Hispanic Alliance for Clinical and Translational Research (Alliance)

西班牙裔临床和转化研究联盟（联盟）

• 批准号: 10027567
• 负责人: MARCIA Roxana CRUZ-CORREA
• 金额: $ 300万
• 依托单位: UNIVERSITY OF PUERTO RICO MED SCIENCES
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-02 至 2025-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10027567
• 关键词: Academia; Address; Adoption; Affect; Bioinformatics; Biometry; Clinical; Clinical Research; Collaborations; Communicable Diseases; Communication; Communities; Community Health; Community Networks; Development; Development Plans; Disasters; Disease; Emerging Communicable Diseases; Ensure; Epidemiology; Evaluation; Foundations; Funding; Generations; Goals; Government; Health; Health Policy; Health Sciences; Healthcare; Hispanics; Human Resources; Infrastructure; Institution; Island; Knowledge; Laboratories; Lead; Leadership; Malignant Neoplasms; Medical; Mentors; Methods; Mission; Modeling; Outcome; Participant; Pilot Projects; Population; Positioning Attribute; Process; Public Health; Puerto Rico; Research; Research Design; Research Personnel; Resources; Safety; Science; Scientist; Services; Specific qualifier value; Structure; Subgroup; System; Technology; Training; Training Activity; Training Support; Translational Research; United States; United States National Institutes of Health; Universities; Work; base; biomedical informatics; cardiometabolism; career development; community center; cyber infrastructure; data infrastructure; data warehouse; dissemination research; effective therapy; epidemiology study; health care delivery; health data; improved; innovation; interdisciplinary collaboration; medical schools; medically underserved; next generation; outreach; programs; recruit; research and development; research facility; statistics; translational research program

Improving health care for the medically underserved, including our Hispanic population, afflicted by prevalent diseases, such as cancer, cardio-metabolic and infectious diseases, remains a major challenge. The current application is to support the development of Hispanic Alliance for Clinical & Translational Research in Puerto Rico (Alliance), which aims to build on the existing infrastructure of the Puerto Rico Clinical and Translational Research Consortia (PR-CTRC an RCMI-CTR) and the unique expertise on emerging infectious diseases and the study of disaster-related conditions and their impact on Health. The objective of the Alliance is to serve as the catalytic center to enhance the competitiveness of investigators to conduct research and obtain additional funding for clinical and translational research addressing highly prevalent diseases and those that affect the medically underserved in Puerto Rico. The long-term goal of the Alliance is to transform clinical and translational research in Hispanic populations in the Mainland and in Puerto Rico by promoting inter-disciplinary collaboration and leverage of resources to address diseases affecting Hispanic communities. Successful implementation of the Alliance will advance our fundamental knowledge of Hispanic health in this ethnic subgroup, which is increasingly represented in the U.S. mainland population. The Alliance is innovative because it will: (1) create a Hispanic-centered research hub integrating resources to support researchers in PR and national partners; (2) implement the Hispanic Real World clinical research data warehouse; and (3) establish a Community Health & Research Council comprised of diverse community partners emphasizing a community-centered, bi-directional research focus to impact health policy and ultimately improving health outcomes in our Hispanic community. The Alliance overall aims are specified below. Specific Aim 1: Enhance an island-wide infrastructure and human resource network and synergize with local and national partners to conduct clinical and translational research in Puerto Rico. Specific Aim 2: Provide professional development activities to enhance the ability of investigators to develop competitive clinical and translational research programs with emphasis on Hispanic health needs. Specific Aim 3: Facilitate the generation and dissemination of knowledge to and from the bench and the community to improve health outcomes that affect Hispanic communities in Puerto Rico and across United States. Specific Aim 4: Catalyze and sustain the integration of trans/multi/inter disciplinary collaborations to conduct clinical and translational research within and across institutions, organizations, community networks and health programs in Puerto Rico and other IDeA states.

改善医疗服务不足的人的医疗保健，包括我们的西班牙裔人口，他们受到 流行的疾病，如癌症、心脏代谢疾病和传染病，仍然是一个重大挑战。 目前的申请是为了支持拉美裔临床和翻译研究联盟的发展 在波多黎各(联盟)，旨在加强波多黎各临床和医疗中心的现有基础设施 翻译研究联盟(PR-CTRC和RCMI-CTR)和关于新发传染病的独特专业知识 疾病和灾害相关状况及其对健康影响的研究。联盟的目标 是作为催化中心，增强调查人员开展研究和 获得更多资金，用于临床和转化性研究，解决高度流行的疾病和 那些影响波多黎各医疗服务不足的人。联盟的长期目标是 通过以下方式转变大陆和波多黎各拉美裔人口的临床和翻译研究 促进跨学科协作和利用资源，以应对影响 西班牙裔社区。 该联盟的成功实施将促进我们对拉美裔健康的基本了解 在这个种族亚群中，这一群体在美国大陆人口中的代表性越来越大。联盟是 创新是因为它将：(1)创建以西班牙裔为中心的研究中心，整合资源以支持 公关研究人员和国家合作伙伴；(2)实施西班牙裔真实世界临床研究数据 (3)建立一个由不同社区组成的社区卫生与研究理事会 合作伙伴强调以社区为中心的双向研究重点，以影响卫生政策和 最终改善我们拉美裔社区的健康状况。明确了联盟的总体目标 下面。 具体目标1：加强全岛基础设施和人力资源网络，并与当地 和国家合作伙伴在波多黎各开展临床和转化性研究。 具体目标2：提供专业发展活动，以提高调查人员的发展能力 具有竞争力的临床和转化性研究项目，重点关注西班牙裔的健康需求。 具体目标3：促进知识的产生和传播 社区改善影响波多黎各和全美拉美裔社区的健康结果 各州。 具体目标4：促进和维持跨学科/多学科/跨学科协作的一体化，以开展 机构、组织、社区网络和卫生机构内部和跨机构、组织、社区网络和卫生部门的临床和转化性研究 波多黎各和其他IDEA州的项目。