Connecting FEP Research and Practice through a Learning Health System

项目摘要 国家精神卫生研究所开发了早期精神病干预网络（EPINET）， 从国家实施的协调专科护理（CSC）首次发作精神病（FEP）。我们提出 EPINET节点[连接学习健康系统（LHS）]，将支持统一的数据收集，分析， 反馈和基础设施建设，以促进14个良好的持续质量改进文化- 在马里兰州和宾夕法尼亚州建立了CSC项目，每年在城市为500多名年轻的成年客户提供服务， 郊区和农村的环境。我们将实施一个核心评估组，并开发一个管理和 分析各项目的数据，并向项目提供有关患者结局和CSC忠诚度的反馈 模型根据我们在跨州临床医生培训和咨询方面的经验，我们将扩大现有的 学习协作CSC实施在马里兰州到一个跨州的LHS，将确定临床 问题，分析数据，并应用调查结果来优化我们所有CSC计划的实践。我们提出了一个 基于实践的研究项目，以适应非寻求治疗的重度 使用大麻的青少年以CSC参与为目标，药物依从性，降低风险以改善使用， 功能和恢复结果的FEP患者谁是持久的大麻用户。我们将与EPINET合作 国家数据协调中心实施标准措施，共享共同数据元素， 临床问题，以改善CSC的年轻人经历FEP。

Project Summary The National Institute of Mental Health has developed the Early Psychosis Intervention Network (EPINET) to learn from the national implementation of coordinated specialty care (CSC) for first episode psychosis (FEP). We propose an EPINET node [Connection Learning Health System (LHS)] that will support uniform data collection, analysis, feedback, and infrastructure development to promote a cultural of continuous quality improvement across 14 well- established CSC programs in Maryland and Pennsylvania serving over 500 young adult clients per year in urban, suburban, and rural settings. We will implement a core assessment battery and develop a system to manage and analyze data across programs and to provide feedback to programs on patient outcomes and fidelity to the CSC model. Building on our experience in cross-state clinician training and consultation, we will expand our existing learning collaborative for CSC implementation in Maryland into a cross-state an LHS that will identify clinical questions, analyze data, and apply findings to optimize practice across all of our CSC programs. We propose a practice-based research project to adapt a motivational interviewing intervention for nontreatment-seeking heavy cannabis-using adolescents to target CSC engagement, medication adherence, and risk reduction to improve use, functioning, and recovery outcomes in FEP patients who are persistent cannabis users. We will work with the EPINET National Data Coordinating Center to implement standard measures and share common data elements to answer clinical questions to improve CSC for young adults experiencing FEP.