K24 Clinical Research in Antimicrobial Resistance and Hospital Epidemiology

K24 抗菌药物耐药性和医院流行病学临床研究

• 批准号: 8211047
• 负责人: ANTHONY D HARRIS
• 金额: $ 18万
• 依托单位: UNIVERSITY OF MARYLAND BALTIMORE
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-02-23 至 2014-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8211047
• 关键词: Admission activity; Americas; Antibiotic Resistance; Antibiotics; Antimicrobial Resistance; Area; Award; Centers for Disease Control and Prevention (U.S.); Clinical; Clinical Research; Cohort Studies; Communicable Diseases; Confounding Factors (Epidemiology); Country; Data; Databases; Disease; Doctor of Philosophy; Enterococcus; Epidemiologic Methods; Epidemiology; Equation; Faculty; Funding; Future; Genes; Genetic; Goals; Gram-Negative Bacteria; Grant; Health; Healthcare; Hospitals; Imipenem; Incidence; Individual; Infection Control; Intensive Care Units; Intervention; Intervention Trial; Lead; Manuscripts; Maryland; Medical; Medical center; Mentored Patient-Oriented Research Career Development Award; Mentors; Modeling; Molecular; Nosocomial Infections; Nurses; Nursing Research; Outcome; Patients; Persons; Policies; Population Study; Principal Investigator; Process; Pseudomonas aeruginosa; Publishing; Pulsed-Field Gel Electrophoresis; Randomized; Randomized Clinical Trials; Relative (related person); Research; Resistance; Resistance development; Risk; Risk Factors; Societies; Specimen; Students; Surgical Intensive Care; Techniques; Therapeutic Intervention; Time; United States National Institutes of Health; Universities; Vancomycin resistant enterococcus; Work; Writing; base; career; cohort; cost effective; cost effectiveness; design; gene therapy; improved; markov model; meetings; member; novel; patient oriented research; programs; resistance mechanism; resistant strain; sample collection; skills; transmission process

DESCRIPTION (provided by applicant): This proposal is for a five year K24 Mid-Career Development Award for patient-oriented research and mentoring for Anthony Harris MD, MPH. The proposal involves research and mentoring in the areas of antimicrobial resistance and hospital epidemiology. At present, he is the principal investigator on one NIH R01 and one CDC R01. During his eight years as a faculty member, he has published more than 70 manuscripts. He has mentored a number of PhD epidemiology students and infectious disease fellows to successful academic careers and has received a mentoring award from the Society of Healthcare Epidemiology of America. He is internationally recognized for his work in the areas of antimicrobial resistance and hospital epidemiology. Dr. Harris is requesting this award to dedicate 50% of his time to mentoring, writing new grants in the areas of infection control interventions aimed at decreasing the emergence of antimicrobial resistance and nosocomial infections, and taking coursework in clinical trials and randomized-cluster design that will improve his patient-oriented research. This award will allow him to decrease his administrative and clinical responsibilities to allow more protected time for mentoring and research. This award will help him achieve his long-term goals, which include: 1) decreasing the incidence of nosocomial infections and decrease the emergence of antimicrobial resistance 2) continuing to successfully obtain NIH R01 funding in the areas of antimicrobial resistance and hospital epidemiology 3) continuing to move his patient-oriented research towards intervention trials including randomized-cluster intervention trials 4) continuing to develop his mentoring skills to mentor trainees to successfully pursue academic clinical research careers.

描述（由申请人提供）：该提案是为安东尼哈里斯医学博士，公共卫生硕士面向患者的研究和指导五年K24中期职业发展奖。该提案涉及抗菌素耐药性和医院流行病学领域的研究和指导。目前，他是一个NIH R01和一个CDC R01的首席研究员。在他担任教职的八年里，他发表了70多篇手稿。他指导了许多流行病学博士生和传染病研究员成功的学术生涯，并获得了美国医疗保健流行病学协会的指导奖。他在抗菌素耐药性和医院流行病学领域的工作得到国际认可。Harris博士要求将50%的时间用于指导，在感染控制干预措施领域撰写新的赠款，旨在减少抗生素耐药性和医院感染的出现，并参加临床试验和随机分组设计的课程，这将改善他以患者为导向的研究。这一奖项将使他能够减少他的行政和临床责任，让更多的时间保护指导和研究。这个奖项将帮助他实现他的长期目标，其中包括：1）降低医院感染的发生率，减少抗生素耐药性的出现2）继续成功地获得NIH R01在抗生素耐药性和医院流行病学领域的资助3）继续将他以患者为导向的研究转向干预试验，包括随机分组干预试验4）继续发展他的指导技能，指导学员成功地从事学术临床研究事业。