Radiochemistry Capacity/Capability Development Expansion of Alpha or Beta Radionuclide Testing Capabilities

放射化学能力/能力发展 α 或 β 放射性核素测试能力的扩展

• 批准号: 10670060
• 负责人: Katelyn Jean Stewart Hoke
• 金额: $ 24.81万
• 依托单位: ILLINOIS STATE EMERGENCY MANAGEMENT AGENCY
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-01 至 2025-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10670060
• 关键词: Radiochemistry; Capacity; Capability; Development; Expansion

SUMMARY (Overall) One of the Illinois Emergency Management Agency’s (IEMA) long term objectives is to strengthen the Agency’s collaboration with the FDA. It is hoped that this collaboration will allow IEMA to develop and enhance its radiological analyses of food capability while contributing to the national effort. In the event of a large scale nuclear or radiological incident, a high load of food samples will need to be analyzed and reported rapidly and accurately (Cunningham 2014). The food sample radiological results can then be used to help officials make well informed decisions/actions to protect public health (EPA 2017). It is IEMA’s objective to ready the Radiochemistry laboratory for just such an event. The laboratory is currently equipped and prepared for the analysis of foods for gamma emitting radionuclides. However, we lack the experience to screen foods for alpha and/or beta emitters and the Agency’s current liquid scintillation counters are at, or close to, the end of their serviceable life. IEMA is thus seeking support through this radiochemistry analytical development opportunity in conjunction with the FDA’s scientific expertise to assist in developing the Agency’s capability to screen foods for alpha and/or beta emitters. If the Agency is awarded this opportunity, collaboration with the FDA will be enhanced, through training and a face-to-face meetings. When completed, the Radiochemistry laboratory will demonstrate competency for screening alpha and/or beta emitters and will be ready for the call to participate in radiological national security exercises, surveillance testing activities and radiological incidents. As a member of the Food Emergency Response Network, the IEMA Radiochemistry laboratory proposes to expand the national alpha and beta analysis capacity though its request to purchase a PerkinElmer Quantulus GCT LSC 6220TR low activity liquid scintillation counter which includes alpha/beta discrimination software (PerkinElmer 2020). Within the one year project time, the Agency will procure, install, set-up and calibrate the instrument. The staff will train on the FDA selected method(s) in the analysis of food for alpha and beta- emitters using liquid scintillation counting. The method(s) will be validated followed by the successfully demonstration of competency in the validated method(s). IEMA management will support travel to send a selected staff members to attend the annual Laboratory Flexible Funding Model Face-to Face meeting. The project aims will be accomplished through Management’s emphasis on successfully expanding our radiological rapid emergency response analysis of foods, especially for non-gamma emitting radionuclides. This proposal is supported by the strength of the Radiochemistry laboratory’s staff experience and education and the availability of the newly remodeled and equipped wet chemistry laboratory. As noted above it is IEMA’s goal to be ready for the call to participate in radiological national security exercises, surveillance testing activities and radiological incidents.

摘要（总体） 伊利诺伊州应急管理局 (IEMA) 的长期目标之一是加强 该机构与 FDA 的合作。希望此次合作能够让 IEMA 发展和增强 它对粮食能力进行放射性分析，同时为国家努力做出贡献。如果发生大规模 核或放射性事件，需要快速分析和报告大量食品样本， 准确地（Cunningham 2014）。食品样本的放射性结果可用于帮助官员制定 保护公众健康的明智决策/行动（EPA 2017）。 IEMA 的目标是为 放射化学实验室就专门举办了这样的活动。目前，实验室已具备相应的设备和准备 分析食品中的伽马发射放射性核素。然而，我们缺乏筛选食品的经验 α和/或β发射器以及原子能机构目前的液体闪烁计数器已处于或接近年底 他们的使用寿命。因此，IEMA 正在通过放射化学分析开发寻求支持 与 FDA 的科学专业知识相结合的机会，以协助发展该机构的能力 筛选食物中的α和/或β发射体。如果该机构获得此机会，则与 FDA 将通过培训和面对面会议得到加强。完成后，放射化学 实验室将展示筛选 α 和/或 β 发射体的能力，并为通话做好准备 参加放射国家安全演习、监视检测活动和放射事件。 作为食品应急响应网络的成员，IEMA 放射化学实验室建议： 通过请求购买 PerkinElmer Quantulus 扩大国家 alpha 和 beta 分析能力 GCT LSC 6220TR 低活度液体闪烁计数器，包括 α/β 辨别软件 （珀金埃尔默 2020）。在一年的项目时间内，该机构将采购、安装、设置和校准 乐器。工作人员将接受 FDA 选择的食品 α 和 β 分析方法培训 使用液体闪烁计数的发射器。该方法将被验证，然后成功 证明经过验证的方法的能力。 IEMA 管理层将支持差旅人员发送 选派工作人员参加年度实验室灵活资助模式面对面会议。这 项目目标将通过管理层强调成功扩大我们的放射学业务来实现 食品的快速应急响应分析，特别是非伽马发射放射性核素。这个提议是 放射化学实验室的工作人员经验和教育以及 新改建和装备的湿化学实验室的可用性。如上所述，IEMA 的目标是 准备好参加放射国家安全演习、监视测试活动和 放射性事件。