Data Integrity Core

点击翻译按钮获取中文摘要

SUMMARY/ABSTRACT – DATA INTEGRITY CORE The Data Integrity Core (DIC) will significantly advance our ability to address well-publicized issues of quality and reproducibility of translational, clinical, and data science driven research by leveraging the NIH FAIR (Findability, Accessibility, Interoperability, and Reusability) Guiding Principles. The goal of the DIC is to add expert level input to challenge underlying assumptions and approaches to research, going beyond the classical timely expert review and enhancements to proposed work. For example, our core team will provide a unique, independent critique for scientific strategies, ensuring diverse perspectives for methodologic approaches. The DIC will focus on specific key functions: 1) identify and curate available and novel datasets to augment the research being performed by University of Michigan ophthalmic and vision researchers; 2) work with University of Michigan researchers to collate and share effective data-use strategies across research programs, including the development of innovative, cutting-edge approaches in NIH-funded grants; 3) consult with and assist researchers to ensure appropriate analytical support, including performing granular external code review of modelling to elevate the rigor and reproducibility of investigations and the interoperability and reusability of the data generated; and 4) interface and steward researchers to University of Michigan and global resources, such as high-performance computing clusters, data management and storage facilities, and other University of Michigan cores and faculty. The impact of the DIC will be to greatly enhance the application and effectiveness of advanced data analytic strategies and accelerate the rigorous application of FAIR principles to vision research. The Core will serve a diverse group of University of Michigan NIH-funded vision scientists, spanning the spectrum from basic scientists to clinical investigators to health services and community-engaged researchers. In so doing, it will greatly enhance multidisciplinary, translational collaborations at Michigan and across the larger vision research community globally. The DIC staff will be available both virtually and in a dedicated suite within the Brehm tower of the Kellogg Eye Center, readily accessible to vision scientists. The Core will be staffed by Dr. Chris Andrews and directed by Drs. Maria Woodward and David Musch. Scheduling of DIC staff time will prioritize NEI R01-funded investigators, followed by NEI K-award recipients, other NIH R, U, and P funded scientists, other PHS U, R and P equivalent funded grants, and other vision scientists.