Methods and Logic in Molecular Biology Training Program

分子生物学方法与逻辑培训计划

基本信息

  • 批准号:
    10721701
  • 负责人:
  • 金额:
    $ 88.93万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2023
  • 资助国家:
    美国
  • 起止时间:
    2023-07-01 至 2028-06-30
  • 项目状态:
    未结题

项目摘要

The Methods and Logic in Molecular Biology training program (MLMB) at Princeton University educates carefully selected individuals for the research, teaching, and advocacy needs of the nation. The MLMB brings together the multi-disciplinary life science community at Princeton with 54 training faculty. Our program is highly collaborative and trains students to acquire the skills to become leaders in any field they choose. The MLMB training faculty represent 7 academic departments and 3 research institutes, including 33 from Molecular Biology, 4 from Chemistry, 5 from Chemical & Biological Engineering, 2 from Ecology & Evolutionary Biology, 3 from Computer Science, 2 from Physics, 2 from Mechanical & Aerospace Engineering, 1 from the Lewis Sigler Genomics Institute, and 2 from the Neuroscience Institute. The faculty provides expertise in diverse biological model systems, offering training in genetics, genomics, proteomics, metabolomics, biochemistry, biophysics, cancer, cell biology, development, microbiology, immunology, and neuroscience. All faculty are themselves rigorously mentored, undergoing annual mandatory mentoring training, and assessed by the MLMB Committee. The MLMB is administratively supported by the Department of Molecular Biology (MOL) and selects its students from the pool of MOL graduate students. The MLMB is the only training grant that supports MOL students. The MOL graduate program receives over 400 applications per year, attracting some of the best students in the country. Research is performed in well-equipped laboratories with support from state-of-the-art core facilities. The training program consists of inter-disciplinary, skill-building oriented course work, laboratory rotations, a general exam, thesis research, thesis committee meetings, Individual Developmental Plans, and an array of MLMB specialized courses and activities that provide students with science communication, leadership, and managements skills, in conjunction with diverse career development opportunities. Trainees gain teaching experience and receive intensive training in scientific rigor/reproducibility and responsible conduct of research. Our Mentorship Program further helps all students with issues such as work/life balance and career development. We have a successful Diversity and Inclusion Program to help recruit and retain students from groups that are under-represented in the life sciences. Our gender and racial demographics have matched those of the nation for over a decade. Routine internal and external assessment of the MLMB Training Program evaluates both faculty and students and enables us to identify needs for new courses, policies, and activities that keep the program fresh. Our success is best judged by the productivity and success of our graduates. Students who graduated in the past 10 years had an average of 4.1 publications per trainee and 95% are still engaged in science-related careers. Our MLMB program thus nucleates the vibrant multi-disciplinary research community at Princeton and delivers scientists broadly trained with the interdisciplinary skills they need to solve tomorrow’s challenges. Support for 12 trainees for their 2nd and 3rd years (24 slots) is requested.
普林斯顿大学的分子生物学培训项目(MLMB)的方法和逻辑教育很仔细 为国家的研究,教学和宣传需要选择个人。MLMB汇集了 普林斯顿大学的多学科生命科学社区,有54名培训教师。我们的计划是高度 协作和培训学生获得技能,成为他们选择的任何领域的领导者。MLMB 培训教师代表7个学术部门和3个研究机构,其中33人来自分子生物学, 4从化学,5从化学与生物工程,2从生态与进化生物学,3从 计算机科学,2名来自物理学,2名来自机械与航空航天工程,1名来自刘易斯西格勒 基因组学研究所和2个来自神经科学研究所。该学院提供各种生物学方面的专业知识, 模型系统,提供遗传学,基因组学,蛋白质组学,代谢组学,生物化学,生物物理学, 癌症、细胞生物学、发育、微生物学、免疫学和神经科学。所有教师都是自己 受到严格的指导,接受年度强制性指导培训,并由MLMB委员会评估。 MLMB由分子生物学系(MOL)提供行政支持,并选择学生 从MOL的研究生中脱颖而出。MLMB是支持MOL学生的唯一培训补助金。的 MOL研究生课程每年收到400多份申请,吸引了世界上一些最好的学生。 国家研究在设备齐全的实验室进行,并得到最先进的核心设施的支持。 培训计划包括跨学科,技能建设为导向的课程工作,实验室轮换, 一般考试,论文研究,论文委员会会议,个人发展计划,以及一系列 MLMB专业课程和活动,为学生提供科学交流,领导力, 管理技能,以及多样化的职业发展机会。学员获得教学 在科学严谨性/可重复性和负责任的研究行为方面经历并接受强化培训。 我们的导师计划进一步帮助所有学生解决工作/生活平衡和职业等问题 发展我们有一个成功的多样性和包容性计划,以帮助招募和留住学生从 在生命科学领域代表性不足的群体。我们的性别和种族人口统计数据与那些 十多年来一直是全国最大的MLMB培训计划的常规内部和外部评估 评估教师和学生,使我们能够确定新课程,政策和活动的需求 让节目保持新鲜感我们的成功是最好的判断我们的毕业生的生产力和成功。 在过去10年中毕业的学生平均每人发表4.1篇论文,95%的学生仍然在 从事与科学相关的职业。因此,我们的MLMB计划是充满活力的多学科研究的核心 社区在普林斯顿大学,并提供科学家广泛培训,他们需要解决跨学科的技能 明天的挑战要求为12名第二年和第三年的受训人员(24个名额)提供支助。

