The Wilmer Institute Mentored Clinician Scientist Scholar Program

项目摘要/摘要 在续签申请中，Wilmer K12计划寻求继续其成功的招聘和 在高度相关的临床和实验室视力研究领域开发新的研究人员。我们的过去 记录表明，在对进入全职学术研究的年轻科学家进行指导培训方面取得了成功 并有效地竞争个人和合作赠款的支持。由于我们的声誉 临床医生-科学家培训和视觉科学主要研究领域的多样性 学者们，我们每年都会为Wilmer K12项目吸引多名极具吸引力的候选人。我们的 结构化的计划仍然保留了相当大的灵活性，可以利用多个导师小组进行培训 在说教和实践活动的结合中。部门执行委员会的存在 对每个获奖者(K12、K08和K23)的持续监督确保每个获奖者都得到最新信息 审查他们的计划，纠正运行不理想的领域。具体的时间表和 严格执行每个K学者项目的指导方针。我们的进度报告显示， Wilmer K12毕业生向独立研究职业发展和R级资助远远高于 已发布的国家标准。37名科学家的教职员工参与表明了这一点，其中许多人是K 获奖者本身，机构专业知识和对该计划的承诺是该计划的高度优先事项 威尔默研究所。K12参与学院的综合研究补助金包括总的直接成本。 今年超过3000万美元。这确保了有足够的资金来支持被指导的成本 K奖项本身不包括的培训。威尔默培养了更多的全职学者和 系主任比美国任何其他眼科研究所或系都要多。此外，每个 威尔默的K12/K08/K23学者受益于导师团队，不仅包括眼科教员，还包括 来自约翰·霍普金斯大学约翰·霍普金斯医学院其他系的科学家 应用物理实验室和彭博公共卫生学院。这些合作使交叉受精 学者培训和研究所的研究环境，并包括 神经科学、医学、生物医学工程、流行病学、国际卫生、 和计算机科学。执行委员会保持警惕，以确保导师和学员都是 履行其职责，定期进行书面评估。执行委员会由以下成员组成 经验丰富和多样化的视觉科学家，其中一些人最近正在接受K培训，另一些人已经 多年来，曾指导过多名K学者。联合项目主任奎格利博士已经指导了50多名 临床医生-科学家，包括十几个机构的科室主任和科室主任 国内和国际上。另一位联合项目主任汉达博士是一位杰出的临床医生和科学家 在持续不断的实验室资助下，最近担任NIH视觉科学研究部门的主席 获奖者，并有多位过去的K导师。Wilmer的临床和实验室研究设施包括 无与伦比的，包括20万平方英尺的史密斯大厦。

Project Summary/Abstract In its renewal application, the Wilmer K12 Program seeks to continue its successful recruitment and development of new investigators in highly relevant areas of clinical and laboratory vision research. Our past track record indicates success in mentored training of young scientists who enter full-time academic research careers and compete effectively for individual and collaborative grant support. Due to our reputation for clinician—scientist training and the diversity of major research areas in vision science that are available to scholars, we have every year attracted multiple highly attractive candidates for the Wilmer K12 program. Our structured program still leaves considerable flexibility to take advantage of multiple—mentor groups for training in a combination of didactic and practical activities. The existence of a Departmental executive committee for ongoing oversight of every K awardee (K12, K08 and K23) assures that each scholar will be given updated review of their program and correction of areas that are not functioning ideally. Specific timelines and guidelines for following of each K scholar program are strictly enforced. Our progress report shows that the progression to independent research careers and R level funding for Wilmer K12 graduates is far above the national standard as published. As shown by the faculty involvement of 37 scientists, many of whom were K awardees themselves, the institutional expertise and commitment to this program is a high priority of the Wilmer Institute. The combined research grants of the K12 participating faculty comprises a total direct cost this year of over $30 million. This ensures that adequate funding is available to support the costs of mentored training that are not covered by the K awards themselves. Wilmer has produced more full time academics and Department Chairpersons than any other eye institute or department in the U.S. Furthermore, each K12/K08/K23 scholar at Wilmer benefits from a mentor team than includes not only Ophthalmology faculty, but scientists from other departments at the Johns Hopkins School of Medicine, Johns Hopkins University, the Applied Physics Laboratory, and the Bloomberg School of Public Health. These collaborations cross-fertilize both scholar training and the research environment of the Institute, and have included members of Departments such as Neuroscience, Medicine, Biomedical Engineering, Epidemiology, International Health, and Computer Science. The Executive Committee is vigilant to assure that the mentors and mentees are both fulfilling their roles, with written evaluations at regular intervals. The Executive Committee consists of experienced and diverse vision scientists, some of whom recently were in K training and others who have over many years mentored multiple K scholars. The co-Program Director, Dr. Quigley, has mentored over 50 clinician—scientists, including Department Chairs and Division Directors in more than a dozen institutions nationally and internationally. The other co-Program Director, Dr. Handa, is a distinguished clinician—scientist with continuous laboratory funding, recently the Chair of a visual sciences NIH study section, past K11 awardee, and with multiple past K mentees.The facilities of Wilmer's clinical and lab research are unsurpassed, including the 200,000 square foot Smith Building.