Pilot Projects Program

尽管俄克拉荷马州的一些健康领域最近有所改善，但烟草率仍然居高不下。 物质使用、肥胖、癌症和心血管疾病死亡、关节炎残疾和糟糕的整体健康选择。 OSCTR试点项目计划的使命是加速发现俄克拉荷马州的健康优先事项 通过促进创新和协作的临床和转化研究(CTR)项目，在全国范围内 以及联邦政府资助的独立研究项目。我们的计划已经资助了50个试点项目，其中50% 女性，其中20%来自代表性不足的少数民族人口。这些试点获奖者已经 非常成功地为这些新的调查人员争取到了超过9000万美元的PI级别的外部资金， 其中包括每年超过1000万美元的联邦资金。该方案提供试点项目资金(目标1)， 协调对试点调查人员的基础设施支持和指导(目标2)，并确定有希望的 没有经费的初级调查员需要额外指导(目标3)。这一战略建立在这样一个假设之上： 为初级调查人员提供CTR资金、基础设施和指导将凝聚新一代 训练有素、资金充足的CTR科学家，他们有能力将科学发现转化为改进的临床 关爱和病人的福祉。试点计划优先考虑解决以下突出健康问题的研究 俄克拉荷马州和其他理想州。建立在早期成功的基础上，并响应过去确定的需求 试点、EAC和评估核心反馈，该计划正在增加对试点PI的行政支持，以 在赠款管理技能方面提供更多指导。它将继续提供两种类型的奖项：CTR飞行员奖 每年为至少五个新的研究项目提供12个月的资金；试点可持续发展桥 奖励每年可为最多2名试点获奖者提供额外6个月的资金，以满足以下需求 在分析、出版和为他们的项目寻求外部资金的同时提供临时支持。我们鼓励 试点项目，支持我们合作伙伴的独特需求，合作伙伴包括非学术机构 机构，如部落机构、社区发展机构、县卫生改善 组织和初级保健提供者。除了这些由OSCTR资助的奖项外，该计划还利用 其他地方资助计划，尽可能在每个类别中提供更大或更多的奖励。超越 通过提供财政支持，该方案明显表明，它提供了一种 培养了这些初级调查员的成功。一年一度的飞行员启动会议将向获奖者介绍 OSCTR核心、导演和其他获奖者。在整个颁奖过程中，调查人员将收到结构化的 指导(专业发展核心)和科学写作培训，以促进职业发展和 走向独立的成长，包括通过提案批评机会进行同行指导。该计划 继续协助目前和过去的获奖者以及有前途但没有资金的申请者确定 提供更多的资金来源，并制定一项战略，确保获得独立的国家资金。

Despite recent improvements in some area of health, Oklahoma continues to have high rates of tobacco and substance use, obesity, cancer and cardiovascular deaths, arthritis disability and poor overall health choices. The mission of the OSCTR Pilot Projects Program is to accelerate discoveries into Oklahoma’s health priorities by fostering innovative and collaborative clinical and translational research (CTR) projects, leading to nationally and federally funded independent research programs. Our program has funded 50 pilot projects with >50% female and 20% of these PIs from under-represented minority populations. These pilot recipients have been immensely successful garnering more than $90M of PI-level extramural funding to these new investigators, including more than $10M annual federal funding. This program provides pilot project funding (Aim 1), coordinates infrastructure support and mentoring for pilot investigators (Aim 2), and identifies promising but unfunded junior investigators for additional mentoring (Aim 3). This strategy is built on the hypothesis that providing junior investigators with CTR funding, infrastructure, and mentorship will coalesce a new generation of well-trained, well-funded CTR scientists equipped to translate scientific discoveries into improved clinical care and patient well-being. The Pilot program prioritizes research that addresses prominent health issues in Oklahoma and other IDeA states. Building on early successes and being responsive to needs identified by past pilots, EAC and Evaluation Core feedback, the program is increasing its administrative support to Pilot PIs to provide more mentoring in grant management skills. It is continuing to offer two award types: CTR Pilot Awards provide 12 months of funding for at least five novel research projects per year; Pilot Sustainability Bridge Awards can provide 6 additional months of funding for up to 2 pilot recipients per year to address the need for interim support while analyzing, publishing, and seeking extramural funding for their projects. We encourage Pilot projects that support the unique needs of our partners with partnerships that include non-academic institutions, such as tribal institutions, community development agencies, county health improvement organizations, and primary care providers. In addition to these OSCTR-funded awards, the program leverages other local funding programs when possible to provide larger or additional awards in each category. Beyond providing financial support, the program had demonstrably demonstrated that it provides an environment that nurtures the success of these junior investigators. Annual Pilot initiation meetings will introduce awardees to the OSCTR Cores, Directors, and other awardees. Throughout the award, investigators will receive structured mentoring (Professional Development Core) and training in scientific writing to foster career development and growth toward independence, including peer mentoring through proposal critique opportunities. The program continues to assist current and past awardees, as well as promising but unfunded applicants, to identify additional funding sources and develop a strategy for securing independent, national funding.