项目成果

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Ileana M. Cristea其他文献

The protein composition of human adenovirus replication compartments
人腺病毒复制区室的蛋白质组成
  • DOI:
    10.1128/mbio.02144-24
  • 发表时间:
    2024-11-29
  • 期刊:
  • 影响因子:
    4.700
  • 作者:
    Paloma Hidalgo;Amada Torres;Pierre M. Jean Beltran;Gamaliel López-Leal;Luca D. Bertzbach;Thomas Dobner;S. J. Flint;Ileana M. Cristea;Ramón A. González
  • 通讯作者:
    Ramón A. González
Fpa (YlaN) is an iron(II) binding protein that functions to relieve Fur-mediated repression of gene expression in emStaphylococcus aureus/em
Fpa(YlaN)是一种铁(II)结合蛋白,其作用是缓解金黄色葡萄球菌中 Fur 介导的基因表达抑制。
  • DOI:
    10.1128/mbio.02310-24
  • 发表时间:
    2024-10-09
  • 期刊:
  • 影响因子:
    4.700
  • 作者:
    Jeffrey M. Boyd;Kylie Ryan Kaler;Karla Esquilín-Lebrón;Ashley Pall;Courtney J. Campbell;Mary E. Foley;Gustavo Rios-Delgado;Emilee M. Mustor;Timothy G. Stephens;Hannah Bovermann;Todd M. Greco;Ileana M. Cristea;Valerie J. Carabetta;William N. Beavers;Debashish Bhattacharya;Eric P. Skaar;Lindsey N. Shaw;Timothy L. Stemmler
  • 通讯作者:
    Timothy L. Stemmler
emIn vitro/em and emex vivo/em proteomics of emMycobacterium marinum/em biofilms and the development of biofilm-binding synthetic nanobodies
海分枝杆菌生物膜的体外和体内蛋白质组学以及生物膜结合合成纳米抗体的开发
  • DOI:
    10.1128/msystems.01073-22
  • 发表时间:
    2023-05-03
  • 期刊:
  • 影响因子:
    4.600
  • 作者:
    Milka Marjut Hammarén;Hanna Luukinen;Alina Sillanpää;Kim Remans;Karine Lapouge;Tânia Custódio;Christian Löw;Henna Myllymäki;Toni Montonen;Markus Seeger;Joseph Robertson;Tuula A. Nyman;Kirsi Savijoki;Mataleena Parikka;Ileana M. Cristea;Paul Cos
  • 通讯作者:
    Paul Cos
A Primer on Proteomic Characterization of Intercellular Communication in a Virus Microenvironment
病毒微环境中细胞间通讯的蛋白质组学表征入门
  • DOI:
    10.1016/j.mcpro.2025.100913
  • 发表时间:
    2025-03-01
  • 期刊:
  • 影响因子:
    5.500
  • 作者:
    James C. Kostas;Colter S. Brainard;Ileana M. Cristea
  • 通讯作者:
    Ileana M. Cristea
Liquid–liquid phase separation in innate immunity
天然免疫中的液-液相分离
  • DOI:
    10.1016/j.it.2024.04.009
  • 发表时间:
    2024-06-01
  • 期刊:
  • 影响因子:
    13.900
  • 作者:
    Dawei Liu;Jinhang Yang;Ileana M. Cristea
  • 通讯作者:
    Ileana M. Cristea

Ileana M. Cristea的其他文献

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{{ truncateString('Ileana M. Cristea', 18)}}的其他基金

