Community-Engaged Structural Approaches to Prevent Violence and Improve HIV Prevention and Care Outcomes Among Trans Women of Color

社区参与的结构性方法，以防止有色人种跨性别女性的暴力并改善艾滋病毒预防和护理结果

• 批准号: 10693570
• 负责人: Sarah Peitzmeier
• 金额: $ 17.91万
• 依托单位: UNIVERSITY OF MICHIGAN AT ANN ARBOR
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-04-01 至 2027-03-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10693570
• 关键词: AIDS prevention; Academy; Address; Affect; Applications Grants; Automobile Driving; Behavior; Behavior Therapy; Biosocial; Black race; Caring; Collaborations; Communities; Data; Diagnosis; Economics; Epidemic; Equity; Ethnography; Evaluation; Explosion; Focus Groups; Funding; Future; HIV; HIV disparities; Health; Homelessness; Housing; Hybrids; Imprisonment; Individual; Inequity; Intervention; Intervention Studies; Intervention Trial; Interview; Investments; Israel; Knowledge; Latina; Learning; Maps; Mental Health; Mental health promotion; Mentors; Mentorship; Michigan; National Institute of Mental Health; Nature; Needs Assessment; Observational Study; Personal Satisfaction; Population; Poverty; Process; Protocols documentation; Public Health Schools; Reporting; Research; Research Personnel; Resource Sharing; Resources; Risk; School Nursing; Science; Scientist; Sexism; Structure; Time; Training; Training Activity; Training Support; United States National Institutes of Health; Universities; Violence; Woman; Work; Writing; behavior change; care outcomes; career; community based participatory research; community partnership; design; efficacy/implementation trial; empowerment; experience; food insecurity; gender affirmation; gender-based violence; implementation science; improved; informant; innovation; intimate partner violence; pilot trial; prevent; professor; programs; racial disparity; racism; scale up; service providers; sex; skills; social stigma; structural determinants; structural health determinants; syndemic; theories; therapy design; transgender; transgender women; trauma symptom; trial design; violence prevention; women of color

PROJECT ABSTRACT This K01 application to NIMH will enable a concentrated four-year intensive training and mentored research program designed to transition Dr. Sarah Peitzmeier from her current observational research focus to a new research agenda designing and evaluating structural interventions within a community-based participatory research (CBPR) context for integrated HIV and violence prevention and mental health promotion, in partnership with trans women of color. Dr. Peitzmeier is an assistant professor at the University of Michigan School of Nursing and School of Public Health, which houses one of the oldest CBPR partnerships and academies nationally (the Detroit Urban Research Center) and is a powerhouse of HIV intervention research. Racism, sexism, HIV stigma, cisgenderism, and other interlocking forms of oppression generate mutually reinforcing structural vulnerabilities for trans women of color, including gender-based violence (GBV), poverty, homelessness, and sex work. These structural vulnerabilities synergistically interact to elevate risk of HIV. However, interventions to address these deeply entrenched upstream structural determinants of HIV in this population are limited, which in turn limits the efficacy of downstream individual behavioral interventions while these determinants remain intact. The proposed work will 1) Identify community priorities for a structural intervention for integrated HIV/GBV prevention through forming a CBPR partnership with trans women of color and service providers in Detroit and conducting an Action-Oriented Community Diagnosis, 2) Develop a grounded theory of how trans women's participation in a cash-plus cash transfer intervention affects their experience of GBV, HIV-related behaviors, and mental health, and 3) Collaboratively design a status-neutral intervention to promote HIV prevention and care, reduce mental health burden, and prevent GBV against trans women of color. The research will be underpinned by coursework in CBPR, structural interventions, intervention trial design, and implementation science, as well as invaluable mentored learning experiences observing the implementation and evaluation of diverse structural interventions (Drs. Darbes, Sherman, Gamarel, and Pettifor) and CBPR partnerships (Gamarel, Israel, Brush, Rivera) from renowned experts in the field. Overall, the research will generate rich preliminary data, a finalized intervention protocol, a concrete strategy for funding and implementing the intervention, a pilot hybrid efficacy-implementation trial design for evaluating the intervention, and a strong CBPR partnership as a fruitful platform for Dr. Peitzmeier's ongoing research agenda in partnership with this community. By supporting didactic and field-based learning and protected time for research and CBPR partnership building, a K01 will advance Dr. Peitzmeier's career progression as an independent, community-based HIV intervention scientist focused on structural determinants of health, leading to better health and wellbeing among trans women of color, an NIH priority population.

项目摘要 对NIMH的K01申请将进行集中的四年密集培训并进行指导 研究计划旨在将莎拉·佩茨迈耶（Sarah Peitzmeier）博士从目前的观察研究重点转移到 一项新的研究议程，设计和评估基于社区的结构干预措施 参与性研究（CBPR）综合艾滋病毒和暴力预防和心理健康促进的情况， 与有色人种的跨性别女性合作。 Peitzmeier博士是密歇根大学的助理教授 护理学院和公共卫生学院，它是CBPR合作伙伴最古老的合作伙伴之一 全国学院（底特律城市研究中心），是艾滋病毒干预研究的强国。 种族主义，性别歧视，艾滋病毒污名，西斯加德主义和其他互锁的压迫形式会产生 相互加强有色人种的跨性别女性的结构脆弱性，包括基于性别的暴力（GBV）， 贫穷，无家可归和性工作。这些结构性脆弱性协同相互作用，以提高 艾滋病病毒。但是，解决这些深深根深蒂固的艾滋病毒上游结构决定因素的干预措施 该人群有限，这反过来限制了下游个体行为干预的功效 尽管这些决定因素仍然完好无损。拟议的工作将1）确定结构性的社区优先事项 通过与有色人种的跨性别女性建立CBPR合作伙伴关系，用于预防综合艾滋病毒/GBV综合的干预 和底特律的服务提供商并进行了以行动为导向的社区诊断，2）开发 关于跨性别妇女参与现金加现金转移干预如何影响其的基础理论 GBV，与HIV相关的行为和心理健康的经验，以及3）协作设计一种状态中性 干预以促进艾滋病毒预防和护理，减轻心理健康负担，并防止GBV反对跨性别 有色女人。 该研究将以CBPR，结构干预，干预试验的课程为基础 设计和实施科学以及无价的指导学习经验观察 实施和评估各种结构干预措施（Darbes博士，Sherman，Gamarel和 Pettifor）和CBPR合作伙伴关系（以色列，刷子，Rivera）来自该领域的专家。全面的， 该研究将产生丰富的初步数据，最终的干预协议，这是一种具体策略 资金和实施干预措施，试点混合功效 - 实施试验设计，用于评估 干预，以及强大的CBPR合作伙伴关系，是Peitzmeier博士正在进行的研究议程的富有成果的平台 与这个社区合作。通过支持教学和基于现场的学习并保护时间 研究与CBPR合作伙伴建设，K01将推动Peitzmeier博士的职业发展作为 独立的，基于社区的艾滋病毒干预科学家专注于健康的结构决定因素，领先 为了改善有色人种的跨性别女性，NIH优先人口。