PROJECT 1

项目1

• 批准号: 10661347
• 负责人: Erica Phillips
• 金额: $ 38.14万
• 依托单位: WEILL MEDICAL COLL OF CORNELL UNIV
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-05-31 至 2028-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10661347
• 关键词: Address; Adherence; Adolescent; Adult; Age; Behavior; Behavioral; Beverages; Black race; Cancer Burden; Cancer Control Research; Caregivers; Characteristics; Child; Cities; Collaborations; Communication; Country; Data; Disparity; Education; Educational Curriculum; Educational Intervention; Educational process of instructing; Ethnic Origin; Exposure to; Failure; Family; Family member; Fellowship; Future; Goals; Health; Health Promotion; Hispanic; Home; Household; Incidence; Individual; Intention; Intervention; Intervention Studies; Interview; Knowledge; Life Cycle Stages; Life Style; Low income; Malignant Neoplasms; Malignant neoplasm of cervix uteri; Marketing; Mathematics; Modeling; Neighborhoods; New York City; Nonprofit Organizations; Outcome Measure; Parents; Personal Satisfaction; Population Study; Poverty; Poverty Areas; Preparation; Prevention program; Randomized; Research; Resources; Rest; Risk Behaviors; Risk Factors; Schools; Self Determination; Social Change; Social Justice; Specific qualifier value; Stress; Students; System; Testing; Training; Training Programs; Unemployment; United States; Vulnerable Populations; Waiting Lists; Youth; active control group; behavior change; built environment; cancer education; cancer health disparity; cancer initiation; cancer prevention; cancer risk; design; effectiveness testing; empowerment; ethnic minority; experience; follow-up; improved; innovation; junior high school; lens; post intervention; primary outcome; programs; racial minority; residence; response; rural counties; science teacher; secondary outcome; social capital; social consciousness; social culture; teacher; theories; therapy design; young adult

The rise in cancer incidence among younger adults (ages 20-39) in NYC is currently outpacing the increase across the rest of the US (96.9 vs. 89.5 per 100,000). However, the burden of cancer in NYC is not equally distributed. In NYC's poorest neighborhoods, the rates of preventable cancers, such as cervical cancer, is 73% higher compared to the wealthiest neighborhoods. The magnitude of this disparity exceeds those associated with Black race, Hispanic ethnicity, or residence in a rural county documented in a previous population-based study of the US. Rather, it is likely the persistent poverty in these neighborhoods that drives cancer disparities. Despite these known facts, there remains limited research on multi-level and multi-generational approaches that address the impact of persistent poverty on youth and young adults' current and future cancer risk behaviors. Effective cancer education interventions in schools could significantly impact health-promoting intentions and cancer risk behaviors in younger adults. To date, most school-based intervention studies have been limited. The need for this research is especially salient in NYC, the most populous city in the United States, with nearly 2 million New Yorkers under 18. In response to RFA-CA-22-015 Cancer Control Research in Persistent Poverty Areas, this application in randomize a total of 10 new York City schools (n=906 students) in two waves, over 2 years, to an immediate vs delayed (wait list control) six-week cancer education and social justice intervention delivered by trained classroom science teachers. The intervention is guided by the Self-Determination and youth empowerment theory, thus it will leverage the natural desire of youth to be socially conscious, autonomous individuals who can be effective agents of social change. The intervention aims to: 1) increase students’ intention to engage in at least one health-promoting behavior (e.g., drink less or no sugary beverages) in the next month as a predictor of actual behavior change; and 2) increase cancer risk communication between the student and a parent. Additionally, we will explore the impact of increased cancer risk communication on the health-promoting behaviors of at least one parent or adult caregiver in the household. Assessments of students will be conducted at baseline, 6 and 24 weeks. Parents will be assessed 6 weeks after implementation of the curricula and then again at 24 weeks. If effective, our pragmatic approach provides a framework for integrating a cancer education intervention with a social justice lens more broadly into NYC public schools, the largest public school system in the country. This program will have far-reaching effects, empowering adolescents with knowledge that can not only mitigate future cancer incidence of vulnerable youth but also promote healthier behaviors within families.

纽约市年轻人（20-39 岁）癌症发病率的上升速度目前超过了 美国其他地区（每 10 万人中 96.9 人 vs. 89.5 人）。然而，纽约市的癌症负担并不相同 分布式。在纽约市最贫困的社区，宫颈癌等可预防癌症的发病率为 73% 与最富裕的社区相比更高。这种差异的幅度超过了相关的差异 具有黑人种族、西班牙裔种族或居住在先前基于人口的人口记录中记录的农村县 研究美国。相反，这些社区的持续贫困很可能导致了癌症差异。 尽管有这些已知的事实，但对多层次和多代方法的研究仍然有限。 解决持续贫困对青少年当前和未来癌症风险行为的影响。 学校有效的癌症教育干预措施可以显着影响健康促进意图和 年轻人的癌症风险行为。迄今为止，大多数以学校为基础的干预研究都是有限的。这 在美国人口最多的城市纽约市，这项研究的需求尤为突出，有近 2 百万 18 岁以下纽约人。回应 RFA-CA-22-015 持续贫困中的癌症控制研究 地区，此应用程序将总共 10 所纽约市学校（n = 906 名学生）随机分为两波，超过 2 年，立即与延迟（等待名单控制）六周的癌症教育和社会正义干预 由经过培训的课堂科学教师授课。干预以自决和青年为指导 赋权理论，因此它将利用年轻人具有社会意识、自主性的自然愿望 可以成为社会变革的有效推动者的个人。干预的目的是：1）提高学生的意愿 在下个月从事至少一种促进健康的行为（例如少喝或不喝含糖饮料） 作为实际行为变化的预测因子； 2) 增加学生和学生之间的癌症风险沟通 一位家长。此外，我们将探讨增加癌症风险沟通对健康促进的影响 家庭中至少一位父母或成年照顾者的行为。将对学生进行评估 基线、第 6 周和第 24 周。课程实施后 6 周将对家长进行评估，然后 24周时再次进行。如果有效，我们的务实方法将为整合癌症提供一个框架 从社会正义的角度更广泛地对纽约市公立学校（最大的公立学校）进行教育干预 国内的制度。该计划将产生深远影响，让青少年获得知识 这不仅可以降低弱势青少年未来的癌症发病率，还可以促进更健康的行为 家庭内部。