K24 Clinical Research in Antimicrobial Resistance and Hospital Epidemiology

K24 抗菌药物耐药性和医院流行病学临床研究

• 批准号: 8416369
• 负责人: ANTHONY D HARRIS
• 金额: $ 18万
• 依托单位: UNIVERSITY OF MARYLAND BALTIMORE
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-02-23 至 2014-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8416369
• 关键词: Admission activity; Americas; Antibiotic Resistance; Antibiotics; Antimicrobial Resistance; Area; Award; Centers for Disease Control and Prevention (U.S.); Clinical; Clinical Research; Cohort Studies; Communicable Diseases; Confounding Factors (Epidemiology); Country; Data; Databases; Disease; Doctor of Philosophy; Enterococcus; Epidemiologic Methods; Epidemiology; Equation; Faculty; Funding; Future; Genes; Genetic; Goals; Gram-Negative Bacteria; Grant; Health; Healthcare; Hospitals; Imipenem; Incidence; Individual; Infection Control; Intensive Care Units; Intervention; Intervention Trial; Lead; Manuscripts; Maryland; Medical; Medical center; Mentored Patient-Oriented Research Career Development Award; Mentors; Modeling; Molecular; Nosocomial Infections; Nurses; Nursing Research; Outcome; Patients; Persons; Policies; Population Study; Principal Investigator; Process; Pseudomonas aeruginosa; Publishing; Pulsed-Field Gel Electrophoresis; Randomized; Randomized Clinical Trials; Relative (related person); Research; Resistance; Resistance development; Risk; Risk Factors; Societies; Specimen; Students; Surgical Intensive Care; Techniques; Therapeutic Intervention; Time; United States National Institutes of Health; Universities; Vancomycin resistant enterococcus; Work; Writing; base; career; cohort; cost effective; cost effectiveness; design; gene therapy; improved; markov model; meetings; member; novel; patient oriented research; programs; resistance mechanism; resistant strain; sample collection; skills; transmission process

DESCRIPTION (provided by applicant): This proposal is for a five year K24 Mid-Career Development Award for patient-oriented research and mentoring for Anthony Harris MD, MPH. The proposal involves research and mentoring in the areas of antimicrobial resistance and hospital epidemiology. At present, he is the principal investigator on one NIH R01 and one CDC R01. During his eight years as a faculty member, he has published more than 70 manuscripts. He has mentored a number of PhD epidemiology students and infectious disease fellows to successful academic careers and has received a mentoring award from the Society of Healthcare Epidemiology of America. He is internationally recognized for his work in the areas of antimicrobial resistance and hospital epidemiology. Dr. Harris is requesting this award to dedicate 50% of his time to mentoring, writing new grants in the areas of infection control interventions aimed at decreasing the emergence of antimicrobial resistance and nosocomial infections, and taking coursework in clinical trials and randomized-cluster design that will improve his patient-oriented research. This award will allow him to decrease his administrative and clinical responsibilities to allow more protected time for mentoring and research. This award will help him achieve his long-term goals, which include: 1) decreasing the incidence of nosocomial infections and decrease the emergence of antimicrobial resistance 2) continuing to successfully obtain NIH R01 funding in the areas of antimicrobial resistance and hospital epidemiology 3) continuing to move his patient-oriented research towards intervention trials including randomized-cluster intervention trials 4) continuing to develop his mentoring skills to mentor trainees to successfully pursue academic clinical research careers.

描述（由申请人提供）：本提案旨在为 Anthony Harris 医学博士、公共卫生硕士颁发为期五年的 K24 中期职业发展奖，以表彰其以患者为导向的研究和指导。该提案涉及抗菌素耐药性和医院流行病学领域的研究和指导。目前，他是一项 NIH R01 和一项 CDC R01 的首席研究员。在担任教职的八年里，他发表了 70 多篇手稿。他指导了许多流行病学博士生和传染病研究员取得了成功的学术生涯，并获得了美国医疗保健流行病学协会颁发的指导奖。他因其在抗菌素耐药性和医院流行病学领域的工作而获得国际认可。哈里斯博士请求获得这一奖项，将他 50% 的时间用于指导、在感染控制干预领域撰写新的资助金，旨在减少抗菌素耐药性和医院感染的出现，并参加临床试验和随机集群设计课程，以改善他以患者为导向的研究。该奖项将使他能够减少行政和临床职责，从而为指导和研究提供更多受保护的时间。该奖项将帮助他实现长期目标，其中包括：1) 降低医院感染发生率并减少抗菌素耐药性的出现 2) 继续成功获得抗菌素耐药性和医院流行病学领域的 NIH R01 资助 3) 继续将其以患者为中心的研究转向包括随机集群干预试验在内的干预试验 4) 继续发展他的指导技能 指导学员成功从事学术临床研究职业。