Training in emerging infectious diseases

描述(由申请者提供)：此申请是我们的新兴传染病(EID)T32培训计划的第一次竞争性续签。在宾夕法尼亚大学60多名主要隶属于微生物学项目的教职员工中，有14名资金雄厚的教职员工是该项目的培训者。所有培训人员都有关于新发传染病的重要研究项目，一半以上由中大西洋地区生物防御和新发传染病卓越中心(MARCE)提供部分资金，所有培训人员都参与培训活动和少数族裔招募工作。在最初的4年里，T32每年为3名博士前和2名博士后实习生提供支持，他们可以在14个不同实验室中的任何一个实验室工作，这些实验室由研究各种新出现和重新出现的病原体的研究人员指导。到目前为止，T32共资助了14名学员，几乎都是为期两年的学员，其中包括7名博士生，1名医学博士/博士生，1名VMD/博士生和5名博士后研究员。这14名学员曾在9个不同培训师的实验室工作过。在14名现任和过去的受训人员中，8名是女性，6名是男性，2名是少数民族。在完成培训并离开宾夕法尼亚大学的3名博士后研究员中，1人是助理教授，1人是NIH的研究员，他在那里研究埃博拉病毒，1人在工业领域开发病毒疫苗。在离开宾夕法尼亚大学的三名学生中，有两名是博士后研究员，他们在那里继续研究传染病，一名是工业界的科学家。另外两名即将毕业的学生将分别在USAMRIID和疾控中心特殊病原体分部从事博士后研究。开斋节T32计划帮助我们的研究人员和受训人员团结起来，他们研究许多不同的病原体，以其他方式不会发生的方式。在T32获得资金后，培训者开发了一门现在很受欢迎的研究生级别的新兴传染病课程，开始了每月一次的人畜共患病研讨会系列，由我们的教职员工和学员参加，并开始了一项倡议，在该计划中，我们所有的学员都接受了广泛的BSL3培训。我们启动了公共卫生证书课程，以回应我们许多学员对新出现的传染病和全球健康问题感兴趣的事实，并于今年夏天推出了一个为期3周的夏季生物统计学课程，让我们的学员学习，认识到大部分开斋节文献包括流行病学研究，以及相信更强的统计学和量化方法背景将有助于我们的学员为科学生涯做准备。我们还派遣学员参加每年举行两次的区域MARCE会议，这反过来又为我们的学员带来了新的合作以及培训机会。鉴于需要继续培训年轻科学家从事新出现的传染病的工作，我们建议更新这一成功的计划。由于T32助学金的资金环境困难，我们建议将该项目维持在目前每年3名学生和2名博士后的规模。

DESCRIPTION (provided by applicant): This application represents the first competitive renewal for our Training in Emerging Infectious Diseases (EID) T32 program. Of the more than 60 faculty at the University of Pennsylvania whose primary affiliation is with the microbiology program, a select group of 14 well-funded faculty are trainers in this program. All of the trainers have significant research programs in emerging infectious diseases, more than half are funded in part by the Middle Atlantic Regional Center of Excellence (MARCE) in Biodefense and Emerging Infectious Diseases, and all participate in training activities and minority recruitment efforts. During its first 4 years, this T32 provided support for 3 predoctoral and 2 postdoctoral trainees per year who could work in any one of 14 different laboratories directed by investigators who study a variety of emerging and re-emerging pathogens. To date, a total of 14 trainees have been supported by this T32, virtually all for 2 years, including 7 Ph.D. students, 1 M.D./Ph.D. student, 1 VMD/Ph.D. student and 5 Ph.D. postdoctoral fellows. These 14 trainees have worked in the labs of 9 different trainers. Of the 14 current and past trainees, 8 are women, 6 are men, and 2 are minorities. Of the 3 postdoctoral fellows who have completed their training and left Penn, one is an Assistant Professor, one is a staff scientist at the NIH where he studies Ebola virus, and one is in industry developing viral vaccines. Of the 3 students who have left Penn, two are postdoctoral fellows where they continue to study infectious diseases, and one is a scientist in industry. Two additional students who will graduate soon will be undertaking postdoctoral fellowships at USAMRIID and the Special Pathogens Branch of the CDC, respectively. The EID T32 program has served to unite our investigators and trainees, who study many different pathogens, in ways that would not otherwise have occurred. After the T32 was funded, the trainers developed what is now a popular graduate level course on emerging infectious diseases, started a monthly Zoonotic Diseases Seminar series that is attended by our faculty and trainees, and began an initiative in which all of our trainees receive extensive BSL3 training. We have started a Certificate Program in Public Health in response to the fact that so many of our trainees are interested in emerging infectious diseases and global health issues, and this summer launched a 3-week long summer biostatistics course to betaken by our trainees, recognizing that much of the EID literature consists of epidemiological studies coupled with the belief that a stronger background in statistics and quantitative methods will help prepare our trainees for careers in science. We also send our trainees to the regional MARCE meetings, held twice each year, and this in turn has led to new collaborations for our trainees as well as training opportunities. In light of the need to continue to train young scientists to work in emerging infectious diseases, we propose to renew this successful program. Due to the difficult funding climate for T32 grants, we propose to maintain this program at its present size of 3 students and 2 postdocs per year.