Pilot/Exploratory Studies Core (PESC)

试点/探索性研究核心（PESC）

• 批准号: 10670210
• 负责人: Mary McGrae McDermott
• 金额: $ 29.52万
• 依托单位: NORTHWESTERN UNIVERSITY AT CHICAGO
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-08-01 至 2025-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10670210
• 关键词: Accident and Emergency department; Advisory Committees; Aging; American; Applications Grants; Applied Research; Award; Back; Capsicum; Caregivers; Caring; Chicago; Clinical; Clinical Sciences; Communication; Communities; Complex; Data; Depressed mood; Development; Direct Costs; Elderly; Electronics; Emergency Care; Emergency Medicine; Faculty; Foundations; Funding; Future; Geriatrics; Goals; Grant; Health; Industry; Information Dissemination; Institution; Intervention; Lead; Leadership; Life Cycle Stages; Link; Managed Care; Manuscripts; Measurement; Medical; Medication Errors; Mental Depression; Mentors; Methodology; Modeling; Monitor; Patients; Peer Review; Pharmaceutical Preparations; Pharmacotherapy; Pilot Projects; Primary Care; Process; Publishing; Quality of life; Readiness; Recommendation; Request for Applications; Research; Research Design; Research Personnel; Research Project Grants; Resources; Services; Skilled Nursing Facilities; Stream; Study Section; System; Training; Translational Research; United States National Institutes of Health; Universities; Voice; Work; career; community involvement; design; education research; expectation; experience; faculty support; functional improvement; functional outcomes; hospital readmission; improved; innovation; intelligent personal assistant; interest; meetings; member; multidisciplinary; multiple chronic conditions; novel; pilot test; primary care practice; primary care services; professor; programs; psychologic; tool

ABSTRACT The overarching goal of the Northwestern Older Americans Independence Center (OAIC, a.k.a. `Pepper Center') is to generate innovative research to enhance primary care for medically complex, older adults with multiple chronic conditions (MCC) to achieve optimal health, independence, and quality of life. The Pilot/Exploratory Studies Core (PESC) will be strategically linked to the Research Education Component (REC), to i) identify, select, and fund junior faculty, `Pepper Scholar' trainees with aging interests related to MCC; ii) mentor, support and monitor Scholars through a formidable research project that will provide them with sufficient preliminary data to help justify larger, independent grant proposals and successfully advance their career. The specific aims of the PESC are to: Aim 1 Fund, initiate, and conduct a first wave of Pilot/Exploratory Studies (PES 1-3) that will engage junior investigators in Northwestern's OAIC research enterprise and generate innovative research designed to improve function and quality of life for older Americans with MCC. Aim 2 Implement a process by which the Northwestern OAIC will solicit, peer-review, select and prioritize, support, and monitor at least 9 PES in the first 5 years of the Northwestern OAIC. Aim 3 Encourage the development of competitive, external grant applications leveraging Pepper Scholar PES and others doing related work at Northwestern, in Chicago and throughout the OAIC Network. Our Northwestern OAIC will award three waves of PES funding in Years 1-3 (minimum 9 awards, at least 3 per year); Center leadership held a competitive solicitation for pilot projects and have identified the 1st wave of Pepper Scholar PES: 1) Improving Transitions of Care from Skilled Nursing Facilities to the Community (Dr. Theresa Rowe, Assistant Professor, Geriatrics); 2) Intelligent Personal Assistant Depression Management for Homebound Older Adults ((Dr. Katherine O'Brien, Assistant Professor, Geriatrics); 3) An Emergency Department -based Deprescribing Intervention for Older Adults with MCC (Dr. Howard Kim, Assistant Professor, Emergency Medicine). The PESC will leverage processes and systems developed by the Northwestern University Clinical and Translational Sciences Institute (NUCATS) to manage PES competitions in Years 2 and 3; projects receive up to $100,000 direct costs over 2 years with in-kind methodological support from our OAIC Resource Cores (Design, Measurement, Analytics). Our trainee `pipeline' now extends to other academic institutions (UIC, Rush). Our Information Dissemination Core will also aid Pepper Scholars in widely disseminating PES findings.

抽象的 西北老年美国人独立的总体目标 中心（OAIC，又名“胡椒中心”）旨在开展创新研究 加强对病情复杂、患有多种慢性病的老年人的初级保健 条件（MCC）以实现最佳的健康、独立和生活质量。 试点/探索性研究核心（PESC）将与 研究教育部分 (REC)，i) 识别、选择和资助初级学生 教师、“胡椒学者”学员，对与 MCC 相关的老龄化兴趣； ii) 导师， 通过一个强大的研究项目来支持和监督学者，该项目将 为他们提供足够的初步数据，以帮助证明更大的、独立的 批准提案并成功推进他们的职业生涯。 PESC 的具体目标是： 目标 1 资助、启动并进行第一波试点/探索性研究 (PES 1-3)，让初级人员参与其中 西北大学 OAIC 研究企业的研究人员并进行创新研究设计 改善患有 MCC 的美国老年人的功能和生活质量。 目标 2 实施西北 OAIC 征求、同行评审、选择和优先排序的流程， 在西北 OAIC 的前 5 年中支持和监控至少 9 个 PES。 目标 3 鼓励利用 Pepper Scholar 开发有竞争力的外部资助申请 PES 和其他人在西北大学、芝加哥和整个 OAIC 网络从事相关工作。 我们的西北大学 OAIC 将在第 1-3 年授予三批 PES 资助（至少 9 项，每项至少 3 项） 年）;中心领导层举行了试点项目竞争性征集，并确定了第一波 Pepper 学者 PES：1) 改善从熟练护理机构到社区的护理过渡（Theresa 博士 Rowe，老年病学助理教授）； 2) 智能个人助理抑郁症管理 居家老年人（（Katherine O'Brien 博士，老年病学助理教授）；3）急诊科 针对患有 MCC 的老年人的基于去处方干预（Howard Kim 博士，急诊科助理教授） 药品）。 PESC 将利用西北大学临床中心开发的流程和系统 和转化科学研究所 (NUCATS) 管理第二年和第三年的 PES 竞赛；项目收到 两年内直接成本高达 100,000 美元，并获得我们的 OAIC 资源核心的实物方法支持 （设计、测量、分析）。我们的实习生“管道”现已延伸至其他学术机构（UIC、Rush）。 我们的信息传播核心还将帮助 Pepper Scholars 广泛传播 PES 研究结果。