Project 4/FAD Mutations in the Amyloid Precursor Protein

该项目在桑德斯实验室的背景 该项目的初步阶段由国家老龄研究所(NIA)在R21下提供资金 “探索性/发展性研究”方案(PA-03-107)。在行政削减到原来的基础上 根据项目预算，这款R21的资金为两年，在两年内每年直接支付12万美元： 5/01/06-4/30/08R21奖励是不可续订的，并且没有资格通过以下方式转换为RO1 竞争性更新。因此，这项PPG提案代表着在以下形式上确保支持的努力 为继续这项工作提供新的赠款。建议的开始日期之间有一个月的重叠 这个PPG(4/01/2008)和R21的结束将需要在行政部门解决 如果这个PPG有资金的话就是这个级别。在R21的支持下生成的数据在此处的表格中显示 “初步数据”。

Context of this Project in the Sanders Lab The preliminary phase of this project is funded by the National Institute of Aging (NIA) under the R21 "Exploratory/Developmental Research" program (PA-03-107). After administrative cuts to the original project budget, this R21 was funded for two years at <$120,000 direct per year over two years: 5/01/06-4/30/08. The R21 grant is non-renewable and is not eligible for conversion to an RO1 via competitive renewal. Therefore, this PPG proposal represents an effort to secure support in the form of a new grant to continue this work. There is one month of overlap between the proposed start date of this PPG (04/01/2008) and the end of the R21 that will need to be addressed at the administrative level if this PPG is funded. Data generated with the support of the R21 is presented here in the form of "Preliminary Data".