Research Education Core

研究教育核心

• 批准号: 10684071
• 负责人: Gene Gabriel Gurkoff
• 金额: $ 13.6万
• 依托单位: UNIVERSITY OF CALIFORNIA AT DAVIS
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-09-01 至 2027-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10684071
• 关键词: Academia; Acute; Address; Animal Disease Models; Area; Basic Science; Biometry; Chronic; Clinical Trials; Communities; Complex; Development; Diverse Workforce; Drug Screening; Educational Activities; Educational workshop; Effectiveness; Emergency response; Environment; Evaluation; Exposure to; Faculty; Feedback; Fostering; Future; Generations; Goals; Government; Growth; Human Resources; Image; Industry; Innovative Therapy; Institution; Interdisciplinary Study; Intoxication; Knowledge; Laboratories; Learning; Medical Students; Mentors; Mission; Neurologic; Neurology; Neurosciences; Organophosphates; Outcome; Participant; Patients; Pharmaceutical Chemistry; Pharmacology; Pharmacology and Toxicology; Postdoctoral Fellow; Preclinical Testing; Process; Research; Research Activity; Research Personnel; Research Project Summaries; Research Training; Resources; Scientist; Therapeutic; Toxicology; Training; Translational Research; Underrepresented Populations; United States National Institutes of Health; Work; career; chemical threat; cohort; design; disadvantaged background; drug development; drug discovery; education research; effectiveness evaluation; emergency preparedness; equity, diversity, and inclusion; experience; graduate student; improved; instructor; lectures; medical countermeasure; meetings; member; nervous system disorder; neurotoxicology; next generation; outreach; programs; recruit; responsible research conduct; role model; skills; socioeconomic disadvantage; success; undergraduate student

Project Summary – Research Education Core (REC) The training of future leaders in the development of medical countermeasures for chemical threat agents is critical to the success of the CounterACT program and to national emergency response and preparedness efforts. The overall mission of the Research Education Core (REC) is to create a diverse array of human resources capable of conducting team-based interdisciplinary research focused on addressing the complex problems posed by chemical threat agents. Advanced training in pharmacology, toxicology, neuroscience, and drug discovery will be provided to a diverse generation of researchers, more specifically, technicians, medical and graduate students, postdoctoral fellows, and/or early stage investigators within and outside the UC Davis CounterACT Center. Accordingly, the REC will interact with all Cores and Projects of the Center. A major emphasis will be enhancing the diversity, and recruitment of trainees and mentors from underrepresented and socioeconomically disadvantaged backgrounds into the Center. The educational research environment at UC Davis is well suited for the CounterACT Center. UC Davis is a national leader in pharmacology and toxicology, and CounterACT faculty have expertise in fundamental pharmacology, toxicology, medicinal chemistry, drug screening, mechanistic target identification, animal models of disease, advanced imaging, biostatistics as well as preclinical testing and participation in clinical trials. The REC will facilitate the transfer of this knowledge to trainees and promote the advancement of trainees’ careers by providing opportunities to be mentored by and learn from both internal and external scientists with expertise relevant to the CounterACT mission. The REC has three main objectives: (1) Develop skill sets necessary for the study of toxicology, pharmacology, drug discovery, neuroscience, and neurological disorders related to chemical threat agents. First, hands- on interdisciplinary and collaborative research training primarily in the laboratories of the Project and Core Leaders will be provided. Second, specialized didactic training in areas relevant to the Center’s mission will be accomplished via workshops, seminars, and specialized coursework. (2) Enhance the recruitment of graduate students and faculty from underrepresented backgrounds into the UC Davis CounterACT Center by leveraging well established undergraduate, graduate, and faculty STEM-related recruiting and retention programs on campus. (3) Evaluate the activities of the REC to assess effectiveness and identify areas for improvement. By fulfilling these objectives, the REC will accomplish its goal of developing a diverse group of scientists with broader understanding of the concepts, challenges, and opportunities in drug discovery and development of medical countermeasures of chemical threat agents.

项目摘要-研究教育核心（REC） 培养未来的领导者，制定针对化学威胁剂的医疗对策， 这对反ACT计划的成功以及国家应急响应和准备至关重要 努力研究教育核心（REC）的总体使命是创造一个多样化的人类 资源能够进行基于团队的跨学科研究，重点是解决复杂的 化学威胁剂带来的问题。药理学、毒理学、神经科学和 药物发现将提供给不同一代的研究人员，更具体地说，技术人员，医疗 研究生，博士后研究员和/或加州大学戴维斯分校内外的早期研究人员 反ACT中心。因此，REC将与中心的所有核心和项目进行互动。一个主要 重点将是加强多样性，从代表性不足的国家和地区征聘受训人员和导师， 社会经济背景的弱势群体进入中心。 加州大学戴维斯分校的教育研究环境非常适合反ACT中心。加州大学戴维斯分校是一个 药理学和毒理学的国家领导者，以及CounterACT教师在基础方面的专业知识 药理学、毒理学、药物化学、药物筛选、机制靶点鉴定、动物模型 疾病、先进成像、生物统计学以及临床前测试和参与临床试验。的 资源中心将协助学员学习这些知识，并促进学员的职业发展 通过提供机会，接受内部和外部具有专业知识的科学家的指导和学习， 与反恐行动使命有关 REC有三个主要目标：（1）发展毒理学，药理学， 药物发现、神经科学和与化学威胁剂有关的神经系统疾病。首先，手- 主要在项目和核心实验室进行跨学科和合作研究培训 将提供领导人。第二，在与中心的使命有关的领域进行专门的教学培训， 通过讲习班、研讨会和专业课程完成。(2)加强毕业生招聘 来自代表性不足背景的学生和教师进入加州大学戴维斯分校CounterACT中心， 完善的本科生，研究生和教师STEM相关的招聘和保留计划， 校园(3)评估REC的活动，以评估有效性并确定需要改进的领域。 通过实现这些目标，区域环境中心将实现其发展多样化科学家群体的目标， 更广泛地了解药物发现和开发的概念，挑战和机遇， 化学威胁剂的医学对策。