Administrative Core

行政核心

• 批准号: 10654584
• 负责人: MARCIA Roxana CRUZ-CORREA
• 金额: $ 45.3万
• 依托单位: UNIVERSITY OF PUERTO RICO MED SCIENCES
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-02 至 2025-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10654584
• 关键词: Achievement; Address; Advisory Committees; Affect; Area; Authorization documentation; Basic Science; Cardiometabolic Disease; Caribbean Hispanic; Caring; Clinical; Clinical Research; Collaborations; Communicable Diseases; Communication; Communities; Community Health; Development; Disasters; Disease; Emerging Communicable Diseases; Ensure; Evaluation; Foundations; Funding; Goals; Government Agencies; Health; Health Sciences; Healthcare; Hispanic; Hispanic Populations; Hospitals; Infrastructure; Institution; Island; Lead; Leadership; Malignant Neoplasms; Medical; Modeling; Monitor; Policies; Population; Positioning Attribute; Procedures; Productivity; Puerto Rico; Research; Research Infrastructure; Research Institute; Research Personnel; Resource-limited setting; Resources; Science; Services; Structure; Support System; Translating; Translational Research; United States National Institutes of Health; Universities; authority; base; clinical development; clinical translation; collaboratory; community organizations; cost effective; cost efficient; design; experience; flexibility; improved; innovation; medical schools; medically underserved; medically underserved population; multidisciplinary; operation; organizational structure; outreach; programs; skills; tool

ABSTRAC- ADMINISTRATIVE CORE There is a need for well-coordinated infrastructure, multi-institutional and multidisciplinary collaborative networks that target specific populations and facilitate high-quality, cost-efficient and regulatory compliant research and health care strategies. The Hispanic Alliance for Clinical and Translational Research (the Alliance) will integrate clinical and translational research infrastructure and resources across a predominantly Hispanic U.S. jurisdiction to bridge the gaps between basic and clinical translational research, to address severe health conditions that disproportionately affect the medically underserved, and highly prevalent among Hispanic populations. The long-term goal of the Administrative Core of the Alliance is to provide a model for the optimal management and development clinical and translational research infrastructure in resource-limited settings that provide care to medically underserved populations. The specific objective of the Administrative Core will be to establish a leadership and management structure that will ensure that the Alliance KCA’s and milestones are met effectively and efficiently and when necessary realign the existing institutional and Alliance resources. This will be accomplished through three specific aims: 1) Provide an integrated organizational structure, leadership and advisory support system to effectively supervise, manage and monitor progress of all the Alliance key component activities/cores leading to achievement of the proposed milestones; 2) Develop and implement policies, procedures, and practices that ensure efficiency, sustainability, and scientific and fiscal flexibility to accommodate the changing needs and priorities of the Investigators, leading to new innovative and competitive areas of clinical and translational research; 3) Provide timely financial, dissemination, communication and evaluation functions that promote expansion of innovative clinical and translational research and services and long-term sustainability of the Alliance. The proposed administrative structure will bring together key leaders from the participating Institutions and external collaborators, further developing a pre-existing collaborative structure that has been successful in obtaining external funding and developing early-stage investigators. It will provide an efficient and integrated governance and administrative structure that will ensure the optimal and cost-effective utilization of resources. This will ultimately lead to successful advances in Clinical and Translational research in prevalent conditions in our population.

摘要-行政核心 需要有协调良好的基础设施、多机构和多学科 合作网络，针对特定人群，促进高质量，成本效益高， 合规研究和医疗保健战略。西班牙裔临床和 转化研究（联盟）将整合临床和转化研究 基础设施和资源在一个主要是西班牙裔美国司法管辖区，以弥补差距 在基础和临床转化研究之间，以解决严重的健康状况， 不成比例地影响医疗服务不足的人，在西班牙裔中非常普遍， 人口。联盟行政核心的长期目标是提供一种模式， 用于优化管理和开发临床和转化研究基础设施， 为医疗服务不足的人群提供护理的资源有限的环境。具体 行政核心的目标是建立一个领导和管理结构 这将确保联盟KCA和里程碑有效和高效地实现， 必要时，重新调整现有的机构和联盟资源。这将是 通过三个具体目标来实现：1）提供一个综合的组织结构， 有效监督、管理和监测进展的领导和咨询支助系统 联盟的所有关键组成部分活动/核心，以实现拟议的 里程碑; 2）制定和实施政策，程序和实践，以确保效率， 可持续性，以及科学和财政灵活性，以适应不断变化的需求和优先事项 研究者，导致新的创新和竞争领域的临床和翻译 （3）提供及时的财务、传播、交流和评估职能， 促进扩大创新的临床和转化研究和服务， 联盟的可持续性。拟议的行政结构将汇集主要领导人 从参与机构和外部合作者，进一步发展一个预先存在的 成功获得外部资金和发展的合作结构 早期调查员它将提供一个有效和综合的治理和行政 这将确保以最佳和具有成本效益的方式利用资源。这将最终 导致临床和转化研究在我们的普遍条件下取得成功的进展 人口