Program in Genetics and Genomics PhD Training Grant

摘要： 这是一项新的申请，旨在支持12名研究生攻读遗传学博士课程的第二年 和哈佛医学院的基因组学(PGG)。遗传学和基因组学领域的科学家在 这是我们国家努力了解生命如何运作以及诊断和治疗人类疾病的前沿。这个 PGG的使命是为不同的学生群体提供智力、技术和专业培训 他们将需要成为遗传学和基因组学领域的未来领导者。培训来自于 定制课程，强调研究、技术培训、培训的严谨性和可重复性 科学交流、职业关系网、行业实习机会，当然还有论文 研究。PGG学生在40个中心实验室中的一个进行博士研究，但不是排他性的 致：HMS遗传学系。培训教师的实验室资金充足，研究范围广泛。 遗传学和基因组学领域的主题，从原核基因调控到人类生物学 和疾病。由培训基金资助的学生是生物和生物医学科学(BBS)的一部分。 HMS的项目，这是一个大型的伞形项目，每年吸引一批顶尖的研究生。 PGG为一群自选的BBS学生提供了成为紧密社区的一部分的机会 侧重于遗传学和基因组学领域的技术和专业培训。需要PGG学生 集中在遗传学和基因组学领域的课程工作，包括要求至少参加 一门课程是生物数据的定量分析，另一门课程公开涵盖了严谨和 现代生物医学研究中的重复性。PGG的学生还参加了一系列程序性活动， 包括(1)年度研讨会，(2)出席学生主导的月度研究报告并发表演讲，3) 与志同道合的高年级学生和博士后建立联系的机会，包括那些学习临床的人 遗传学，以及(4)邀请外部遗传学或基因组学科学家参加研讨会。学生们将被引导 在项目顾问和论文咨询委员会(DAC)的课程和轮换选择中， 将包括PGG培训师。学生的进步将通过课程成绩、PA评估、DAC更新、 G3研究讲座，以及教职员工出席遗传学系数据俱乐部系列学生研讨会的情况。 PGG课程和政策将以循证教学方法为指导，纳入课程， 通过课程和方案评估，以及由PGG培训员和高级PGG组成的指导委员会 学生们。综合起来，培训计划将为PGG学生提供成为该领域领导者所需的技能 并领导未来的努力，利用遗传学和基因组科学促进人类 健康。

Abstract: This is a new application to support twelve graduate students in their second year of a Ph.D. Program in Genetics and Genomics (PGG) at Harvard Medical School (HMS). Scientists in the fields of genetics and genomics are at the forefront of our Nation’s efforts to understand how life works and to diagnose and treat human disease. The mission of PGG is to provide a diverse group of students with the intellectual, technical, and professional training that they will need to become future leaders in the fields of genetics and genomics. Training derives from a customized curriculum, which emphasizes rigor and reproducibility in research, technical training, training in scientific communication, professional networking, industry internship opportunities, and, of course, dissertation research. PGG students carry out Ph.D. research in one of forty laboratories centered around, but not exclusive to, the Department of Genetics at HMS. Laboratories of training faculty are well-funded and study a wide range of topics in the fields of genetics and genomics, which range from prokaryotic gene regulation to human biology and disease. Students supported by the training grant are part of the Biological and Biomedical Sciences (BBS) program at HMS, which is a large umbrella program that draws in a top group of graduate students each year. PGG provides a self-selected group of BBS students with the opportunity to be part of a close-knit community focused on technical and professional training in the area of genetics and genomics. PGG students are required to concentrate their course work in the fields of genetics and genomics, including a requirement to take at least one course in the quantitative analysis of biological data, and one course overtly covering the need for rigor and reproducibility in modern biomedical research. PGG students also participate in a set of programmatic activities, including (1) an annual symposium, (2) attend and present at student-led monthly research presentations, 3) networking opportunities with like-minded senior students and postdocs, including those studying clinical genetics, and (4) hosting outside genetics or genomics-oriented scientists for seminars. Students will be guided in courses and rotation selections by Program Advisors and by Dissertation Advisory Committees (DAC), which will include PGG trainers. Student progress will be monitored via course grades, PA evaluations, DAC updates, G3 research talks, and by faculty attendance at student seminars in the Genetics Department Data Club series. PGG curriculum and policy will be guided by evidence-based teaching approaches incorporated into curriculum, by course and program evaluations, and by a Steering Committee composed of PGG trainers and senior PGG students. Together, the training plan will give PGG students the skills they need to become leaders in the fields of genetics and genomics and to lead future efforts using the genetics and genomic sciences to promote human health.