Administrative and Statistics Core

行政和统计核心

• 批准号: 10693141
• 负责人: ANTONI RIBAS
• 金额: $ 31.09万
• 依托单位: UNIVERSITY OF CALIFORNIA LOS ANGELES
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-11 至 2025-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10693141
• 关键词: Administrative Coordination; Bioinformatics; Biometry; Biostatistics Core; Budgets; Clinical Research; Clinical Trials; Combined Modality Therapy; Communication; Comprehensive Cancer Center; Computer software; Consultations; Contracts; Data; Development; Ensure; Evaluation; Experimental Designs; Fostering; Goals; Government; Grant; Infrastructure; Knowledge; Laboratory Study; Leadership; Manuscripts; Mediating; Methodology; Minority; Monitor; Mus; Occupational activity of managing finances; Policies; Preparation; Program Efficiency; Progress Reports; Protocols documentation; Publications; Quality Control; Records; Regulation; Reporting; Research; Research Personnel; Research Project Grants; Research Support; Resistance; Resource Sharing; Role; Sample Size; Sampling; Schedule; Science; Scientific Advances and Accomplishments; Services; Statistical Data Interpretation; Supervision; Technology; Training; United States National Institutes of Health; Universities; Woman; conflict resolution; daily functioning; data management; design; meetings; melanoma; mouse model; programs; prospective; recruit; statistics

ADMINISTRATIVE AND STATISTICS CORE A ABSTRACT The Administrative and Statistics Core (Admin and Stats Core) provides leadership, oversight and administrative support for the research programs, as well as biostatistical support and oversight. In particular, it provides administrative and fiscal management, clerical support, manuscript submission, meeting organization, data management, quality control, and planning and evaluation of the grant, leaving the research investigators free to concentrate on science. It has two specific aims, one focused on scientific and operational oversight, which includes an Internal Advisory Board (IAB) and help from ad hoc External Expert Consultants (EEC). The second aim provides administrative and fiscal oversight to the overall grant. Within this aim is included the communication and consultation with the NCI program officer and other staff, progress reports and tracking shared resource use. The key importance to the Core's services is the Core's biostatistical support, which includes: 1) biostatistical design of laboratory and clinical studies, including prospective design of the sample size calculations for murine studies proposed in all three Projects and design of sample clinical trial and sample analyses in the clinical studies proposed in Projects 1 and 3; 2) statistical monitoring of studies to ensure interpretability of results; 3) supervision and analytical assistance to multiple investigators regarding study protocol data entry/statistical analyses and analysis software; 4) development of biostatistical methodology for statistical problems in these projects; and 5) assistance with manuscript preparation.

行政和统计核心A摘要 行政和统计核心(行政和统计核心)提供领导、监督和 对研究项目的行政支持，以及生物统计学支持和监督。特别是，它 提供行政和财务管理、文书支持、稿件提交、会议组织、 数据管理、质量控制以及赠款的规划和评估，将研究人员 可以自由地专注于科学。它有两个具体目标，一个侧重于科学和业务监督， 其中包括内部咨询委员会(IAB)和临时外部专家顾问(EEC)的帮助。这个 第二个目标是对整个赠款进行行政和财政监督。在这一目标中包括 与NCI项目官员和其他工作人员进行沟通和协商、进度报告和跟踪 共享资源使用。核心服务的关键重要性是核心的生物统计支持，这 包括：1)实验室和临床研究的生物统计设计，包括样本的前瞻性设计 所有三个项目中提出的小鼠研究的规模计算和样本临床试验的设计 项目1和3中提议的临床研究的样本分析；2)对研究进行统计监测，以 确保结果的可解释性；3)监督和分析协助多名调查人员 研究方案数据录入/统计分析和分析软件；4)开发生物统计学 这些项目中统计问题的方法；以及5)协助手稿准备。