Duke Preparing Research Scholars in Biomedical Sciences- Post-Baccalaureate Research Education Program

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Abstract The U.S. continues to face barriers to advancing biomedical innovation. Ongoing challenges include an insufficient number of individuals from underrepresented backgrounds entering biomedical training and high attrition from the research training path. To address these barriers, we are developing a multi-track post- baccalaureate research scholars program: the Duke Preparing Research scholars In bioMEdical sciences-Post- baccalaureate Research Education Program (PRIME-PREP), which leverages Duke University's training expertise, a strong multiple-PI leadership team composed of individuals with overlapping expertise in research and mentoring, an internal and external advisory board with demonstrated commitment to training, equity and inclusion and a cohort of diverse, experienced and passionate mentors with demonstrated commitment to training and diversity. To ensure inclusive and productive mentoring relationships, research mentors have been identified based on their mentorship records and their established, funded independent research programs. Prospective mentors will complete mentor training before placement of scholars in their laboratories, promoting a culture of effective and supportive mentoring necessary for the success of the next generation of biomedical scientists from diverse backgrounds. Drawing on the Diversity in STEM Coalition (DISC) – a coalition of regional undergraduate and minority-serving institutions – to identify and recruit strong candidates from underrepresented backgrounds, PRIME-PREP will seek to enhance students’ success in entering and completing research- focused doctoral degree programs. PRIME-PREP Scholars will participate in a tailored professional development curriculum that prepares them for successful entry into PhD and MD-PhD programs. In addition to peer networking within the PRIME-PREP cohort, scholars will have access to a community of peers, near-peers, and leaders across Duke University. The one-year PRIME-PREP will place students in laboratories, where a mentored research experience will comprise 75% of their time. Professional development activities and workshops will comprise 25% of their time, including a 6-week summer bridge program at the beginning of the year, training in community engaged research and professional development workshops. By implementing and adapting evidence-based PREP frameworks, PRIME-PREP will place at least 75% of participants in PhD or MD- PhD programs within two years of program completion.