Skeletal, Craniofacial and Oral Biology Training Grant
骨骼、颅面和口腔生物学培训补助金
基本信息
- 批准号:10661130
- 负责人:
- 金额:--
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2011
- 资助国家:美国
- 起止时间:2011-07-01 至 2023-06-30
- 项目状态:已结题
- 来源:
- 关键词:AreaBioinformaticsBiologyCancer BiologyCellular biologyClinicalClinical ResearchCollaborationsComputational BiologyDentalDental ResidenciesDental SchoolsDevelopment PlansDoctor of PhilosophyEnsureEnvironmentEvolutionFacultyFoundationsFundingGene Expression RegulationGenomic medicineGenomicsGrantHealthImmunologyIndividualInstitutionInterdisciplinary StudyK-Series Research Career ProgramsLaboratoriesMedicineMicrobiologyOralPreparationRegenerative MedicineResearchResearch ActivityResearch TrainingScienceScientistSolidThe Jackson LaboratoryTissue EngineeringTrainingTraining ProgramsTraining SupportTranslational ResearchUnderrepresented MinorityUnited Statescareercareer developmentcraniofacialflexibilityimprovedmicrobiomeoral biologypatient oriented researchprogramsrecruitskeletalstem cell biologysuccesssymposiumteaching laboratory
项目摘要
Project Summary:
This is a proposal for the continuation of the Institutional Training Program in Skeletal, Craniofacial and Oral
Biology at the UConn Health, School of Dental Medicine as a T90/R90 program. It is intended to help meet the
substantial need for independent scientists trained in research related to improving oral, dental and craniofacial
health in the United States. The program has and will continue to train scholars (DMD and non-DMD) who are
competent as clinicians and independent scientists, who are able to initiate and maintain funded research
programs, who understand multidisciplinary research and who are prepared for the evolution of their research
into new directions. Areas of research training include Tissue Engineering and Regenerative Medicine, Cell
and Cancer Biology, Computational Biology, Genomics and Bioinformatics, Craniofacial and Skeletal Biology,
Gene Regulation, Immunology, Microbiome/Microbiology, Oral Biology, Stem Cell Biology, and clinical and
translational research. The major tracks of the training program are the (i) DMD/PhD (7-8 yrs of training with 3-
5 yrs of support from this training grant; 4 present trainees, 1-4 (depending on success of F30s) additional
trainees requested over five yrs), (ii) PhD (4-5 yrs of training with 3 yrs of support; 3 present trainees, 6
additional trainees requested), (iii) postdoctoral research (3 yrs training and support; 3 present trainees, 5
additional trainees requested) and (iv) non-citizen PhD trainees (with DDS degrees) (3-5 yrs of training with 3
yrs of support; 1 present trainees 2 additional trainees requested). We will be training individuals with a broad
range of backgrounds, from those with BS/BA degrees to those who have completed PhD and/or dental
residency training. To provide a solid, common foundation for our scholars/trainees, we have developed Core
Activities required of all trainees in all training tracks. We are introducing several new program features to (i)
insure training milestones are achieved, (ii) facilitate preparation of F and K awards by trainees, (iii) better
integrate clinical and research training for our DMD/PhDs to enhance transition into an academic career, and
(iv) career development plans for teaching and laboratory management. UConn Health has a dynamic group of
faculty in various areas of research with highly successful collaborations among faculty throughout the Schools
of Dental Medicine and Medicine and The Jackson Laboratory for Genomic Medicine. The Biomedical Science
PhD program graduate faculty, active and new institutional research centers and clinical programs provide
contemporary laboratory, translational and patient oriented research opportunities that enable a diversified
training environment for the program tracks, allow flexibility for the individual needs of trainees, and ensure
successful progress through the tracks. The institution has vigorous trainee recruitment programs. Several are
directed towards under-represented minority candidates. We will continue to provide training that is tailored to
each candidate through symposia, seminars, courses, clinical research centers and collaborative research
activities which are integrated both within individual tracks and amongst all the tracks of the program.
项目概要:
这是关于继续骨骼、颅面和口腔机构培训计划的提案
康涅狄格大学健康学院牙科医学院的生物学作为 T90/R90 项目。其目的是帮助满足
大量需要接受过与改善口腔、牙科和颅面相关研究培训的独立科学家
在美国的健康状况。该计划已经并将继续培训以下学者(DMD 和非 DMD):
有能力作为临床医生和独立科学家,能够启动和维持资助的研究
项目,了解多学科研究并为研究的发展做好准备
进入新的方向。研究培训领域包括组织工程和再生医学、细胞
和癌症生物学、计算生物学、基因组学和生物信息学、颅面和骨骼生物学、
基因调控、免疫学、微生物组/微生物学、口腔生物学、干细胞生物学以及临床和
转化研究。培训计划的主要轨道是 (i) DMD/PhD(7-8 年的培训,其中 3-
此培训补助金提供 5 年支持; 4 名现有学员,额外 1-4 名(取决于 F30 的成功情况)
受训者要求五年以上),(ii) 博士(4-5 年培训,3 年支持;3 名现任受训者,6 名)
要求增加学员),(iii) 博士后研究(3 年培训和支持;3 名现任学员,5 名)
要求额外的受训人员)和 (iv) 非公民博士受训人员(具有 DDS 学位)(3-5 年的培训,其中 3
多年的支持; 1 名现有学员 2 名要求额外学员)。我们将培训具有广泛知识的个人
各种背景,从拥有学士/文学学士学位的人到完成博士学位和/或牙科学位的人
住院医师培训。为了为我们的学者/学员提供坚实、共同的基础,我们开发了核心
所有培训课程中所有学员所需的活动。我们正在引入几项新的程序功能:(i)
确保实现培训里程碑,(ii) 促进受训人员准备 F 和 K 奖,(iii) 更好
整合我们的 DMD/PhD 的临床和研究培训,以促进向学术职业的过渡,以及
(iv) 教学和实验室管理的职业发展计划。康涅狄格大学健康中心拥有一支充满活力的团队
各个研究领域的教师与整个学院的教师之间的合作非常成功
牙科医学和医学系以及杰克逊基因组医学实验室。生物医学科学
博士项目的研究生教师、活跃的新机构研究中心和临床项目提供
当代实验室、转化和以患者为导向的研究机会,使多元化
项目轨道的培训环境,允许灵活地满足学员的个人需求,并确保
通过轨道取得成功。该机构制定了积极的实习生招募计划。有几个是
针对代表性不足的少数族裔候选人。我们将继续提供量身定制的培训
每位候选人通过座谈会、研讨会、课程、临床研究中心和合作研究
这些活动既集成在单个轨道中,也集成在计划的所有轨道中。
项目成果
期刊论文数量(41)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Regeneration of Articular Cartilage by Human ESC-Derived Mesenchymal Progenitors Treated Sequentially with BMP-2 and Wnt5a.
