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Gender Differences in Physical Activity Among Patients with Implantable Cardioverter Defibrillators (ICDs)

植入式心脏复律除颤器 (ICD) 患者体力活动的性别差异

基本信息

批准号：
10683989
负责人：
Lindsey Rosman
金额：
$ 17.18万
依托单位：
UNIV OF NORTH CAROLINA CHAPEL HILL
依托单位国家：
美国
项目类别：
财政年份：
2019
资助国家：
美国
起止时间：
2019-09-01 至 2024-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10683989
关键词：
Accelerometer Address Arrhythmia Behavioral Behavioral Medicine Biometry Cardiac Electrophysiologic Techniques Cardiac rehabilitation Cardiology Cardiovascular Diseases Cardiovascular system Characteristics Chronic Disease Clinic Clinical Clinical Management Clinical Trials Computerized Medical Record Data Data Analyses Databases Development Enrollment Environment Epidemiology Excess Mortality Feedback Future Gender Goals Health Healthcare Heart Heart Arrest Hour Implant Implantable Defibrillators Intervention K-Series Research Career Programs Knowledge Longitudinal trends Mental Depression Mentors Methods Monitor Morality Motivation Observational Study Online Systems Osteoporosis Outcome Outpatients Patient Outcomes Assessments Patient Recruitments Patients Pattern Physical activity Postdoctoral Fellow Psychologist Quality of life Recommendation Records Reporting Research Risk Risk Factors Sampling Self Efficacy Social support Surveys Technology Testing Time Training Woman Work adverse outcome behavior change cardiac device cardiac implant cardiovascular health career chronic pain cohort cost effective data integration disparity reduction evidence base exercise intervention expectation experience falls functional status gender difference health care disparity health disparity heart rhythm high risk population improved innovation insight knowledge base mHealth medical schools men mortality mortality risk multidisciplinary novel patient engagement patient oriented physical inactivity poor health outcome preference prospective recruit tool trend wireless transmission

项目摘要

PROJECT SUMMARY/ABSTRACT This career development award will facilitate Dr. Rosman’s transition to an independent research career and support her becoming a future leader in women’s cardiovascular health. It will equip her with the knowledge, tools, and experiences needed to develop patient-centered interventions to improve cardiovascular and quality of life outcomes in women with cardiac arrhythmias and implantable cardioverter-defibrillators (ICDs). These long-term goals are supported by a 5-year training plan to develop expertise in: (1) chronic disease epidemiology and biostatistics; (2) physical activity (PA) assessment and data analysis; (3) clinical trials; and (4) technology-based interventions (mHealth). She has assembled a multidisciplinary team of mentors who are experts in epidemiology, biostatistics, PA, cardiac electrophysiology, and technology-based (mHealth) clinical trials to facilitate her transition to independence in a rich research environment. Dr. Rosman is a Clinical Health Psychologist and a postdoctoral research fellow in Cardiovascular Behavioral Medicine at the Yale School of Medicine. This proposal builds logically on her clinical background and prior research, which has focused on functional status and quality of life outcomes in women with cardiovascular disease and patients with arrhythmias. For the past 6 years, much of Dr. Rosman’s clinical work and research has focused on a subset of arrhythmia patients with ICDs who have an elevated mortality risk due to physical inactivity. Women are among the least active ICD patients and have an elevated risk for adverse outcomes, yet participation in traditional PA interventions (e.g., cardiac rehabilitation) remains low. mHealth may offer an innovative and cost-effective method to engage women with ICDs, collect detailed behavioral data (e.g., from built-in ICD accelerometer), and integrate these data with patient-reported outcomes to provide targeted feedback in real-time and promote behavior change. Yet the knowledge base upon which to build these interventions for ICD patients and tailor it for women (e.g., gender differences in the patterns, predictors, and barriers to PA after ICD implant) is lacking. Also lacking is the requisite data concerning levels of PA associated with lower mortality risk, gender differences in these outcomes, and preferences for PA intervention(s). Dr. Rosman’s research plan will address these critical gaps in knowledge using longitudinal ICD-accelerometer and EMR data from a large, national sample of prospectively enrolled ICD patients. She will: AIM 1: examine gender differences in PA and risk factors for inactivity after ICD implant; and AIM 2: examine associations between PA and mortality in these patients. In AIM 3: she will conduct a survey of newly implanted ICD patients to identify gender differences in PA characteristics, goals, barriers, and preferences for PA intervention. The acceptability of mHealth technology will also be assessed. The proposed research will provide an evidence base to support my next career goal of developing and testing a patient-centered intervention to increase PA in women with ICDs.

项目总结/文摘

项目成果

期刊论文数量（12）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Insomnia and Early Incident Atrial Fibrillation: A 16-Year Cohort Study of Younger Men and Women Veterans.

DOI：
10.1161/jaha.123.030331
发表时间：
2023-10-17
期刊：
Journal of the American Heart Association
影响因子：
5.4
作者：
通讯作者：

Sex differences in device-measured physical activity after transcatheter aortic valve replacement.

经导管主动脉瓣置换术后设备测量的身体活动存在性别差异。

DOI：
发表时间：
2023
期刊：
The Journal of invasive cardiology
影响因子：
0
作者：
Mazzella,AnthonyJ;Gehi,AnilK;Searcy,Ryan;Vavalle,JohnP;Cavender,MatthewA;Rosman,Lindsey
通讯作者：
Rosman,Lindsey

Catheter Ablation and Cognitive Impairment in Atrial Fibrillation: Another Hit or a Silver Bullet?

心房颤动中的导管消融和认知障碍：另一个打击还是灵丹妙药？