权益分类	功能权益	普通用户	{{item.name}}会员
{{category.name}}	{{benefitItem.name}}

Mental Health in Autistic Adults: And RDoC Approach

成人自闭症患者的心理健康：和 RDoC 方法

基本信息

批准号：
10698093
负责人：
Carla A Mazefsky
金额：
$ 25.64万
依托单位：
UNIVERSITY OF PITTSBURGH AT PITTSBURGH
依托单位国家：
美国
项目类别：
财政年份：
2022
资助国家：
美国
起止时间：
2022-09-06 至 2027-06-30
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10698093
关键词：
Adult Advocacy Age Ally Brain Calibration Categories Clinical Comprehension Data Development Diagnosis Dimensions Ensure Equipment and supply inventories Factor Analysis Feeling suicidal General Population Generations Goals Growth Hour Individual Information Systems Life Measures Mental Health Modeling Negative Valence Outcome Measure Participant Patient Outcomes Assessments Patient Self-Report Positive Valence Probability Process Psychometrics Quality of life Questionnaires Reporting Research Research Domain Criteria Risk Risk Factors Safety Sampling Sensory Social Processes Subgroup Suicide Suicide attempt Symptoms System Testing Time Training United States National Institutes of Health Work adult with autism spectrum disorder autism spectrum disorder autistic burnout cognitive interview cognitive system demographics design human old age (65+)improved indexing individuals with autism spectrum disorder machine learning model prospective psychosocial random forest response screening sex sound suicidal suicidal behavior suicidal risk suicide model suicide rate theories therapy development trait

项目摘要

ABSTRACT- Project 1 Suicide rates in autistic adults are alarming high in recent research; 4- 72% have endorsed suicidal ideation and 4-33% have engaged in suicidal behavior or attempts. Both scientific and advocacy groups have endorsed research for effective suicidality assessment and identification of risk factors. However, existing suicidality screening measures do not seem to function in the same way for autistic adults, and to date, no research has used a measure of suicide risk rather than a screen of imminent risk. Adaptation of existing suicide screens may be insufficient, given evidence that autistic adults may have unique risk factors, such as camouflaging of autistic traits and autistic burnout. This study will develop a suicidality measure for autistic adults, the Autism Suicidality Inventory, that will capture a continuum of suicide risk. Autistic adults and their allies will refine an item pool, and 25 autistic adults (at least 10 of which with suicidality) will complete cognitive interviews of the drafted items to ensure clarity and comprehension. A sample of 1000 autistic and non-autistic adults will complete the drafted questionnaire and a related online battery of measures to evaluate the dimensionality of the item pool, conduct Item Response Theory calibration, and compare existing suicide measures to the proposed questionnaire via IRT co-calibration. A subsample of 300 autistic and non-autistic participants (the ACE core sample) will repeat the measure every two months for a year, and cross-project analyses will examine whether those who report more suicidality baseline also report more suicidal ideation in daily life, model suicide risk over time via latent growth models, and identify factors that are most strongly associated with suicidality trajectories. The Autism Suicidality Inventory will be the first validated suicide propensity measure developed for ASD, designed with input from autistic adults and capturing a continuum of risk via an emphasis on processes that relate to risk. The availability of such a measure is essential to inform intervention development to improve safety and quality of life.

摘要-项目1