Skeletal, Craniofacial and Oral Biology Training Grant

项目摘要： 这是一项关于继续进行Skeleton、颅面和口腔机构培训方案的建议 生物学在康州大学健康，牙科医学院作为一个T90/R90计划。它旨在帮助满足 大量需要接受过与改善口腔、牙齿和颅面有关的研究培训的独立科学家 美国的健康。该计划已经并将继续培训学者（DMD和非DMD）谁是 有能力作为临床医生和独立科学家，能够启动和维持资助的研究 计划，谁了解多学科研究，谁是他们的研究的演变做好准备 新方向研究培训领域包括组织工程和再生医学，细胞 和癌症生物学，计算生物学，基因组学和生物信息学，颅面和骨骼生物学， 基因调控，免疫学，微生物组/微生物学，口腔生物学，干细胞生物学，临床和 翻译研究该培训计划的主要轨道是（一）DMD/博士（7-8年的培训，3- 该培训补助金提供5年的支持; 4名现有受训人员，1-4名（取决于F30的成功） ㈡博士（4-5年培训，3年支助; 3名现有学员，6名 要求增加受训人员），㈢博士后研究（3年培训和支助; 3名现有受训人员， （iv）非公民博士生（拥有DDS学位）（3-5年培训， 年的支助; 1名现有受训人员，2名要求增加的受训人员）。我们将培训个人与广泛的 一系列的背景，从那些与BS/BA学位，以那些谁已经完成博士和/或牙科 住院医师培训为了为我们的学者/学员提供坚实的共同基础，我们开发了核心 要求所有受训人员在所有培训轨道上开展的活动。我们正在引入几个新的程序功能（i） 确保实现培训里程碑，（ii）促进受训人员准备F和K奖励，（iii）更好地 为我们的DMD/博士整合临床和研究培训，以促进向学术生涯的过渡， (iv)教学和实验室管理的职业发展计划。UConn Health拥有一个充满活力的团队， 在各个研究领域的教师与整个学校的教师之间非常成功的合作 和杰克逊基因组医学实验室。生物医学科学 博士课程研究生教师，积极和新的机构研究中心和临床计划提供 当代实验室，翻译和患者为导向的研究机会，使多元化 培训环境的计划轨道，允许灵活性为学员的个人需求，并确保 顺利通过轨道。该机构有积极的实习生招聘计划。几个是 针对代表性不足的少数民族候选人。我们将继续提供量身定制的培训， 每个候选人通过座谈会，研讨会，课程，临床研究中心和合作研究 这些活动既被整合在单个轨道内，也被整合在该计划的所有轨道之间。

Project Summary: This is a proposal for the continuation of the Institutional Training Program in Skeletal, Craniofacial and Oral Biology at the UConn Health, School of Dental Medicine as a T90/R90 program. It is intended to help meet the substantial need for independent scientists trained in research related to improving oral, dental and craniofacial health in the United States. The program has and will continue to train scholars (DMD and non-DMD) who are competent as clinicians and independent scientists, who are able to initiate and maintain funded research programs, who understand multidisciplinary research and who are prepared for the evolution of their research into new directions. Areas of research training include Tissue Engineering and Regenerative Medicine, Cell and Cancer Biology, Computational Biology, Genomics and Bioinformatics, Craniofacial and Skeletal Biology, Gene Regulation, Immunology, Microbiome/Microbiology, Oral Biology, Stem Cell Biology, and clinical and translational research. The major tracks of the training program are the (i) DMD/PhD (7-8 yrs of training with 3- 5 yrs of support from this training grant; 4 present trainees, 1-4 (depending on success of F30s) additional trainees requested over five yrs), (ii) PhD (4-5 yrs of training with 3 yrs of support; 3 present trainees, 6 additional trainees requested), (iii) postdoctoral research (3 yrs training and support; 3 present trainees, 5 additional trainees requested) and (iv) non-citizen PhD trainees (with DDS degrees) (3-5 yrs of training with 3 yrs of support; 1 present trainees 2 additional trainees requested). We will be training individuals with a broad range of backgrounds, from those with BS/BA degrees to those who have completed PhD and/or dental residency training. To provide a solid, common foundation for our scholars/trainees, we have developed Core Activities required of all trainees in all training tracks. We are introducing several new program features to (i) insure training milestones are achieved, (ii) facilitate preparation of F and K awards by trainees, (iii) better integrate clinical and research training for our DMD/PhDs to enhance transition into an academic career, and (iv) career development plans for teaching and laboratory management. UConn Health has a dynamic group of faculty in various areas of research with highly successful collaborations among faculty throughout the Schools of Dental Medicine and Medicine and The Jackson Laboratory for Genomic Medicine. The Biomedical Science PhD program graduate faculty, active and new institutional research centers and clinical programs provide contemporary laboratory, translational and patient oriented research opportunities that enable a diversified training environment for the program tracks, allow flexibility for the individual needs of trainees, and ensure successful progress through the tracks. The institution has vigorous trainee recruitment programs. Several are directed towards under-represented minority candidates. We will continue to provide training that is tailored to each candidate through symposia, seminars, courses, clinical research centers and collaborative research activities which are integrated both within individual tracks and amongst all the tracks of the program.