Project 3: Responding to Changing Serological and Viral Information around COVID-19 (RESPOND)

项目摘要 应对新冠肺炎大流行需要进行研究，以了解病毒是如何传播的，是什么类型 最有效的保护，免疫力是如何获得和持续的，以及如何最好地鼓励人们 利用可用的检测和疫苗。随着我们对血清学和病毒检测机会的理解以及 检测结果的影响得到了改善，我们为患癌症风险较高的人提供指导的能力也得到了提高 接触者，如急救人员及其家庭接触者，以及普通公众。沟通 关于与新冠肺炎相关的风险，这是可靠的，并为适当的受众量身定做，增强了 让个人做出最好的决定来保护自己。此外，当有疫苗可用时， 彻底了解与疫苗接种有关的障碍和看法将是促进和 促进理解。因此，快速地将新的基础科学发现转化为适当的受众将 确保能够应对新冠肺炎传播的倡议的有效性。 为此，项目3《应对新冠肺炎周围不断变化的血清学和病毒信息》 (答复)，“寻求利用项目1和2以及项目2的信息和发现。 与其他SeroNet中心和组件协作，以开发可操作的通信工具 使组织和个人能够利用最新信息来指导他们的决策。 采用混合方法，包括第一年的定性访谈和调查，我们将首先制定一个 对利益相关者组织使用的沟通机制的基线理解，例如 政府和行政卫生机构、医疗保健提供者组织和个人雇主 有更高的暴露和疾病传播风险。我们还将评估对新冠肺炎的基线理解 风险和风险较高的个人的检测选择，包括第一反应人员及其家庭接触者，如 以及接受癌症治疗的患者。在第二年到第五年，我们将继续采用混合方法 通过后续访谈和调查纳入新学到的信息项目1和2，并从 SeroNet的合作者。在整个研究过程中，我们将通过一个项目网站发布我们的研究结果 介绍沟通最佳实践，并提供我们为特定利益相关者受众开发的工具，如 和普通民众一样。

Project Summary Responding to the COVID-19 pandemic requires research to understand how the virus is transmitted, what types of protection are most effective, how immunity is acquired and persists, and how to best encourage people to make use of available testing and vaccines. As our understanding of serologic and viral testing opportunities and implications of test results improves, so too does our ability to provide guidance to individuals at higher risk from exposure, such as first responders and their household contacts, as well as the general public. Communication about the risks related to COVID-19, which is reliable and tailored to the appropriate audience, empowers individuals to make the best decisions to protect themselves. Further, when a vaccine becomes available, a thorough understanding of the barriers and perceptions related to vaccination will be critical for promoting and facilitating uptake. Translating new basic science discoveries quickly and to the appropriate audiences will thus ensure the effectiveness of initiatives that can address the spread of COVID-19. To that end, Project 3, “Responding to Changing Serological and Viral Information around COVID-19 (RESPOND),” seeks to leverage information and discoveries from Projects 1 and 2, as well as from collaborations with other SeroNet Centers and Components, to develop actionable communication tools for organizations and individuals to empower them to utilize the most up-to-date information to guide their decisions. Using a mixed methods approach, including qualitative interviews and surveys in Year 1, we will first develop a baseline understanding of the communication mechanisms used by stakeholder organizations such as government and administrative health agencies, healthcare provider organizations, and employers of individuals at higher risk of exposure and disease transmission. We will also assess baseline understanding of COVID-19 risks and testing options by individuals at higher risk, including first responders and their household contacts, as well as patients undergoing cancer treatment. In Years 2-5, we will continue our mixed methods approach through follow-up interviews and surveys incorporating new information learned Projects 1 and 2, and from SeroNet collaborators. Throughout the study we will disseminate our findings through a project website presenting communication best practices and providing tools we develop for specific stakeholder audiences, as well as the general public.