- DOI:10.5966/sctm.2016-0020
- 发表时间:2017-01
- 期刊:
- 影响因子:6
- 作者:Gibson JD;O'Sullivan MB;Alaee F;Paglia DN;Yoshida R;Guzzo RM;Drissi H
- 通讯作者:Drissi H
Inhibition of miR-29-3p isoforms via tough decoy suppresses osteoblast function in homeostasis but promotes intermittent parathyroid hormone-induced bone anabolism.
- DOI:10.1016/j.bone.2020.115779
- 发表时间:2021-03
- 期刊:
- 影响因子:4.1
- 作者:Hrdlicka HC;Pereira RC;Shin B;Yee SP;Deymier AC;Lee SK;Delany AM
- 通讯作者:Delany AM
MicroRNAs are Critical Regulators of Osteoclast Differentiation.
- DOI:10.1007/s40610-019-0116-3
- 发表时间:2019-02-01
- 期刊:
- 影响因子:0
- 作者:Hrdlicka, Henry C;Lee, Sun-Kyeong;Delany, Anne M
- 通讯作者:Delany, Anne M
Transcriptional profiling of neuronal ion channels in dorsal root ganglion-derived immortal cell line (F-11) under different culture conditions.
不同培养条件下背根神经节来源的永生细胞系(F-11)神经元离子通道的转录谱。
- DOI:10.1007/s44164-022-00036-7
- 发表时间:2022
- 期刊:
- 影响因子:0
- 作者:Morato,ErickOrozco;Knight,Brittany;Nair,LakshmiS
- 通讯作者:Nair,LakshmiS
Loss of Cbl-PI3K interaction modulates the periosteal response to fracture by enhancing osteogenic commitment and differentiation.
- DOI:10.1016/j.bone.2016.11.020
- 发表时间:2017-03
- 期刊:
- 影响因子:4.1
- 作者:Scanlon V;Walia B;Yu J;Hansen M;Drissi H;Maye P;Sanjay A
- 通讯作者:Sanjay A
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{{ truncateString('Mina Mina', 18)}}的其他基金
Skeletal, Craniofacial and Oral Biology Training Grant
骨骼、颅面和口腔生物学培训补助金
- 批准号:
10845816 - 财政年份:2023
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14th International Conference on the Chemistry and Biology of Mineralized Tissues (ICCBMT)
第14届国际矿化组织化学与生物学会议(ICCBMT)
- 批准号:
10682749 - 财政年份:2023
- 资助金额:
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Skeletal, Craniofacial and Oral Biology Training Grant
骨骼、颅面和口腔生物学培训补助金
- 批准号:
10711506 - 财政年份:2023
- 资助金额:
-- - 项目类别:
Investigating the roles of Hh signaling and Gli1+ cells in primary and reparative dentinogenesis in mouse molars
研究 Hh 信号传导和 Gli1 细胞在小鼠磨牙初级和修复性牙本质发生中的作用
- 批准号:
9767762 - 财政年份:2018
- 资助金额:
-- - 项目类别:
Skeletal, Craniofacial and Oral Biology Training Grant
骨骼、颅面和口腔生物学培训补助金
- 批准号:
8264596 - 财政年份:2011
- 资助金额:
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Skeletal, Craniofacial and Oral Biology Training Grant
骨骼、颅面和口腔生物学培训补助金
- 批准号:
8852480 - 财政年份:2011
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Skeletal, Craniofacial and Oral Biology Training Grant
骨骼、颅面和口腔生物学培训补助金
- 批准号:
8852479 - 财政年份:2011
- 资助金额:
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Skeletal, Craniofacial and Oral Biology Training Grant
骨骼、颅面和口腔生物学培训补助金
- 批准号:
8271258 - 财政年份:2011
- 资助金额:
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Skeletal, Craniofacial and Oral Biology Training Grant
骨骼、颅面和口腔生物学培训补助金
- 批准号:
8664247 - 财政年份:2011
- 资助金额:
-- - 项目类别:
Skeletal, Craniofacial and Oral Biology Training Grant
骨骼、颅面和口腔生物学培训补助金
- 批准号:
8499943 - 财政年份:2011
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