UT Southwestern Medical Center Simmons Comprehensive Cancer Center

UT 西南医学中心西蒙斯综合癌症中心

• 批准号: 10693201
• 负责人: Carlos L Arteaga
• 金额: $ 430.61万
• 依托单位: UT SOUTHWESTERN MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-09-01 至 2026-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10693201
• 关键词: Address; Authorization documentation; Award; Basic Science; Biometry; Cancer Biology; Cancer Burden; Cancer Center; Cancer Center Support Grant; Cancer Control; Cancer Science; Caring; Catchment Area; Chemistry; Child; Clinic; Clinical; Clinical Investigator; Clinical Sciences; Clinical Trials; Collaborations; Communities; Community Health Education; Community Outreach; Comprehensive Cancer Center; County; Coupling; Data Science; Development; Diagnosis; Disparity; Education; Educational Activities; Ensure; Extramural Activities; Fostering; Funding; Generations; Growth; Health; Health Personnel; Health system; Hospitals; Improve Access; Infrastructure; Institution; Intervention; Investigational Therapies; Investments; Laboratories; Leadership; Malignant Neoplasms; Medical center; Mission; Movement; National Cancer Institute; Outcome; Outpatients; Patient Care; Patients; Physicians; Pilot Projects; Population Heterogeneity; Population Sciences; Population Study; Positioning Attribute; Prevention; Prevention approach; Prevention education; Qualifying; Renal carcinoma; Research; Research Personnel; Research Project Grants; Resource Sharing; Resources; Scientist; Secure; Shoulder; Strategic Planning; System; Texas; Tissues; Training and Education; Translating; Translational Research; Vision; animal imaging; anticancer research; authority; cancer care; cancer education; cancer health disparity; cancer prevention; cancer therapy; clinical care; clinical investigation; community engagement; design; empowerment; high throughput screening; improved; innovation; international center; live cell imaging; member; multidisciplinary; next generation; novel strategies; operation; outreach; outreach program; programs; rapid growth; recruit; training opportunity; translational impact

The Harold C. Simmons Comprehensive Cancer Center (SCCC) is the National Cancer Institute (NCI)- designated cancer center of the UT Southwestern Medical Center (UTSW) and its health system affiliates, Parkland Health & Hospital System, and Children’s Medical Center of Dallas. SCCC’s mission is to ease the burden of cancer through ground-breaking discovery, transdisciplinary research, impactful community engagement, education, and exceptional patient care. Upon arrival as the new Director in 2017, Carlos L. Arteaga, MD, shouldered authority over UTSW cancer activities and recasted a vision for the Center that focuses on the translation of science into the forefront of UTSW’s overall mission. To accomplish this, the SCCC Strategic Plan 2020-2025 prioritizes an increase in cancer-focused funding and infrastructure support for clinical trials, expansion of the clinical capacity for cancer treatment through further developed multidisciplinary cancer care, a new > 300,000 sf. Outpatient Cancer Care Tower, and a renewed emphasis on community outreach and engagement. In addition, SCCC will continue to create educational and training opportunities aimed at empowering a new generation of basic scientists, physician-scientists, clinical investigators, and other healthcare providers to make a difference in cancer discovery, clinical investigation and care, cancer control, and community outreach. The Center’s operations are optimized through a visionary and highly qualified Senior Leadership team and a value-creating administrative infrastructure. Together, leadership, infrastructure, and an engaged Center membership of 227 scientists and clinical investigators are organized into five highly interactive research programs—Cellular Networks in Cancer, Development and Cancer, Chemistry and Cancer, Experimental Therapeutics, and Population Science and Cancer Control. During the current six-year funding cycle, SCCC has secured several large collaborative multi-investigator awards, including a new SPORE in kidney cancer, six new U01s, and two new U54s, and maintains two NCI-funded T32s. As a result of strengthening the clinical trials infrastructure, accruals to interventional clinical trials has more than doubled. The rapid pace of discovery and movement toward effective translational research is supported by six shared resources: Biostatistics, Data Science, High Throughput Screening, Live Cell Imaging, Small Animal Imaging, and Tissue Management. Today, SCCC has $25M in annual direct NCI funding. It has successfully leveraged Cancer Center Support Grant (CCSG) funding during the current period to continue the rapid growth of the Center, as demonstrated by the recruitment of 97 new members. SCCC has invested $210M since 2014 (six years) and has secured another $232M in institutional commitment for the next five years to increase the range of available resources. These impressive developments ensure that catchment area needs and concerns are addressed and SCCC scientists will continue their exemplary track record in advancing understanding of cancer biology while coupling these findings with the development of novel approaches to cancer control, diagnosis, and treatment.

哈罗德·西蒙斯综合癌症中心(SCCC)是美国国家癌症研究所(NCI)- 德克萨斯大学西南医学中心(UTSW)及其卫生系统附属机构指定的癌症中心， 帕克兰健康与医院系统和达拉斯儿童医疗中心。SCCC的使命是缓解 通过突破性的发现、跨学科的研究、有影响力的社区来减轻癌症的负担 参与、教育和特殊的病人护理。2017年，卡洛斯·L·卡洛斯就任新任董事。 阿特亚加，医学博士，肩负着UTSW癌症活动的权威，并重塑了该中心的愿景，专注于 关于将科学转化为UTSW总体使命的前沿。为了实现这一目标，SCCC战略 2020-2025年计划优先增加以癌症为重点的资金和临床试验的基础设施支持， 通过进一步发展多学科癌症护理来扩大癌症治疗的临床能力， 新的&gt；30万平方英尺。门诊癌症护理塔，并重新重视社区外展和 订婚。此外，SCCC将继续创造教育和培训机会，旨在 支持新一代基础科学家、内科科学家、临床研究人员和其他医疗保健人员 提供者在癌症发现、临床研究和护理、癌症控制和社区方面发挥作用 外展。通过一个有远见和高素质的高级领导团队，中心的运作得到了优化 以及创造价值的行政基础设施。领导力、基础设施和参与式中心 227名科学家和临床研究人员的成员被组织成五项高度互动的研究 癌症细胞网络，发育与癌症，化学与癌症，实验 治疗学、人口科学和癌症控制。在当前的六年筹资周期中，SCCC有 获得了几个大型协作多研究员奖，包括肾癌的一个新孢子，六个新的 U01和两架新的U54，并维护两架NCI资助的T32。由于加强了临床试验 在基础设施方面，干预性临床试验的收益增加了一倍多。发现和发现的快速步伐 走向有效的翻译研究的运动得到了六个共享资源的支持：生物统计、数据 科学、高通量筛选、活细胞成像、小动物成像和组织管理。今天, SCCC每年有2500万美元的NCI直接资金。它成功地利用了癌症中心支持赠款 (CCSG)在本期间提供资金，以继续中心的快速增长，如以下所示 招募97名新成员。自2014年(6年)以来，SCCC已投资2.1亿美元，并获得了另一笔 未来五年2.32亿美元的机构承诺，以扩大可用资源的范围。这些 令人印象深刻的发展确保了集水区的需求和关切得到解决，SCCC的科学家 将继续他们在促进对癌症生物学的理解方面的模范记录，同时将这些 随着癌症控制、诊断和治疗的新方法的发展，这些发现。