课题基金 / 基金详情

High-Resolution Bidirectional Optical-Acoustic Mesoscopic Neural Interface for Image-Guided Neuromodulation in Behaving Animals - RF1 Admin Supplement

High-Resolution Bidirectional Optical-Acoustic Mesoscopic Neural Interface for Image-Guided Neuromodulation in Behaving Animals - RF1 Admin Supplement
用于行为动物图像引导神经调节的高分辨率双向光声介观神经接口 - RF1 管理补充
批准号:
10712937
负责人:
Robert E. Campbell
金额:
$42.38万
依托单位国家:
美国
项目类别:
财政年份:
2023
资助国家:
美国
项目状态:
未结题
起止时间:
2023-04-01 至 2025-05-31

项目摘要

项目成果

Robert E. Campbell的其他基金

相关文献

中文摘要
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摘要
英文摘要
ABSTRACT Neuroscience has an essential requirement for large-scale imaging and perturbation tools. Such tools would be transformative in the mapping of brain function and the diagnosis and treatment of neurological disorders. The proposed project is aimed at uncovering regulation of glymphatic and vascular flow in the progression of Alzheimer’s disease (AD) at whole-brain, cellular-resolution scales using novel whole-brain imaging modalities. Our project’s goal is to use state-of-the-art in vivo imaging techniques to study cerebrospinal fluid (CSF) flow in the brain, and how this flow interacts with AD-related protein accumulation in transgenic models. We will study how flow in this system is perturbed in AD, with a focus on clearance of waste products
期刊论文(4)
专著(0)
科研奖励(0)
会议论文
DOI: 10.1038/s41467-023-39069-1
发表时间: 2023-06-16
期刊: NATURE COMMUNICATIONS
影响因子: 16.6
作者: [Dean-Ben, Xose Luis, Robin, Justine, Nozdriukhin, Daniil, Ni, Ruiqing, Zhao, Jim, Gluck, Chaim, Droux, Jeanne, Sendon-Lago, Juan, Chen, Zhenyue, Zhou, Quanyu, Weber, Bruno, Wegener, Susanne, Vidal, Anxo, Arand, Michael, El Amki, Mohamad, Razansky, Daniel]
通讯作者: Razansky, Daniel
High-resolution bidirectional optical-acoustic mesoscopic neural interface for image-guided neuromodulation in behaving animals
Optimization of CaMPARI for large-scale, cellular-resolution activity recording in freely-moving mice
  • 批准号:
    10293936
  • 项目类别:
  • 资助金额:
    $61.91万
  • 财政年份:
    2021
  • 负责人:
    Robert E. Campbell
  • 依托单位:
Optimization of CaMPARI for large-scale, cellular-resolution activity recording in freely-moving mice
  • 批准号:
    10472700
  • 项目类别:
  • 资助金额:
    $64.81万
  • 财政年份:
    2021
  • 负责人:
    Robert E. Campbell
  • 依托单位:
Northern Lights collaboration for better 2-photon probes