Skeletal, Craniofacial and Oral Biology Training Grant

项目总结： 这是一项关于继续开展骨骼、颅面和口腔机构培训计划的建议 康涅狄格州大学卫生学院牙医学院的生物学T90/R90课程。它的目的是帮助满足 大量需要受过口腔、牙科和颅面改善相关研究培训的独立科学家 美国的健康状况。该方案已经并将继续培训符合以下条件的学者(DMD和非DMD) 作为临床医生和独立科学家，能够发起和维持资助研究 计划，了解多学科研究，并为其研究的发展做好准备 进入新的方向。研究培训领域包括组织工程和再生医学、细胞 和癌症生物学，计算生物学，基因组学和生物信息学，颅面和骨骼生物学， 基因调控、免疫学、微生物组/微生物学、口腔生物学、干细胞生物学、临床和 翻译研究。培训计划的主要途径是(I)DMD/PHD(7-8年3-8年培训) 为期5年的培训资助；4名现职学员，1-4名(视F30的成功情况而定) 受训人员要求五年以上)，(二)博士学位(四至五年的培训和三年的支助；三名目前的受训人员，6 (3)博士后研究(3年培训和支助；3名现职学员，5名 (4)非公民博士受训人员(拥有DDS学位)(3-5年，共3年) 年的支持；1名目前的实习生，2名额外的实习生)。我们将通过广泛的培训来训练个人 背景范围广泛，从拥有学士/学士学位的人到完成博士和/或牙科学位的人 住院医师培训。为了为我们的学者/实习生提供坚实、共同的基础，我们开发了Core 要求所有受训人员在所有培训轨道上开展的活动。我们正在为(I)引入几个新的程序功能 确保实现培训里程碑，(Ii)促进学员准备F和K奖，(Iii)更好地 将临床和研究培训整合到我们的DMD/博士，以促进向学术职业的过渡，以及 (4)教学和实验室管理的职业发展计划。康涅狄格州大学健康中心有一个充满活力的组织 在各个研究领域的教职员工与整个学院的教职员工非常成功地合作 牙科医学和医学部和杰克逊基因组医学实验室。生物医学科学 博士项目研究生教师、活跃的和新的机构研究中心和临床项目提供 当代实验室、翻译和以患者为导向的研究机会，使 计划跟踪的培训环境，允许灵活地满足受训者的个人需求，并确保 在赛道上取得了成功的进展。该机构有强有力的实习生招聘计划。有几个是 针对代表性不足的少数族裔候选人。我们将继续提供量身定做的培训 每个候选人通过座谈会、研讨会、课程、临床研究中心和合作研究 在计划的各个轨道和所有轨道之间整合的活动。

Project Summary: This is a proposal for the continuation of the Institutional Training Program in Skeletal, Craniofacial and Oral Biology at the UConn Health, School of Dental Medicine as a T90/R90 program. It is intended to help meet the substantial need for independent scientists trained in research related to improving oral, dental and craniofacial health in the United States. The program has and will continue to train scholars (DMD and non-DMD) who are competent as clinicians and independent scientists, who are able to initiate and maintain funded research programs, who understand multidisciplinary research and who are prepared for the evolution of their research into new directions. Areas of research training include Tissue Engineering and Regenerative Medicine, Cell and Cancer Biology, Computational Biology, Genomics and Bioinformatics, Craniofacial and Skeletal Biology, Gene Regulation, Immunology, Microbiome/Microbiology, Oral Biology, Stem Cell Biology, and clinical and translational research. The major tracks of the training program are the (i) DMD/PhD (7-8 yrs of training with 3- 5 yrs of support from this training grant; 4 present trainees, 1-4 (depending on success of F30s) additional trainees requested over five yrs), (ii) PhD (4-5 yrs of training with 3 yrs of support; 3 present trainees, 6 additional trainees requested), (iii) postdoctoral research (3 yrs training and support; 3 present trainees, 5 additional trainees requested) and (iv) non-citizen PhD trainees (with DDS degrees) (3-5 yrs of training with 3 yrs of support; 1 present trainees 2 additional trainees requested). We will be training individuals with a broad range of backgrounds, from those with BS/BA degrees to those who have completed PhD and/or dental residency training. To provide a solid, common foundation for our scholars/trainees, we have developed Core Activities required of all trainees in all training tracks. We are introducing several new program features to (i) insure training milestones are achieved, (ii) facilitate preparation of F and K awards by trainees, (iii) better integrate clinical and research training for our DMD/PhDs to enhance transition into an academic career, and (iv) career development plans for teaching and laboratory management. UConn Health has a dynamic group of faculty in various areas of research with highly successful collaborations among faculty throughout the Schools of Dental Medicine and Medicine and The Jackson Laboratory for Genomic Medicine. The Biomedical Science PhD program graduate faculty, active and new institutional research centers and clinical programs provide contemporary laboratory, translational and patient oriented research opportunities that enable a diversified training environment for the program tracks, allow flexibility for the individual needs of trainees, and ensure successful progress through the tracks. The institution has vigorous trainee recruitment programs. Several are directed towards under-represented minority candidates. We will continue to provide training that is tailored to each candidate through symposia, seminars, courses, clinical research centers and collaborative research activities which are integrated both within individual tracks and amongst all the tracks of the program.