Behavioral Neuroscience Research Core

项目摘要：行为神经科学核心 行为神经科学(BN)核心将支持认知和 可塑性的神经生物学方法(CNAP)中心通过提供资源、设备和 为增强CNAP主要项目和计划的研究能力提供技术支持。国阵核心， 位于堪萨斯州立大学心理科学系内的是唯一专门的BN 堪萨斯州心理学核心。在第二阶段，国阵核心设施将进行现代化改造和扩充 通过增加主要设备项目来扩大设施的能力，并提供额外的 技术支持。国阵核心将直接支持拟议的第二阶段主要项目中的两个(Diehl和 霍尔)、试点赠款和科学交流网络(SEN)方案，以及目前的用户社区 行为神经科学项目。拟议的设施现代化将促进 行为神经科学进入令人兴奋和创新的研究领域，纳入最先进的研究 这些技术将改善K-State动物神经科学研究的研究基础设施。升级 将允许BN Core将细胞外电生理记录与光遗传学相结合引入 研究计划，并将增加对一系列生化分析、荧光显微镜和 设计师受体仅由设计师药物(DREADD)激活。核心设施的扩建将 同时，通过为特殊教育合作伙伴提供良好的培训环境来支持CNAP计划。《核心》 总监和核心技术人员将为CNAP提供神经科学和行为技术方面的专业知识 核心设施外有实验室的成员。国阵核心的全面目标是 通过采用以下技术促进CNAP研究人员竞争外部资金的能力 是回答现代神经科学研究人员面临的最具挑战性的问题所必需的。核心是 由查尔斯·皮肯斯博士指导，他是一位全国知名的行为神经科学研究人员，研究 动物模型中的决策。CNAP辅导将提供额外的培训和辅导 小组成员、外部咨询委员会成员和K-State国阵协作网络成员。一个 全职动物护理技术员将提供日常设施清洁和维护，并将满足动物 设施使用者的护理和饲养需求。总体而言，国阵核心将支持实现国家行动计划 主要目标是促进认知和神经可塑性动物模型的成功和发展， CNAP的核心组成部分。

PROJECT SUMMARY: BEHAVIORAL NEUROSCIENCE CORE The Behavioral Neuroscience (BN) Core will support the overarching goals of the Cognitive and Neurobiological Approaches to Plasticity (CNAP) Center through the provision of resources, equipment, and technical support to enhance the research capabilities of CNAP primary projects and programs. The BN Core, housed within the Department of Psychological Sciences at Kansas State University, is the only dedicated BN core in Psychology in the state of Kansas. In Phase 2, the BN Core facility will be modernized and augmented through the addition of major equipment items to expand the capabilities of the facility and provide additional technical support. The BN Core will directly support two of the proposed Phase 2 primary projects (Diehl and Hall), the pilot grant and Scientific Exchange Network (SEN) programs, and the current community of users in the behavioral neuroscience program. The proposed modernization of the facility will promote the growth of behavioral neuroscience into exciting and innovative research areas that incorporate state-of-the-art techniques that will improve the research infrastructure for animal neuroscience research at K-State. Upgrades will allow the BN Core to introduce extracellular electrophysiological recordings coupled with optogenetics into research programs and will increase support for a range of biochemical assays, fluorescence microscopy, and Designer Receptors Exclusively Activated by Designer Drugs (DREADDs). The expansion of core facilities will also support CNAP programs by providing an excellent training environment for SEN partners. The Core Director and Core Technician will supply expertise in neuroscience and behavioral techniques to CNAP members with laboratories housed outside of the core facility. The comprehensive goal of the BN Core is to promote the ability of CNAP researchers to compete for extramural funding by incorporating technologies that are needed to answer the most challenging questions facing modern neuroscience researchers. The core is directed by Dr. Charles Pickens, a nationally known researcher in behavioral neuroscience in neural circuits of decision-making in animal models. Additional training and mentoring will be supplied by the CNAP mentoring team, External Advisory Committee members, and members from the BN collaborative network at K-State. A full-time Animal Care Technician will provide daily facility cleaning and maintenance and will meet the animal care and husbandry needs of facility users. Overall, the BN Core will support the attainment of the CNAP overarching aims by contributing to the success and growth of animal models of cognitive and neural plasticity, a central component of CNAP.