Research Training-Clinical Neurosciences-Stress Disorders

研究培训-临床神经科学-应激障碍

• 批准号: 7628443
• 负责人: STEVEN M M SOUTHWICK
• 金额: $ 8.12万
• 依托单位: YALE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-07-01 至 2011-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7628443
• 关键词: Clinical; Neurosciences; Research Training; Traumatic Stress Disorders

DESCRIPTION (provided by applicant): The primary purpose of this training program is to increase the number of fully trained investigators who conduct neuroscience research related to extreme stress and trauma-related disorders, such as posttraumatic stress disorder. Over the past decade exceptional pre-clinical advances have been made in understanding the physiology, biochemistry, neural circuitry, pharmacology and behavioral manifestations of stress. These advances have now made it possible to test rational hypotheses regarding the pathophysiology and treatment of stress-related disorders in humans. However, currently there are relatively few basic and clinical neuroscientists who devote their career to translating these pre-clinical findings into relevant stress-related human neurobiological research. To address this pressing need, we propose a training grant for postdoctoral fellows (advanced psychiatry residents, psychiatrists, and PhDs who have completed their doctorate in disciplines relevant to trauma-related research such as neuroscience, neurobiology, pharmacology and psychology) who seek to gain in-depth research training in the neurobiology of extreme stress and trauma-related disorders. The Yale Department of Psychiatry in collaboration with the Clinical Neurosciences Division of the National Center for PTSD and the Yale Child Study Center would provide the environment for this training grant. The fellowship would last for two years with the option to continue for a third year. Each year, two new fellows would be selected for the program. Fellows will work closely with a Program Mentor and a separate Research Mentor. These mentors will oversee all of the fellow's research and training activities. The fellowship includes a core curriculum where trainees will develop skills related to research design and methodology, statistics, ethical conduct of research, psychological and behavioral assessment and the fundamentals of trauma-relevant neuroscience. Additionally, fellows will take elective courses related to their particular research area of interest. Trainees will begin their hands-on research activity by joining an ongoing project being conducted by their Research Mentor. Then, with the help of their Research Mentor, they will design and conduct their own trauma-related research project. The Department of Psychiatry, the Clinical Neuroscience Division of the National Center for PTSD, and the Yale Child Study Center all have outstanding records of training nationally prominent researchers in the basic and clinical neurosciences. The current application seeks to contribute toward the research objectives of NIMH by training postdoctoral fellows in neuroscience research related to disorders of extreme stress.

描述（由申请人提供）：本培训计划的主要目的是增加受过充分培训的研究人员的数量，他们进行与极端压力和创伤相关疾病（如创伤后应激障碍）相关的神经科学研究。在过去的十年中，在理解压力的生理学、生物化学、神经回路、药理学和行为表现方面取得了特殊的临床前进展。这些进展现在已经有可能测试有关人类应激相关疾病的病理生理学和治疗的合理假设。然而，目前有相对较少的基础和临床神经科学家致力于将这些临床前发现转化为相关的压力相关的人类神经生物学研究。为了满足这一迫切需求，我们建议为博士后研究员（高级精神病学住院医师，精神病学家和博士，他们已经完成了与创伤相关研究相关的学科的博士学位，如神经科学，神经生物学，药理学和心理学），他们寻求在极端压力和创伤相关疾病的神经生物学方面获得深入的研究培训。耶鲁精神病学系与国家创伤后应激障碍中心临床神经科学部和耶鲁儿童研究中心合作，将为这项培训赠款提供环境。研究金为期两年，可选择继续第三年。每年将为该方案选出两名新研究员。研究员将与一个项目导师和一个单独的研究导师密切合作。这些导师将监督研究员的所有研究和培训活动。 该研究金包括一个核心课程，学员将发展与研究设计和方法，统计，研究道德行为，心理和行为评估以及创伤相关神经科学基础相关的技能。此外，研究员还将选修与他们感兴趣的特定研究领域有关的课程。学员将开始他们的动手研究活动，加入一个正在进行的项目正在进行的研究导师。然后，在他们的研究导师的帮助下，他们将设计和进行自己的创伤相关的研究项目。 精神病学系、国家创伤后应激障碍中心的临床神经科学部和耶鲁儿童研究中心都在基础和临床神经科学方面培养了全国著名的研究人员。目前的申请旨在通过培训与极端压力障碍相关的神经科学研究的博士后研究员，为NIMH的研究目标做出贡献。