NYUCI-ES: Psychosocial Intervention to Improve Health Outcomes for Chinese and Korean ADRD Caregivers

NYUCI-ES：通过心理社会干预改善中国和韩国 ADRD 护理人员的健康状况

• 批准号: 10693231
• 负责人: Bei Wu
• 金额: $ 68.12万
• 依托单位: RUTGERS BIOMEDICAL AND HEALTH SCIENCES
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-24 至 2026-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10693231
• 关键词: 2 arm randomized control trial; Adult; Alzheimer' s disease related dementia; American; Area; Asian; Asian Americans; Asian population; Belief; Biological; Biological Assay; Blood specimen; COVID-19; Cardiometabolic Disease; Caregivers; Caring; Chinese; Chinese American; Chronic Disease; Collaborations; Conflict (Psychology); Control Groups; Counseling; Cultural Backgrounds; Dementia; Dementia caregivers; Diabetes Mellitus; Disease Management; Educational Materials; Elderly; Emotional; Enrollment; Ethnic Origin; Evidence based intervention; Failure; Family; Family Caregiver; Glycosylated Hemoglobin; Health; Health Policy; Health Promotion; Hypertension; Individual; Inflammation; Intake; Intervention; Korean American; Koreans; Language; Linguistics; Mainstreaming; Mediating; Mediator; Mental Depression; Mental Health; Mental Health Services; Metabolic; Metabolism; Minority; Minority Groups; Modeling; Morbidity - disease rate; Multilingualism; New Jersey; New York; Nursing Homes; Outcome; Oxidative Stress; Patient Self-Report; Personal Satisfaction; Persons; Physiological; Policies; Population; Psychosocial Factor; Public Health; Quality of life; Questionnaires; Randomized; Research; Research Project Grants; Risk; Risk Factors; Sampling; Self Management; Services; Social Work; Social isolation; Social support; Stereotyping; Stress; Structure; Support Groups; Testing; Translating; biological adaptation to stress; cardiometabolic risk; caregiver interventions; caregiving; caregiving outcomes; community organizations; comparison control; cultural values; dementia care; dementia caregiving; depressive symptoms; efficacy testing; evidence base; follow-up; group intervention; health equity; health literacy; improved; lipid metabolism; metropolitan; multi-component intervention; peer support; physical conditioning; provider intervention; psychological outcomes; psychosocial; service providers; social; social media; social stigma; underserved community

Research Project 3 – NYUCI-ES – Abstract The physical and emotional demands of dementia caregiving can have enormous negative effects on caregivers’ physical and mental health. Dementia caregivers have increased risk of hypertension and diabetes, compared to non-caregivers, especially in minority populations. This study will conduct a two-arm randomized controlled trial to test the efficacy of a culturally tailored version of the NYU Caregiver Intervention (NYUCI) plus enhanced support (ES) through online chat groups (the NYUCI plus WeChat/Kakaotalk [population social media app for Chinese/Korean] peer support which we call the NYUCI-ES in reducing health risks for cardiometabolic disease among older Chinese and Korean-American adults caring for relatives with ADRD. The NYUCI has proven efficacy in reducing psychological outcomes among largely White samples of caregivers of persons with ADRD and has been widely replicated and translated in the USA and elsewhere. This study will provide the first large- scale test of the potential effects of the NYUCI-ES, a multicomponent intervention that includes individual and family counseling and ongoing support via support group and online chat groups and ad hoc (on demand) counseling. In collaboration with community organizations across the New York and northern New Jersey metropolitan area, we will enroll 300 caregivers of people with ADRD (150 Chinese and 150 Korean) in this study. Aim 1: Develop culturally adapted informational and educational materials about dementia and caregiving issues for social service providers of the intervention and for family caregivers. Aim 2: Test the hypothesis, H1: A counseling and support intervention (the NYUCI-ES) will significantly improve psychosocial factors such as depression, stress self-rated health and chronic disease management among Chinese and Korean-American ADRD caregivers and these changes will be mediated by improvement in social support. H1a: By the first (6- month) follow-up, the mediators (increases in social support, stress reaction) will improve significantly in the intervention group compared to baseline values and the control group. H1b: These improvements will be maintained, and lead to reduction in depressive symptoms, and improvement in self-reported health and chronic disease self-management by the 12-month follow-up compared to the control group. Aim 3: Test the hypothesis, H2: the NYUCI-ES will reduce biologic risk factors, including metabolic health (glycosylated hemoglobin) and inflammation (Oxidative stress, lipid metabolism, etc.) within 6 months of enrollment compared to baseline and a control group; these changes will be mediated through increases in social support and decreases in depressive symptoms and will be maintained at the 12-month follow-up. The public health significance of these findings will likely have an impact on health care policy for CGs from diverse underserved ethnic and cultural backgrounds, potentially reducing morbidity, and improving their quality of life.

研究项目3 - NYUCI-ES -摘要 痴呆症患者的身体和情感需求会对照顾者的健康产生巨大的负面影响。 身心健康。痴呆症照顾者患高血压和糖尿病的风险增加， 尤其是在少数群体中。本研究将进行一项两组随机对照研究， 一项测试纽约大学护理人员干预（NYUCI）文化定制版本的有效性的试验， 通过在线聊天组（NYUCI加上微信/Kakaotalk [人口社交媒体应用程序， 中国/韩国]同行支持，我们称之为NYUCI-ES，以降低心脏代谢疾病的健康风险 在照顾ADRD亲属的中国和韩裔美国老年人中。纽约大学CI已经证明 在ADRD患者的照顾者的大部分白色样本中减少心理结局的有效性 并在美国和其他地方被广泛复制和翻译。这项研究将提供第一个大的- NYUCI-ES的潜在影响的规模测试，一个多成分干预，包括个人和 通过支持小组和在线聊天小组以及临时（按需）提供家庭咨询和持续支持 辅导 与纽约和北方新泽西的社区组织合作 大都会地区，我们将招募300名ADRD患者的护理人员（150名中国人和150名韩国人）， study.目标1：编制适应文化的关于痴呆症和痴呆症的信息和教育材料 干预措施的社会服务提供者和家庭照顾者的问题。目标2：检验假设，H1： 咨询和支持干预（NYUCI-ES）将显着改善心理社会因素，如 中国人和韩裔美国人抑郁、压力自测健康与慢性病管理 ADRD照顾者和这些变化将介导的社会支持的改善。H1 a：由第一个（6- 月）随访时，介导因子（社会支持增加、应激反应）会明显改善， 干预组与对照组基线值比较。H1B：这些改进将是 保持，并导致抑郁症状的减少，以及自我报告的健康和慢性疾病的改善。 通过12个月的随访与对照组进行疾病自我管理比较。目标3：检验假设， H2：NYUCI-ES将减少生物风险因素，包括代谢健康（糖化血红蛋白）和 炎症（氧化应激、脂质代谢等）与基线相比，入组后6个月内， 控制组;这些变化将通过增加社会支持和减少抑郁来介导。 症状，并将在12个月随访时维持。 这些发现的公共卫生意义可能会对CG的医疗保健政策产生影响 从不同的服务不足的种族和文化背景，潜在地降低发病率，并提高他们的 生活质量