Pilot/Exploratory Studies Core (PESC)

摘要 西北老年美国人独立的首要目标 中心（OAIC，又名“胡椒中心”）是为了进行创新研究， 加强对医学上复杂的老年人的初级保健， 条件（MCC），以实现最佳的健康，独立性和生活质量。 试点/探索性研究核心（PESC）将与 研究教育部分（REC），i）识别，选择和资助初级 教师，“胡椒学者”学员与老龄化的利益有关的MCC;二）导师， 通过一个强大的研究项目支持和监测学者， 为他们提供足够的初步数据，以帮助证明更大的，独立的， 批准提案并成功推进其职业生涯。 该委员会的具体目标是： 目标1资助、发起和开展第一波试点/探索性研究（PES 1-3）， 研究人员在西北的OAIC研究企业，并产生创新的研究设计 改善老年MCC患者的功能和生活质量。 目标2实施一个过程，西北OAIC将征求，同行评审，选择和优先考虑， 支持，并在西北OAIC的前5年监测至少9个PES。 目标3鼓励利用Pepper Scholar开发有竞争力的外部赠款申请 PES和其他在西北大学、芝加哥和整个OAIC网络做相关工作的人。 我们的西北OAIC将在第1-3年授予三波PES资金（最少9个奖项，每个奖项至少3个）。 年）;中心领导举行了试点项目的竞争性征集，并确定了第一波胡椒 学者PES：1）改善从专业护理设施到社区的护理过渡（Theresa博士 罗，助理教授，老年医学）; 2）智能个人助理抑郁症管理， 无家可归的老年人（（凯瑟琳奥布莱恩博士，老年医学助理教授）; 3）急诊科 老年MCC患者的基于处方的干预（霍华德金博士，急诊科助理教授， 医学）。PESC将利用西北大学临床研究所开发的流程和系统 和转化科学研究所（NUCATS）管理PES比赛在第二年和第三年;项目收到 在我们的OAIC资源核心的实物方法支持下，2年内直接成本高达100，000美元 （设计，测量，分析）。我们的受训人员“管道”现在延伸到其他学术机构（国际学院、拉什）。 我们的信息传播核心也将帮助胡椒学者广泛传播PES的研究结果。

ABSTRACT The overarching goal of the Northwestern Older Americans Independence Center (OAIC, a.k.a. `Pepper Center') is to generate innovative research to enhance primary care for medically complex, older adults with multiple chronic conditions (MCC) to achieve optimal health, independence, and quality of life. The Pilot/Exploratory Studies Core (PESC) will be strategically linked to the Research Education Component (REC), to i) identify, select, and fund junior faculty, `Pepper Scholar' trainees with aging interests related to MCC; ii) mentor, support and monitor Scholars through a formidable research project that will provide them with sufficient preliminary data to help justify larger, independent grant proposals and successfully advance their career. The specific aims of the PESC are to: Aim 1 Fund, initiate, and conduct a first wave of Pilot/Exploratory Studies (PES 1-3) that will engage junior investigators in Northwestern's OAIC research enterprise and generate innovative research designed to improve function and quality of life for older Americans with MCC. Aim 2 Implement a process by which the Northwestern OAIC will solicit, peer-review, select and prioritize, support, and monitor at least 9 PES in the first 5 years of the Northwestern OAIC. Aim 3 Encourage the development of competitive, external grant applications leveraging Pepper Scholar PES and others doing related work at Northwestern, in Chicago and throughout the OAIC Network. Our Northwestern OAIC will award three waves of PES funding in Years 1-3 (minimum 9 awards, at least 3 per year); Center leadership held a competitive solicitation for pilot projects and have identified the 1st wave of Pepper Scholar PES: 1) Improving Transitions of Care from Skilled Nursing Facilities to the Community (Dr. Theresa Rowe, Assistant Professor, Geriatrics); 2) Intelligent Personal Assistant Depression Management for Homebound Older Adults ((Dr. Katherine O'Brien, Assistant Professor, Geriatrics); 3) An Emergency Department -based Deprescribing Intervention for Older Adults with MCC (Dr. Howard Kim, Assistant Professor, Emergency Medicine). The PESC will leverage processes and systems developed by the Northwestern University Clinical and Translational Sciences Institute (NUCATS) to manage PES competitions in Years 2 and 3; projects receive up to $100,000 direct costs over 2 years with in-kind methodological support from our OAIC Resource Cores (Design, Measurement, Analytics). Our trainee `pipeline' now extends to other academic institutions (UIC, Rush). Our Information Dissemination Core will also aid Pepper Scholars in widely disseminating PES findings.