Cancer Epidemiology, Prevention and Control Program

癌症流行病学、预防和控制计划

• 批准号: 10712882
• 负责人: H Dean Hosgood
• 金额: $ 5.61万
• 依托单位: ALBERT EINSTEIN COLLEGE OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-06-01 至 2028-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10712882
• 关键词: Address; Advanced Malignant Neoplasm; Affect; Articulation; Back; Behavioral; Biological; Biological Models; Black race; Cancer Burden; Cancer Center; Cancer Center Support Grant; Cancer Control; Cancer Etiology; Cancer Patient; Catchment Area; Cervical Cancer Screening; Clinical; Clinical Data; Collaborations; Communities; Community Outreach; County; Detection; Development; Disparity; Early Diagnosis; Effectiveness; Ensure; Epigenetic Process; Etiology; Evolution; Genetic; Goals; Guidelines; HIV; Health; Health Personnel; Health Services Accessibility; Health system; Home; Human; Human Papillomavirus; Incidence; Individual; Inequity; Institution; International; Intervention; Laboratories; Language; Latinx; Leadership; Malignant Neoplasms; Malignant neoplasm of cervix uteri; Malignant neoplasm of lung; Malignant neoplasm of prostate; Mentors; Minority; Mission; Modeling; Molecular; NCI Center for Cancer Research; Nature; New York; Obesity associated cancer; Organ; Outcome; Participant; Patients; Peer Review; Personal Satisfaction; Persons; Play; Policies; Population; Population Heterogeneity; Population Research; Population Study; Poverty; Predisposition; Prevention; Principal Investigator; Productivity; Public Health; Public Health Practice; Quality of life; Research; Research Design; Research Personnel; Risk Factors; Role; Shapes; Statistical Methods; Strategic Planning; Supportive care; Testing; Tobacco smoking behavior; Training; Translating; Translations; Variant; Vulnerable Populations; Western Africa; Work; anticancer research; cancer care; cancer education; cancer epidemiology; cancer health disparity; cancer prevention; care delivery; care outcomes; clinical practice; community engagement; community involvement; community setting; design; effectiveness testing; electronic medical record system; equity, diversity, and inclusion; fire fighter; health inequalities; high risk; high risk population; improved; infection related cancer; innovation; malignant breast neoplasm; member; mortality; multiple chronic conditions; non-smoker; novel; novel therapeutic intervention; outreach; patient retention; prevent; programs; psychosocial; screening; smoking intervention; social; social determinants; social health determinants; trend; tumor; virtual

Program Director/Principal Investigator (Last, First, Middle): Chu, Edward CANCER EPIDEMIOLOGY, PREVENTION AND CONTROL PROGRAM – PROJECT SUMMARY/ABSTRACT The Cancer Epidemiology, Prevention and Control (CEPC) Program plays a central role in the scientific, clinical, and public health mission of MECC. The Program’s overarching goal is to better understand and address drivers of cancer burden and cancer disparities in our Bronx catchment area and other vulnerable populations. Program investigators focus on studies in human populations to determine the behavioral, environmental, and molecular risk factors that underlie cancer etiology and outcomes, leading to studies that devise, implement and test the effectiveness of novel interventions to promote cancer prevention, screening, treatment and supportive care. Program members collaborate extensively with one another and with the other three MECC research programs. Given the inter- and trans-disciplinary nature of this program, CEPC is the focal point for translating laboratory- based research into population level studies and for bridging findings from clinical and community settings back to the lab. CEPC has three specific aims: (1) to characterize the risk factors that drive cancer health disparities in our catchment area, most notably breast, lung, prostate, and cervical cancer; (2) to improve cancer prevention and screening among vulnerable and high-risk groups in our catchment area and beyond; and (3) to develop and implement innovative strategies to enhance cancer care outcomes. CEPC research has contributed to improved health of the largely poor and minoritized Bronx population, as well as populations worldwide. Completed and ongoing research in CEPC has substantively influenced clinical guidelines and public health practice, with new studies poised to continue this trend. CEPC research: (i) has identified novel susceptibility markers for breast cancer, prostate cancer, CRC, and lung cancer in non-smokers -- the major causes of cancer mortality in the Bronx – demonstrating efforts to understand the mechanisms of cancer in an environmental and behavioral context; (ii) contributed to major policy decisions regarding cancer care of firefighters who worked at the 9/11 WTC; (iii) developed innovative in-reach and outreach strategies that overcome social determinants to increase early detection and timely access to care; (iv) developed effective tobacco smoking interventions that have been integrated in to standard clinical practice, as well as in clinical guidelines for persons living with HIV; (v) implemented comprehensive cervical cancer screening and treatment in Western Africa; and (vi) introduced a novel appraisal paradigm that emphasizes patients’ own personal criteria for quality of life. OMB No. 0925-0001/0002 (Rev. 03/2020 Approved Through 02/28/2023) Page

项目主任/首席调查员(最后、第一、中间)：朱 癌症流行病学、预防和控制程序--项目摘要/摘要 癌症流行病学、预防和控制(CEPC)计划在科学、临床和医疗领域发挥着核心作用。 和MECC的公共卫生使命。该计划的首要目标是更好地理解和解决司机问题 我们的布朗克斯集水区和其他弱势群体的癌症负担和癌症差异。计划 研究人员专注于在人类群体中进行研究，以确定行为、环境和分子 癌症病因和结果背后的风险因素，导致设计、实施和测试 促进癌症预防、筛查、治疗和支持性护理的新干预措施的有效性。 计划成员彼此之间以及与其他三个MECC研究计划广泛合作。 鉴于这一项目的跨学科性质，CEPC是翻译实验室- 以人口水平研究为基础的研究，并将临床和社区环境中的研究结果联系起来 去实验室。CEPC有三个具体目标：(1)描述导致癌症健康差异的风险因素 在我们的集水区，最明显的是乳腺癌、肺癌、前列腺癌和宫颈癌；(2)改善癌症预防 在我们的集水区和其他地区的弱势群体和高危群体中进行筛查；以及(3)发展 并实施创新战略，以提高癌症护理成果。CEPC的研究有助于 改善布朗克斯大部分贫困人口和少数族裔人口以及全世界人口的健康状况。 CEPC已完成和正在进行的研究对临床指南和公众健康产生了实质性影响 实践，随着新的研究准备延续这一趋势。CEPC研究：(I)已确定新的易感性 乳腺癌、前列腺癌、结直肠癌和非吸烟者肺癌的标志物--癌症的主要原因 布朗克斯的死亡率-展示了在环境和环境中了解癌症机制的努力 行为背景；(Ii)为有关在以下地点工作的消防员的癌症护理的重大决策做出贡献 9/11世贸中心；(3)制定了创新的深入和外联战略，克服了社会决定因素，以 增加早期发现和及时获得护理的机会；(4)制定有效的吸烟干预措施， 已纳入标准临床实践以及艾滋病毒携带者临床指南； (V)在西非实施了全面的宫颈癌筛查和治疗；和(Vi) 一种新的评估范式，强调患者自己的个人生活质量标准。 OMB编号0925-0001/0002(截至2023年2月28日批准的第03/2020版)页面