Global TravEpiNet (GTEN): U.S. Travelers? Health Research, Surveillance, Communication and Outreach Network

项目摘要/摘要 国际旅行不仅可能增加个人旅行者感染的风险，而且可能 也助长了感染在全球的传播。更好地理解这一点 流行病学上重要的人群可导致改进干预措施(1)，以促进 国际旅行者的健康，以及(2)减少感染在国内的传播 社区。此应用程序侧重于为Global Travelers的 流行病学网络(Global TravEpiNet；GTEN)。GTEN的使命是减少 高危国际旅行者，包括VFR旅行者，并降低疾病的可能性 进口到美国。GTEN由三个组成部分组成：(1)美国国民 临床网站联盟，收集旅行前医疗保健的实时数据 美国(自成立以来，已收集了超过15万条记录)；(2)公众 健康外展计划(“健康回家”；www.headinghomeHealth.org)， 包括多种语言的网络工具和教育材料，适用于高风险和VFR 旅行者，以及为非专家提供者提供的临床指导工具，这些提供者提供了大部分 对这类旅行者的旅行前护理--这些努力包括与 公共卫生部门和纽约市和明尼阿波利斯/圣保罗的同事；以及 (3)旅行前和旅行后采集生物样本。我们建议在现有基础上扩展 由GTEN开发的基础设施，目的是(1)回答与 国际旅行的美国居民的医疗保健，(2)改善旅行前的医疗保健 提供给旅行相关疾病风险最高的美国弱势人群，以及(3) 定量评估与旅行有关的疾病和干预措施的影响。

PROJECT SUMMARY/ABSTRACT International travel may not only increase the risk of infection for an individual traveler, but may also contribute to the global spread of infections. A better understanding of this epidemiologically important population could lead to improved interventions (1) to promote the health of international travelers, and (2) to diminish the spread of infections within home communities. This application focuses on proposed efforts for the Global Travelers’ Epidemiology Network (Global TravEpiNet; GTEN). GTEN’s mission is to lessen illness among high-risk international travelers, including VFR travelers, and to reduce the likelihood of disease importation into the United States. GTEN is comprised of three components: (1) a U.S. national consortium of clinical sites that collects real-time data on pre-travel health care provided across the United States (since inception, over 150,000 records have been collected); (2) a public health outreach program (“Heading Home Healthy”; www.headinghomehealthy.org) that includes web-tools and educational materials in multiple languages for high risk and VFR travelers, as well as a clinical guidance tool for non-expert providers who deliver the majority of pre-travel care to such travelers -- these efforts involve established collaborations with Departments of Public Health and colleagues in New York City and Minneapolis/St. Paul; and (3) pre- and post-travel biosample collection. We propose to expand upon the existing infrastructure developed by GTEN in order to (1) answer fundamental questions relating to the health care of U.S. residents who travel internationally, (2) improve the pre-travel health care provided to vulnerable U.S. populations at highest risk of travel-related illness, and (3) quantitatively assess travel-related illnesses and the impact of interventions.