Cancer Center Support Grant - UT Southwestern Medical Center

 描述（由申请人提供）：得克萨斯大学西南西蒙斯癌症中心正在提交癌症中心支持补助金的竞争性续期申请，6-10年。西蒙斯癌症中心是一个矩阵中心，整合了癌症研究，临床癌症护理和癌症控制外展在得克萨斯大学西南（UTSW）医学中心及其附属医院系统，UTSW卫生系统，帕克兰健康和医院系统，儿童医疗中心达拉斯，和UTSW蒙克里夫癌症研究所在沃斯堡。与德克萨斯大学公共卫生学院达拉斯地区校区的研究联系，位于UTSW校园的MPH和博士学位授予计划，将公共卫生专业知识和培训机会带入中心。西蒙斯癌症中心压倒一切的使命是利用这些附属机构创造新的知识，以改善达拉斯，北德克萨斯州和全国的癌症结果。西蒙斯癌症中心的164名成员被组织成五个科学项目-发展与癌症，癌细胞网络，化学与癌症，癌症实验治疗，人口科学与癌症控制。这些项目具有高度互动性，在过去的资助期内，获得了22项多研究者赠款，合作出版比例为52%。申请中要求提供资金用于高级领导人和项目领导人、规划和评估、发展基金、行政、早期临床研究支持、方案审查和监测系统、临床方案和数据管理以及六项共享资源，其中两项用于研究设计和数据分析分组（生物统计学、生物信息学）;和翻译分组中的四个（高通量筛选、小动物成像、活细胞成像和组织管理）。CCSG对这些组成部分的支持得到了机构资金的补充，以确保中心拥有实现其使命所需的基础设施。此外，西蒙斯癌症中心还创造了动态的教育和培训机会，旨在使新一代科学家，医生和其他医疗保健提供者能够在癌症发现，临床护理和控制方面发挥作用。 西蒙斯癌症中心整合了癌症研究，临床癌症护理和癌症控制外展整个得克萨斯大学西南医学中心及其附属医院系统。该中心压倒一切的使命是利用这些附属机构和特殊的资源来改善达拉斯-沃斯堡（DFW）地区和全国的癌症预后。

 DESCRIPTION (provided by applicant): The University of Texas Southwestern Simmons Cancer Center is submitting this competitive renewal application for a Cancer Center Support Grant, Years 6-10. The Simmons Cancer Center is organized as a matrix center that integrates cancer research, clinical cancer care, and cancer control outreach across the University of Texas Southwestern (UTSW) Medical Center and its affiliated hospital systems, UTSW Health System, Parkland Health and Hospital System, Children's Medical Center of Dallas, and UTSW Moncrief Cancer Institute in Fort Worth. A research affiliation with the Dallas Regional Campus of the University of Texas School of Public Health, an MPH and PhD granting program located on the UTSW campus, brings public health expertise and training opportunities into the center. The overriding mission of the Simmons Cancer Center is to leverage these affiliations to create new knowledge to improve cancer outcomes in Dallas, North Texas, and the nation. The 164 members of the Simmons Cancer Center are organized into five scientific programs- Development and Cancer, Cancer Cell Networks, Chemistry and Cancer, Experimental Therapeutics of Cancer, and Population Science and Cancer Control. These programs are highly interactive, with 22 multi-investigator grants awarded and a 52% collaborative publication ratio over the past grant period. Funds are requested in the application for Senior Leaders and Program Leaders, Planning and Evaluation, Developmental Funds, Administration, Early Phase Clinical Research Support, Protocol Review and Monitoring System, Clinical Protocol and Data Management, and six shared resources including two in a research design and data analytics grouping (biostatistics, bioinformatics); and four in a translational grouping (high throughput screening, small animal imaging, live cell imaging, and tissue management). CCSG support for these components is supplemented by institutional funds to ensure that the center has the infrastructure required to achieve its mission. In addition, the Simmons Cancer Center has created dynamic educational and training opportunities designed to equip a new generation of scientists, physicians, and other health care providers to make a difference in cancer discovery, clinical care, and control. The Simmons Cancer Center integrates cancer research, clinical cancer care, and cancer control outreach across the University of Texas Southwestern Medical Center and its affiliated hospital systems. The overriding mission of the center is to leverage these affiliations and the exceptional resources available to improve cancer outcomes in the Dallas-Fort Worth (DFW) region and the nation.