Core A: Administrative Core

核心A：行政核心

• 批准号: 10698072
• 负责人: Wendy K Chung
• 金额: $ 16.03万
• 依托单位: COLUMBIA UNIVERSITY HEALTH SCIENCES
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-09-06 至 2027-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10698072
• 关键词: Address; Administrative Efficiency; Administrator; Advisory Committees; Brain; Child; Clinical; Collaborations; Communication; Communities; Computer Analysis; Data; Data Set; Development; Diagnosis; Doctor of Philosophy; Early Diagnosis; Early identification; Ensure; Environment; Ethics; Evaluation; Family; Fostering; Foundations; Genetic Risk; Genomics; Goals; Hospitals; Individual; Institution; Interdisciplinary Study; Intervention; Knowledge; Leadership; Medical center; Modeling; Monitor; New York; Parents; Policies; Positioning Attribute; Presbyterian Church; Psychiatry; Psychology; Publications; Quality Control; Recommendation; Research; Research Personnel; Research Project Grants; Resources; Seminal; Site; Statistical Data Interpretation; Strategic Planning; Structure; Systems Biology; Universities; Work; autism spectrum disorder; career development; clinical practice; cohort; cost effective; experience; genetic information; innovation; inter-institutional; marginalization; medical schools; meetings; member; multidisciplinary; neurobehavioral; operation; outreach; pediatric department; programs; prospective; synergism

PROJECT SUMMARY The Administrative (Admin) Core will provide research and logistical oversight and facilitate communication among the Projects and Cores of the Prospective Genetic Risk Evaluation and Assessment (PROGRESS) in Autism Center. The Admin Core’s goal is to foster a PROGRESS Center environment that allows for the complementary and synergistic execution of the proposed multidisciplinary research that will identify and partner with a cohort of families whose children are at identified genetic risk (IGR) for autism (Project 1), understand the impact of this genetic information on parents and families (Project 2), and examine neurobehavioral trajectories of PROGRESS Cohort children across development (Project 3). In addition to supporting these three Projects, the Admin Core will support the other Core Components: the Assessment Core, the Statistical and Computational Analysis (SCA) Core, and the Dissemination and Outreach (D&O) Core. The Admin Core will have three main functions. The first function is scientific leadership and integration, providing programmatic governance to maximize synergy, efficiency and impact of our research. The Admin Core leadership is composed of the Executive Committee (Center Director and Co-Director, Director of Operations, Director of Finance, and a Program Coordinator) and a Steering Committee (all Project and Core Leads and Co-Leads). Admin Core function includes programmatic coordination of the Center Research Projects and Cores, strategic planning of short- and long-term goals, and ethical considerations of the implications of our genomic research. Secondly, the Admin Core will provide management to deliver centralized administrative, fiscal, organizational, and communications coordination of the PROGRESS Center. The Projects and Cores span Columbia University, the New York State Psychiatric Institute, and Weill Cornell Medical Center, thus requiring central governance and organization that will be provided by inter-institutional coordination and communication by the Admin Core. Finally, the Admin Core will ensure added value and scientific rigor of the PROGRESS Center Research Projects and Cores through Center Evaluation. The Admin Core will interface with an External Advisory Committee (EAC) of experts in fields relevant to autism research. The Admin Core will respond to recommendations made by the EAC, as well as recommendations made by a Community Advisory Board (CAB) to address scientific and community concerns and increase the PROGRESS Center’s national and global influence on scientific and clinical practice. The Admin Core will therefore provide seamless integration of the various PROGRESS Center Components at multiple sites to produce high quality and meaningful data that will aid in early identification and management of identified genetic risk for developing autism.

项目摘要 行政（管理）核心将提供研究和后勤监督，并促进沟通 前瞻性遗传风险评估（PROGRESS）的项目和核心 自闭症中心。Admin Core的目标是建立一个PROGRESS Center环境， 互补和协同执行拟议的多学科研究，将确定和合作伙伴 与一组其子女有自闭症遗传风险（IGR）的家庭（项目1），了解 这种遗传信息对父母和家庭的影响（项目2），并检查神经行为轨迹 跨发展组群儿童（项目3）。除了支持这三个项目外， 管理核心将支持其他核心组件：评估核心、统计和 计算分析（SCA）核心，以及传播和推广（D&O）核心。管理核心将 有三个主要功能。第一个功能是科学领导和整合，提供纲领性 治理，以最大限度地发挥协同作用，效率和我们的研究的影响。管理核心领导层是 由执行委员会（中心主任和联合主任，业务主任， 财务和计划协调员）和指导委员会（所有项目和核心领导和共同领导）。 行政核心职能包括中心研究项目和核心的方案协调，战略 短期和长期目标的规划，以及对我们基因组研究影响的伦理考虑。 其次，管理核心将提供管理，以提供集中的行政，财政， 组织和沟通协调的进步中心。项目和核心跨越 哥伦比亚大学、纽约州立精神病研究所和威尔康奈尔医学中心，因此需要 通过机构间协调和沟通提供中央治理和组织 管理核心。最后，管理核心将确保进步的附加值和科学严谨性 通过中心评估的中心研究项目和核心。管理核心将与 外部咨询委员会（EAC），由自闭症研究相关领域的专家组成。管理员核心将响应 选管会的建议，以及社区咨询委员会的建议， (CAB)解决科学和社区的关注，并增加进步中心的国家和全球 影响科学和临床实践。因此，管理核心将提供 多个地点的各种PROGRESS Center组件可生成高质量且有意义的数据， 帮助早期识别和管理已识别的自闭症遗传风险。