Project 3: Responding to Changing Serological and Viral Information around COVID-19 (RESPOND)

项目摘要 应对COVID-19大流行需要研究，以了解病毒如何传播， 如何获得和保持免疫力，以及如何最好地鼓励人们 利用现有的检测和疫苗。由于我们对血清学和病毒检测机会的了解， 测试结果的影响得到改善，我们为高风险个体提供指导的能力也得到提高。 暴露，如第一反应者及其家庭接触者，以及一般公众。通信 关于COVID-19相关风险的信息，可靠且针对适当受众量身定制， 个人做出最好的决定来保护自己。此外，当疫苗可用时， 彻底了解与疫苗接种有关的障碍和观念对于促进和 促进吸收。因此，将新的基础科学发现迅速翻译给适当的受众， 确保应对COVID-19传播的措施的有效性。 为此，项目3，“应对围绕COVID-19不断变化的血清学和病毒信息” （响应），”寻求利用项目1和2以及 与其他SeroNet中心和组件合作，开发可操作的沟通工具， 组织和个人，使他们能够利用最新的信息来指导他们的决定。 使用混合方法，包括第一年的定性访谈和调查，我们将首先制定一个 对利益攸关方组织使用的沟通机制的基本了解， 政府和行政卫生机构、医疗保健提供者组织和个人雇主 暴露和疾病传播的风险更高。我们还将评估对COVID-19的基线理解 高风险个人的风险和测试选项，包括第一反应者及其家庭接触者， 以及接受癌症治疗的患者。在第2-5年，我们将继续采用混合方法 通过后续访谈和调查，纳入项目1和2所了解的新信息， SeroNet合作者。在整个研究过程中，我们将通过一个项目网站传播我们的研究结果。 展示沟通最佳实践，并提供我们为特定利益相关者受众开发的工具， 以及公众。

Project Summary Responding to the COVID-19 pandemic requires research to understand how the virus is transmitted, what types of protection are most effective, how immunity is acquired and persists, and how to best encourage people to make use of available testing and vaccines. As our understanding of serologic and viral testing opportunities and implications of test results improves, so too does our ability to provide guidance to individuals at higher risk from exposure, such as first responders and their household contacts, as well as the general public. Communication about the risks related to COVID-19, which is reliable and tailored to the appropriate audience, empowers individuals to make the best decisions to protect themselves. Further, when a vaccine becomes available, a thorough understanding of the barriers and perceptions related to vaccination will be critical for promoting and facilitating uptake. Translating new basic science discoveries quickly and to the appropriate audiences will thus ensure the effectiveness of initiatives that can address the spread of COVID-19. To that end, Project 3, “Responding to Changing Serological and Viral Information around COVID-19 (RESPOND),” seeks to leverage information and discoveries from Projects 1 and 2, as well as from collaborations with other SeroNet Centers and Components, to develop actionable communication tools for organizations and individuals to empower them to utilize the most up-to-date information to guide their decisions. Using a mixed methods approach, including qualitative interviews and surveys in Year 1, we will first develop a baseline understanding of the communication mechanisms used by stakeholder organizations such as government and administrative health agencies, healthcare provider organizations, and employers of individuals at higher risk of exposure and disease transmission. We will also assess baseline understanding of COVID-19 risks and testing options by individuals at higher risk, including first responders and their household contacts, as well as patients undergoing cancer treatment. In Years 2-5, we will continue our mixed methods approach through follow-up interviews and surveys incorporating new information learned Projects 1 and 2, and from SeroNet collaborators. Throughout the study we will disseminate our findings through a project website presenting communication best practices and providing tools we develop for specific stakeholder audiences, as well as the general public.