Dynamic virus-driven remodeling of ER-mitochondria contacts
内质网-线粒体接触的动态病毒驱动重塑
  • 批准号:
    10707412
  • 财政年份:
    2022
  • 资助金额:
    $ 88.93万
  • 项目类别:
Dynamic virus-driven remodeling of ER-mitochondria contacts
内质网-线粒体接触的动态病毒驱动重塑
  • 批准号:
    10608035
  • 财政年份:
    2022
  • 资助金额:
    $ 88.93万
  • 项目类别:
Mechanisms mediating immune response upon sensing of nuclear viral DNA
感测核病毒 DNA 介导免疫反应的机制
  • 批准号:
    10266082
  • 财政年份:
    2015
  • 资助金额:
    $ 88.93万
  • 项目类别:
Mechanisms mediating immune response upon sensing of nuclear viral DNA
感测核病毒 DNA 介导免疫反应的机制
  • 批准号:
    9027921
  • 财政年份:
    2015
  • 资助金额:
    $ 88.93万
  • 项目类别:
Mechanisms mediating immune response upon sensing of nuclear viral DNA
感测核病毒 DNA 介导免疫反应的机制
  • 批准号:
    9973554
  • 财政年份:
    2015
  • 资助金额:
    $ 88.93万
  • 项目类别:
Mechanisms mediating immune response upon sensing of nuclear viral DNA
感测核病毒 DNA 介导免疫反应的机制
  • 批准号:
    10672215
  • 财政年份:
    2015
  • 资助金额:
    $ 88.93万
  • 项目类别:
Mechanisms mediating immune response upon sensing of nuclear viral DNA
感测核病毒 DNA 介导免疫反应的机制
  • 批准号:
    10456254
  • 财政年份:
    2015
  • 资助金额:
    $ 88.93万
  • 项目类别:
Host Factors Required for Dengue and Yellow Fever Virus Amplification
登革热和黄热病病毒扩增所需的宿主因素
  • 批准号:
    8522155
  • 财政年份:
    2012
  • 资助金额:
    $ 88.93万
  • 项目类别:
Host Factors Required for Dengue and Yellow Fever Virus Amplification
登革热和黄热病病毒扩增所需的宿主因素
  • 批准号:
    8391158
  • 财政年份:
    2012
  • 资助金额:
    $ 88.93万
  • 项目类别:
Proteomic Tools to Uncover the Role of Chromatin Remodeling in HIV-1 Infection
揭示染色质重塑在 HIV-1 感染中作用的蛋白质组学工具
  • 批准号:
    8117154
  • 财政年份:
    2008
  • 资助金额:
    $ 88.93万
  • 项目类别:

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Computational Methods for Analyzing Toponome Data
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Elucidation of the mechanism of urinary stone formation and the establishment of novel preventive methods through the integration of molecular biology, mineralogy, and meteoritics.
通过分子生物学、矿物学和陨石学的整合,阐明泌尿系结石形成的机制并建立新的预防方法。
  • 批准号:
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  • 财政年份:
    2020
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  • 项目类别:
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The Molecular Biology of FMDV Replication: Towards New Methods of FMDV Disease Control.
口蹄疫病毒复制的分子生物学:口蹄疫疾病控制的新方法。
  • 批准号:
    BB/K003801/1
  • 财政年份:
    2013
  • 资助金额:
    $ 88.93万
  • 项目类别:
    Research Grant
2012 Diffraction Methods in Molecular Biology Gordon Research Conference
2012 分子生物学衍射方法戈登研究会议
  • 批准号:
    8314293
  • 财政年份:
    2012
  • 资助金额:
    $ 88.93万
  • 项目类别:
III: Small: Combinatorial Optimization Methods for Problems in Molecular Biology and Genetics
III:小:分子生物学和遗传学问题的组合优化方法
  • 批准号:
    1217615
  • 财政年份:
    2012
  • 资助金额:
    $ 88.93万
  • 项目类别:
    Continuing Grant
Collaborative Research: Combining Methods from Geochemistry and Molecular Biology to Predict the Functions of Microbial Communities
合作研究:结合地球化学和分子生物学的方法来预测微生物群落的功能
  • 批准号:
    1123649
  • 财政年份:
    2011
  • 资助金额:
    $ 88.93万
  • 项目类别:
    Standard Grant
Collaborative Research: Combining Methods from Geochemistry and Molecular Biology to Predict the Functions of Microbial Communities
合作研究:结合地球化学和分子生物学的方法来预测微生物群落的功能
  • 批准号:
    1123689
  • 财政年份:
    2011
  • 资助金额:
    $ 88.93万
  • 项目类别:
    Standard Grant
Diffraction Methods in Molecular Biology Gordon Research Conference
分子生物学中的衍射方法戈登研究会议
  • 批准号:
    7902980
  • 财政年份:
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  • 资助金额:
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  • 项目类别:
Molecular biology methods to study the influence of feed supplements on structure and selected functions of intestinal beacterial communities in piglets (A01)
分子生物学方法研究饲料添加剂对仔猪肠道细菌群落结构和选择功能的影响(A01)
  • 批准号:
    165009948
  • 财政年份:
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  • 资助金额:
    $ 88.93万
  • 项目类别:
    Collaborative Research Centres
CAREER: Geometric and Topological Methods in Shape Analysis, with Applications in Molecular Biology
职业:形状分析中的几何和拓扑方法及其在分子生物学中的应用
  • 批准号:
    0747082
  • 财政年份:
    2008
  • 资助金额:
    $ 88.93万
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Bayesian Methods and Experimental Design for Molecular Biology Experiments
分子生物学实验的贝叶斯方法和实验设计
  • 批准号:
    7325828
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