Administrative Core

管理核心(核心A)摘要 由Jeffrey Myers博士和Vlad Sandulache博士领导并得到该中心支持的行政核心 管理员托因·巴巴林德博士是休斯顿获得性抵抗中心不可或缺的组成部分 研究(H-CARR)。行政核心(核心A)的总体目标是提供关键的集中化 支持H-CARR，确保三个项目和核心之间的无缝互动和整合 在中心内以及更广泛的Artnet社区内。核心A旨在监控研究活动和 提供稳定和持续的领导，指导本研究中心未来的科学方向。堆芯 A将利用中心咨询小组在关键领域的广泛科学和研究相关经验 决策步骤。行政核心将确保强调基本机制和翻译 研究和促进跨学科和项目间整合，包括协助建立 与其他Artnet中心以及U24 Artnet协调数据和管理中心的协作 (Artnet CDMC U24)和NCI工作人员。核心A还将全面负责财政和预算 管理H-CARR，包括雇用关键人员，以确保高素质、良好的 经过培训、管理和多样化的员工队伍，以经济高效的方式使用资源。这 CORE还将监控所有机构、州、联邦和NCI的科学完整性和总体合规性 法规和要求，以及数据完整性的质量保证。核心A的力量在于它的 计划内、机构内和外部顾问的良好结构，他们都致力于 通过持续的评审、建议、定期会议和建议来支持核心A领导，以确保 强劲的科学业绩和朝着商定的方案目标取得的进展。在……的指导下 核心A领导，核心A还将为研究提供支持和基础设施，促进明确和开放 所有H-CARR调查人员之间的通信，为监管监测和 合规活动，并按计划审查项目和核心活动以及实现以下目标的进度 目标。在核心A领导的指导下，核心A还将为研究提供支持和基础设施， 促进所有H-CARR调查人员之间明确和公开的沟通，参与监管监督以 优化基础机制和临床前/转化性研究的成功成果 头颈癌的药物治疗。

Administrative Core (Core A) SUMMARY The Administrative Core, led by Dr. Jeffrey Myers and Dr. Vlad Sandulache, and supported by the Center Administrator Dr. Toyin Babarinde, is an indispensable component of the Houston Center for Acquired Resistance Research (H-CARR). The overall objective of the Administrative Core (Core A) is to provide critical centralized support to the H-CARR and ensure seamless interactions and integration between the three projects and cores within the center as well as the broader ARTNet community. Core A is designed to monitor research activity and provide stable and continuous leadership that guides future scientific directions for this Research Center. Core A will leverage the wide-ranging scientific, research related experience of the Center Advisory Group in critical decision-making steps. The Administrative Core will ensure an emphasis on basic mechanistic and translational research and facilitate interdisciplinary and inter-project integration, including assistance in the establishment of collaborations with other ARTNet centers as well as the U24 ARTNet Coordinating Data and Management Center (ARTNet CDMC U24) and NCI staff. Core A will also have overall responsibility for fiscal and budgetary management of the H-CARR, including the employment of key personnel to ensure a highly qualified, well trained, managed, and diverse work force that will enable cost-effective and efficient use of resources. This Core will also monitor scientific integrity and overall compliance with all institutional, state, federal, and NCI regulations and requirements, as well as quality assurance for data integrity. The strength of Core A rest in its well-developed structure of intra-programmatic, intra-institutional, and external advisors who are all dedicated to support Core A Leaders through ongoing review, advice, and periodic meetings and recommendations to ensure robust scientific performance and progress toward the agreed upon programmatic goals. Under the direction of the Core A Leaders, Core A will also provide support and infrastructure for research, facilitate clear and open communications among all H-CARR investigators, provide a centralized resource for regulatory monitoring and compliance activities, and perform scheduled reviews of project and core activities and progress towards their goals. Under the direction of the Core A Leaders, Core A will also provide support and infrastructure for research, facilitate clear and open communications among all H-CARR investigators, engage in regulatory monitoring to optimize the successful outcome of the basic mechanistic and preclinical/translational research in resistance to drug therapy in head and neck cancer.