistance andOther Adverse Events

自2015年以来，我们一直是预防中心（周期II，RFA-CK-18-001）的成员。我们的核心 该研究小组在卫生保健相关感染和抗生素领域发表了430多篇出版物 被引用超过12，000次的阻力。我们核心项目的领导人已经有超过27个 作为主要研究人员获得了赠款和合同，并在科学专门知识领域发表了350多篇出版物 在RFA。自2015年以来，我们与Epicenter II网站合作发表了53篇论文， 与目前的Epicenter I网站合作发表了35篇文章。我们集团最大的优势之一是我们的 利用我们的经验和专业知识，在现有的合作项目中完成合作项目的能力 Epicenters和其他医疗机构。我们提出创新的核心和合作项目， 对CDC优先领域的可行性和响应性。 我们的核心建议是： 1.急性和慢性呼吸道感染患者中多重耐药鲍曼不动杆菌的全州患病率 长期设施。 2.急性护理中医院发病菌血症和真菌血症监测的使用和可用性评价 设施 3.减少多药耐药微生物在护理之家慢性呼吸机单元的传播 4.评估急性护理环境中MRSA接触预防措施的针对性方法的可行性 5.改善临床医生微生物学测试的解释和在所有医疗保健环境中的使用 我们的合作项目提案包括： 1.与急性护理环境中耳念珠菌传播相关的风险因素（大型项目） 2.呼吸机相关性肺炎的诊断管理：一项随机分组交叉试验， 急诊护理机构中的医嘱审查和实验室报告混合干预（中型项目） 通过这些项目和其他合作项目的发展，我们期待着为以下方面作出贡献： 预防中心计划：保护患者免受感染，抗生素耐药性和其他 不良事件。

We have been a member of the Prevention Epicenters (Cycle II, RFA-CK-18-001) since 2015. Our core investigative group has over 430 publications in the area of healthcare-associated infections and antibiotic resistance which have been cited over 12,000 times. The leaders of our core projects have had more than 27 grants and contracts as principal investigators and have over 350 publications in the scientific expertise areas in the RFA. We have collaborated with the current Epicenter II sites on 53 publications since 2015 and have collaborated with current Epicenter I sites on 35 publications. One of our group’s greatest strengths is our ability to leverage our experience and expertise to complete collaborative projects among the existing Epicenters and other healthcare institutions. We propose core and collaborative projects that are innovative, feasible and responsive to CDC priority areas. Our core proposals are: 1. State-wide prevalence of multi-drug resistant Acinetobacter baumannii in ventilated patients in acute and long-term facilities. 2. Evaluation of use and usability of surveillance for hospital-onset bacteremia and fungemia in acute care facilities 3. Decreasing Transmission of Multi-drug Resistant Organisms in Chronic Ventilator Units in Nursing Homes 4. Assessing feasibility of a targeted approach to contact precautions for MRSA in the acute care setting 5. Improving clinician microbiology test interpretation and use in all healthcare settings Our collaborative project proposals are: 1. Risk factors associated with transmission of Candida auris in the acute care setting (Large Project) 2. Diagnostic Stewardship for Ventilator Associated Pneumonia: A cluster-randomized crossover trial of a hybrid order-review and laboratory reporting intervention in acute care facilities (Medium project) Through these projects and the development of other collaborative projects, we look forward to contributing to the Prevention Epicenters Program: Protecting Patients from Infections, Antibiotic Resistance and Other Adverse Events.